1. Natural Products
  2. Disease Research Fields Plants Alkaloids
  3. Rutaceae Inflammation/Immunology Quinoline Alkaloids
  4.  Skimmia reevesiana Fort.
  5. Skimmianine

Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity.

For research use only. We do not sell to patients.

Skimmianine Chemical Structure

Skimmianine Chemical Structure

CAS No. : 83-95-4

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 200 In-stock
Solution
10 mM * 1 mL in DMSO USD 200 In-stock
Solid
1 mg USD 70 In-stock
5 mg USD 195 In-stock
10 mg USD 310 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Skimmianine

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1].

Molecular Weight

259.26

Formula

C14H13NO4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC1=C2N=C(OC=C3)C3=C(OC)C2=CC=C1OC

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (128.56 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8571 mL 19.2857 mL 38.5713 mL
5 mM 0.7714 mL 3.8571 mL 7.7143 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8571 mL 19.2857 mL 38.5713 mL 96.4283 mL
5 mM 0.7714 mL 3.8571 mL 7.7143 mL 19.2857 mL
10 mM 0.3857 mL 1.9286 mL 3.8571 mL 9.6428 mL
15 mM 0.2571 mL 1.2857 mL 2.5714 mL 6.4286 mL
20 mM 0.1929 mL 0.9643 mL 1.9286 mL 4.8214 mL
25 mM 0.1543 mL 0.7714 mL 1.5429 mL 3.8571 mL
30 mM 0.1286 mL 0.6429 mL 1.2857 mL 3.2143 mL
40 mM 0.0964 mL 0.4821 mL 0.9643 mL 2.4107 mL
50 mM 0.0771 mL 0.3857 mL 0.7714 mL 1.9286 mL
60 mM 0.0643 mL 0.3214 mL 0.6429 mL 1.6071 mL
80 mM 0.0482 mL 0.2411 mL 0.4821 mL 1.2054 mL
100 mM 0.0386 mL 0.1929 mL 0.3857 mL 0.9643 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Skimmianine
Cat. No.:
HY-N2081
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