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Results for "

protein-tyrosine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	BRK (1) FLT3 (1) 5-HT Receptor (2) Aldose Reductase (1) Antibiotic (7) Apoptosis (12) Autophagy (2) Bacterial (5) Bcr-Abl (1) Beta-secretase (1) Biochemical Assay Reagents (3) c-Met/HGFR (3) CaMK (1) COX (1) Cytochrome P450 (1) EGFR (8) Endogenous Metabolite (1) FGFR (1) Fluorescent Dye (1) Fungal (5) Glucosidase (2) Histone Methyltransferase (1) HIV (1) Insulin Receptor (1) Isotope-Labeled Compounds (1) JAK (3) Monoamine Oxidase (2) p38 MAPK (1) Parasite (10) PDGFR (1) Phosphatase (74) Phosphodiesterase (PDE) (1) Phospholipase (1) PKA (1) PKC (1) PTEN (2) Reverse Transcriptase (3) SARS-CoV (2) SHP2 (9) Sirtuin (2) Src (6) STAT (1) Tie (2) Topoisomerase (3) Trk Receptor (1) VEGFR (1) Xanthine Oxidase (1)
By Research Areas:	Cancer (45) Cardiovascular Disease (6) Endocrinology (4) Infection (12) Inflammation/Immunology (10) Metabolic Disease (34) Neurological Disease (8)

By Targets:

BRK (1)

FLT3 (1)

5-HT Receptor (2)

Aldose Reductase (1)

Antibiotic (7)

Apoptosis (12)

Autophagy (2)

Bacterial (5)

Bcr-Abl (1)

Beta-secretase (1)

Biochemical Assay Reagents (3)

c-Met/HGFR (3)

CaMK (1)

COX (1)

Cytochrome P450 (1)

EGFR (8)

Endogenous Metabolite (1)

FGFR (1)

Fluorescent Dye (1)

Fungal (5)

Glucosidase (2)

Histone Methyltransferase (1)

HIV (1)

Insulin Receptor (1)

Isotope-Labeled Compounds (1)

JAK (3)

Monoamine Oxidase (2)

p38 MAPK (1)

Parasite (10)

PDGFR (1)

Phosphatase (74)

Phosphodiesterase (PDE) (1)

Phospholipase (1)

PKA (1)

PKC (1)

PTEN (2)

Reverse Transcriptase (3)

SARS-CoV (2)

SHP2 (9)

Sirtuin (2)

Src (6)

STAT (1)

Tie (2)

Topoisomerase (3)

Trk Receptor (1)

VEGFR (1)

Xanthine Oxidase (1)

By Research Areas:

Cancer (45)

Cardiovascular Disease (6)

Endocrinology (4)

Infection (12)

Inflammation/Immunology (10)

Metabolic Disease (34)

Neurological Disease (8)

115

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

*EGFR Protein Tyrosine* Kinase Substrate**	EGFR	Cancer
EGFR Protein Tyrosine Kinase Substrate is a EGFR protein tyrosine kinase substrate.

MSI-1436 lactate 1 Publications Verification Trodusquemine lactate; Aminosterol-1436 lactate	Phosphatase	Endocrinology
MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC₅₀ of 1 μM, 200-fold preference over TCPTP (IC₅₀ of 224 μM).

Suramin sodium salt Maximum Cited Publications 13 Publications Verification Suramin hexasodium salt	Phosphatase Sirtuin Reverse Transcriptase Topoisomerase SARS-CoV Parasite Apoptosis	Infection Cardiovascular Disease Cancer
Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor . Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC₅₀=297 nM), SirT2 (IC₅₀=1.15 μM), and SirT5 (IC₅₀=22 μM) . Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC₅₀=5 μM) . Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor . Suramin sodium salt efficiently inhibits IP5K and is an antiparasitic, anti-neoplastic and anti-angiogenic agent .

Suramin	Phosphatase Sirtuin Reverse Transcriptase Topoisomerase SARS-CoV Parasite Apoptosis	Infection Cardiovascular Disease Cancer
Suramin is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor . Suramin is a potent inhibitor of sirtuins: SirT1 (IC₅₀=297 nM), SirT2 (IC₅₀=1.15 μM), and SirT5 (IC₅₀=22 μM) . Suramin is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC₅₀=5 μM) . Suramin is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor .Suramin efficiently inhibits IP5K and is an antiparasitic, anti-neoplastic and anti-angiogenic agent .

