163089-71-2
163089-71-2
Chemical Structure
Huperzine C
- CAS No.: 163089-71-2
- Formula:C15H18N2O
- Molecular Weight:242.32
IUPAC Name: (5R,9R,11R)-5-amino-7-methyl-11-vinyl-5,6,9,10-tetrahydro-5,9-methanocycloocta[b]pyridin-2(1H)-one
InChIKey: IZGRHSRWTILCID-FIXISWKDSA-N
SMILES: O=C1C=CC([C@@]([C@@H]2C=C)(N)CC(C)=C[C@@]2([H])C3)=C3N1
Biological Activity: Huperzine C is an alkaloid isolated from Huperzia serrate. Huperzine C is an acetylcholinesterase (AChE) inhibotor, with an IC50 of 0.6 μM. Huperzine C can be used for the research of Alzheimer’s disease[1][2].
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Huperzine C | Huperzine C is an alkaloid isolated from Huperzia serrate. Huperzine C is an acetylcholinesterase (AChE) inhibotor, with an IC50 of 0.6 μM. Huperzine C can be used for the research of Alzheimer’s disease. | |||||||||||||||||||||
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References
- [1]. Fangfang Jiang, et al. Lycopodium alkaloids from Huperzia serrate. Fitoterapia.. 2019 Sep;137:104277. [Content Brief]
- [2]. Dong-Bo Zhang, et al. Lycodine-Type Alkaloids from Lycopodiastrum casuarinoides and Their Acetylcholinesterase Inhibitory Activity. Molecules. 2014 Jul; 19(7): 9999–10010. [Content Brief]
Keywords