MSI-1436 Trodusquemine; Aminosterol-1436	Phosphatase	Endocrinology
MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC₅₀ of appr 1 μM, 200-fold preference over TCPTP (IC₅₀, 224 μM).

[pTyr5] EGFR (988-993)	Phosphatase	Others
[pTyr5] EGFR (988-993) is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). [pTyr5] EGFR (988-993) is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B) .

CGP 53716	Others	Inflammation/Immunology
CGP 53716 is a potent protein tyrosine kinase inhibitor. CGP 53716 has selective activity of platelet-derived growth factor (PDGF) receptor. CGP 53716 can be used in the study of disease induced by abnormal cell proliferation induced by PDGF receptor activation .

[pTyr5] EGFR (988-993) (TFA)	Phosphatase	Others
[pTyr5] EGFR (988-993) TFA is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). [pTyr5] EGFR (988-993) TFA is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B) .

Morin 3-O-β-D-glucopyranoside	Reverse Transcriptase HIV Xanthine Oxidase	Infection Cardiovascular Disease Cancer
Morin 3-O-β-D-glucopyranoside is a natural flavonoid with antifungal, anticancer and antioxidant activities. Morin 3-O-β-D-glucopyranoside inhibits reverse transcriptase, protein-tyrosine kinase and xanthine oxidase, and also shows anti-HIV, antiarteriosclerotic, and superoxide scavenging activities .

DPM-1001	Phosphatase	Metabolic Disease
DPM-1001 is a potent, specific, orally active and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC₅₀ of 100 nM. DPM-1001 is an analog of the specific PTP1B inhibitor MSI-1436. DPM-1001 has anti-diabetic property .

DPM-1001 trihydrochloride	Phosphatase	Metabolic Disease
DPM-1001 trihydrochloride is a potent, specific, orally active and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC₅₀ of 100 nM. DPM-1001 trihydrochloride is an analog of the specific PTP1B inhibitor MSI-1436. DPM-1001 trihydrochloride has anti-diabetic property .

Abl Cytosolic Substrate Abltide	Bcr-Abl	Cancer
Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ). Abl Protein Tyrosine Kinase (AbI) is a truncated form of the v-AbI Protein Tyrosine Kinase, a partner in the Gag-Abl fusion protein of the Abelson murine leukemia virus .

Adrixetinib	c-Met/HGFR	Cancer
Adrixetinib is an inhibitor of protein tyrosine kinase with antineoplastic activity .

(Rac)-RK-682	Phosphatase	Cancer
(Rac)-RK-682, a racemate of RK-682, is a protein tyrosine phosphatases (PTPases) inhibitor. (Rac)-RK-682 inhibits protein tyrosine phosphatase 1B (PTP-1B), low molecular weight protein tyrosine phosphatases (LMW-PTP), and cell division cycle 25B (CDC-25B) with IC₅₀s of 8.6 μM, 12.4 μM, and 0.7 μM, respectively .

Tyrosine kinase-IN-4	c-Met/HGFR	Cancer
Tyrosine kinase-IN-4 (EXAMPLE 107) is a protein tyrosine kinase inhibitor .

Adrixetinib TFA	Others	Cancer
Adrixetinib (TFA) is an inhibitor of protein tyrosine kinase with antineoplastic activity .

TCS 401 2 Publications Verification	Phosphatase	Metabolic Disease
TCS 401 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B).

PTP inhibitor 1	Phosphatase	Cancer
PTP inhibitor 1 is a protein tyrosine phosphatase (PTP) inhibitor, with anti-angiogenic effect .

JTT 551
JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with K_is of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase), respectively; JTT 551 can be used in the research of type 2 diabetes mellitus.

Sodium orthovanadate 5 Publications Verification	Phosphatase	Cancer
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.

4-(Bromoacetyl)phenoxyacetic acid	Phosphatase	Others
4-(Bromoacetyl)phenoxyacetic acid (PTP inhibitor III) is a protein tyrosine phosphatase (PTP) inhibitor .

PTP1B-IN-21	Phosphatase	Metabolic Disease
PTP1B-IN-21 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC₅₀=1.56 μM) over the highly homologous *T-cell protein tyrosine* phosphatase (TCPTP; IC₅₀**>100 μM), which is a key target for type 2 diabetes inhibition .

7-BIA 1 Publications Verification	Phosphatase	Neurological Disease
7-BIA is a *receptor-type protein tyrosine* phosphatase D (PTPRD) inhibitor with an IC₅₀** of ~1-3 μM .

Ginsenoside Ra1	Others	Cardiovascular Disease
Ginsenoside Ra1 is a component from ginseng, inhibits protein tyrosine kinase (PTK) activation induced by hypoxia/reoxygenation .

Momordicoside A
Momordicoside A is isolated from Momordica charantia L. Momordicoside A has the inhibitory effect on protein tyrosine phosphatase (PTP1B) .

PTP1B-IN-20	Phosphatase	Metabolic Disease
PTP1B-IN-20 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC₅₀=1.05 μM) over the highly homologous *T-cell protein tyrosine* phosphatase (TCPTP; IC₅₀**=78.0 μM), which is a key target for type 2 diabetes inhibition .

LMPTP inhibitor 1 dihydrochloride	Phosphatase	Metabolic Disease
LMPTP INHIBITOR 1 (dihydrochloride) is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC₅₀ of 0.8 μM LMPTP-A.

LMPTP inhibitor 1 hydrochloride	Phosphatase	Metabolic Disease
LMPTP inhibitor 1 hydrochloride is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC₅₀ of 0.8 μM LMPTP-A.

LMPTP inhibitor 1	Phosphatase	Metabolic Disease
LMPTP inhibitor 1 is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC₅₀ of 0.8 μM LMPTP-A.

ML120 analog 1	Phosphatase	Cancer
ML120 analog 1 (compound 1) is a competitive inhibitor with a K_i of 0.69 μM for *Hematopoietic protein tyrosine* phosphatase (HePTP)** .

PTP1B-IN-2 3 Publications Verification	Phosphatase	Metabolic Disease
PTP1B-IN-2 is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC₅₀ of 50 nM.

Lck-IN-1	Src	Inflammation/Immunology
Lck-IN-1 is a potent lymphocyte protein tyrosine kinase (Lck) inhibitor extracted from patent WO2007013673A1, example 48 .

Methyl pseudolarate B	Phosphatase	Metabolic Disease
Methyl pseudolarate B, a natural diterpenoid, is a protein tyrosine phosphatase 1B (PTP1B) (Phosphatase) inhibitor with an IC₅₀ value of 10.9 μM .

Licoflavone A 1 Publications Verification	Phosphatase	Neurological Disease
Licoflavone A is a flavonoid isolated from the roots of Glycyrrhiza uralensis, inhibits protein tyrosine phosphatase-1B (PTP1B), with an IC₅₀ of 54.5 μM .

BVT948 1 Publications Verification	Phosphatase Cytochrome P450 Histone Methyltransferase	Cancer
BVT948 is a protein tyrosine phosphatase (PTP) inhibitor which can also inhibit several cytochrome P450 (P450) isoforms and lysine methyltransferase SETD8 (KMT5A).

MY10	Phosphatase	Neurological Disease
MY10 is a potent and orally active *receptor protein tyrosine* phosphatase (RPTPβ/ζ)** inhibitor. MY10 attenuates binge-like ethanol consumption and ethanol reward .

ST271	Phospholipase	Others
ST271 is a potent inhibitor of protein tyrosine kinase (PTK), inhibits phospholipase D activation stimulated by fMet-Leu-Phe and PAF, with IC₅₀s of 6.7 and 9 μM, respectively.

Isotanshinone IIA	Phosphatase	Metabolic Disease
Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC₅₀ 0f 11.4 μM.

3,5-Difluoro-L-tyrosine	Phosphatase	Others
3,5-Difluoro-L-tyrosine is a functional, tyrosinase-resistant mimetic of tyrosine. 3,5-Difluoro-L-tyrosine can be used to analyze the substrate specificity of protein tyrosine phosphatases (PTPs) .

Risvodetinib IkT-148009	c-Met/HGFR	Cancer
Risvodetinib is a potent protein tyrosine kinase inhibitor. Risvodetinib involves in synthesis of Abelson protein kinases (c-Abl1, c-Abl2, and c-kit) inhibitor .

SHP844	SHP2	Cancer
SHP844 is a SHP2 inhibitor with the IC₅₀ of 18.9 µM. SHP2 is a protein tyrosine phosphatase (PTP) that regulates tyrosine phosphorylation levels and is involved in cell proliferation, differentiation and survival .

VE-PTP-IN-1	Others	Cancer
VE-PTP-IN-1 (compound 2) is a weakly acidic and selective inhibitor of *vascular endothelial protein tyrosine* phosphatase (VE-PTP**).VE-PTP-IN-1 is assocaited with vascular homeostasis and angiogenesis.

Licochalcone C 2 Publications Verification	Glucosidase	Metabolic Disease
Licochalcone C could inhibit α-glucosidase, with IC₅₀s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively.

Sodium stibogluconate 4 Publications Verification Stibogluconate trisodium nonahydrate	Phosphatase Parasite SHP2	Cancer
Sodium stibogluconate (Stibogluconate trisodium nonahydrate) is a potent inhibitor of protein tyrosine phosphatase. Sodium stibogluconate inhibits 99% of SHP-1, SHP-2 and PTP1B activity at 10, 100, 100 μg/mL, respectively.

(E,E)-RAMB4	Phosphatase	Metabolic Disease
(E,E)-RAMB4 is a potent and selective *potent protein tyrosine* phosphatase-1B (PTP1B)** inhibitor extracted from patent CN103626692A, example 1 .

EGF Receptor Substrate 2 (Phospho-Tyr5)	Phosphatase	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

Cat. No.	Product Name

HY-L016

Protein Tyrosine Kinase Compound Library

1055 compounds

Protein tyrosine kinases (PTKs) are key signaling molecules and important drug targets. Two classes of PTKs are present in cells: the transmembrane receptor PTKs (RTKs) and the nonreceptor PTKs. The RTK family includes the receptors for insulin and for many growth factors, such as EGFR, FGFR, PDGFR, VEGFR, and NGFR. RTKs are transmembrane glycoproteins that are activated by the binding of their ligands, and they transduce the extracellular signal to the cytoplasm by phosphorylating tyrosine residues on the receptors themselves (autophosphorylation) and on downstream signaling proteins. Their principal functions of PTKs involve the regulation of multicellular aspects of the organism. Cell to cell signals concerning growth, differentiation, adhesion, motility, and death are frequently transmitted through tyrosine kinases. In humans, tyrosine kinases have been demonstrated to play significant roles in the development of many disease states, including diabetes and cancers.

MCE designs a unique collection of 1055 compounds that act as a useful tool for PTKs-related drug screening and disease research.

HY-L081

Phosphatase Inhibitor Library

132 compounds

Protein phosphorylation is a key post-translational modification underlying the regulation of many cellular processes. Phosphatases and kinases contribute to the regulation of protein phosphorylation homeostasis in the cell. This reversible regulation of protein phosphorylation is critical for the proper control of a wide range of cellular activities, including cell cycle, proliferation and differentiation, metabolism, cell-cell interactions, etc.

Protein phosphatases have evolved in separate families that are structurally and mechanistically distinct. Based on substrate specificity and functional diversity, protein phosphatases are classified into two superfamilies: Protein serine/threonine phosphatases and Protein tyrosine phosphatases. Ser/Thr phosphatases are metalloenzymes belonging to two major gene families termed PPP (phosphoprotein phosphatase) and PPM (metal-dependent protein phosphatases), whereas protein tyrosine phosphatases (PTPs) belong to distinct classes of enzymes that utilize a phospho-cysteine enzyme intermediate as a part of their catalytic action.

MCE supplies a unique collection of 132 phosphatase inhibitors that mainly targeting protein tyrosine phosphatases (PTPs) and serine/threonine-specific protein phosphatases. MCE Phosphatase Inhibitor Library is a useful tool for phosphatase drug discovery and related research.

Cat. No.	Product Name	Type

HY-D2204

SHP1-IN-1	Fluorescent Dyes/Probes
SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe ³⁺ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM) .

Cat. No.	Product Name	Type

HY-D0852

Sodium orthovanadate 5 Publications Verification	Biochemical Assay Reagents
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.

HY-116022A

4-Nitrophenyl phosphate disodium hexahydrate 2 Publications Verification p-Nitrophenyl phosphate disodium hexahydrate	Biochemical Assay Reagents
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .

HY-E70189

Tyrosylprotein Sulfotransferase 1 EC:2.8.2.20; TPST1; 1TPST-1	Enzyme Substrates
Tyrosylprotein Sulfotransferase 1 (EC:2.8.2.20, TPST1, 1TPST-1) enables protein homodimerization activity and protein-tyrosine sulfotransferase activity .

Cat. No.	Product Name	Target	Research Area

HY-P2503

EGFR Protein Tyrosine Kinase Substrate

EGFR Cancer

EGFR Protein Tyrosine Kinase Substrate is a EGFR protein tyrosine kinase substrate.

HY-P5426

*Abl protein tyrosine* kinase substrate**	Peptides	Others
Abl protein tyrosine kinase substrate is a biological active peptide. (Abltide is a peptide substrate for Abl Kinase (Abl protein tyrosine kinase), a partner in the gag-Abl fusion protein of the Abelson murine leukemia virus. Used in Western blot and kinase assay.)

HY-P1799

[pTyr5] EGFR (988-993)	Phosphatase	Others
[pTyr5] EGFR (988-993) is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). [pTyr5] EGFR (988-993) is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B) .

HY-P1799A

[pTyr5] EGFR (988-993) (TFA)	Phosphatase	Others
[pTyr5] EGFR (988-993) TFA is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). [pTyr5] EGFR (988-993) TFA is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B) .

HY-P1785

Abl Cytosolic Substrate Abltide	Bcr-Abl	Cancer
Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ). Abl Protein Tyrosine Kinase (AbI) is a truncated form of the v-AbI Protein Tyrosine Kinase, a partner in the Gag-Abl fusion protein of the Abelson murine leukemia virus .

HY-P5996

MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2	Peptides	Others
MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2 is a protein tyrosine phosphatase fluorogenic substrate that can be detected at 393 nm (with excitation at 325 nm) .

HY-P0320

EGF Receptor Substrate 2 (Phospho-Tyr5)	Phosphatase	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

HY-P0320A

EGF Receptor Substrate 2 (Phospho-Tyr5) (TFA)	Phosphatase Biochemical Assay Reagents	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

HY-P0320B

EGF Receptor Substrate 2 (Phospho-Tyr5) (acetate)	Phosphatase Biochemical Assay Reagents	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

HY-P3787

Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2	Peptides	Metabolic Disease
Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2 is the SH2 domain ligand. SH2 domains participate in protein tyrosine kinase (PTK)-mediated cellular signal .

HY-P3743

p60c-src Substrate	Peptides	Others
p60c-src Substrate is an efficient and specific substrate for p60c-src protein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides .

Cat. No.	Product Name

HY-K0022

Phosphatase Inhibitor Cocktail II 315+ Cited Publications
Phosphatase Inhibitor Cocktail II effectively inhibits acid and alkaline phosphatases as well as protein tyrosine phosphatases(PTPs).

Species:	Human (34) Rhesus Macaque (1) Rat (1) Mouse (3) Cynomolgus (2) Rabbit (1)
Tag:	His (24) Tag Free (5) Avi (1) GST (12) Fc (1) Flag (4)
Source:	HEK293 (15) Sf9 insect cells (15) E. coli (11)

Cat. No.	Compare	Product Name	Species	Source

HY-P71141

	*SHP-1 Protein, Human (His)* tyrosine-protein Phosphatase Non-Receptor Type 6; Hematopoietic Cell protein-tyrosine Phosphatase; protein-tyrosine Phosphatase 1C; PTP-1C; protein-tyrosine Phosphatase SHP-1; SH-PTP1; PTPN6; HCP; PTP1C	Human	E. coli
	SHP-1 Protein modulates signaling from tyrosine-phosphorylated cell surface receptors, including KIT and EGFR. It enhances the inhibition of mast cell activation via the Lilrb4a receptor. The SH2 regions interact with cellular components to regulate its phosphatase activity. In collaboration with MTUS1, it induces UBE2V2 expression upon angiotensin II stimulation. SHP-1 plays a crucial role in hematopoiesis. SHP-1 Protein, Human (His) is the recombinant human-derived SHP-1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of SHP-1 Protein, Human (His) is 299 a.a., with molecular weight of ~33.0 kDa.

HY-P78603

	*PTK7 Protein, Rabbit (HEK293, His)* PTK7; CCK4; CCK-4; tyrosine-protein kinase-like 7; protein-tyrosine kinase 7; protein-tyrosine kinase 7	Rabbit	HEK293
	The PTK7 protein is an inactive tyrosine kinase that plays a key role in both non-canonical and canonical Wnt signaling pathways. Effects include cell adhesion, migration, polarity, proliferation, actin cytoskeleton reorganization, and apoptosis. PTK7 Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived PTK7 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of PTK7 Protein, Rabbit (HEK293, His) is 582 a.a., with molecular weight of approximately 110 kDa.

HY-P78619

	*PTK7 Protein, Rat (HEK293, His)* PTK7; CCK4; CCK-4; tyrosine-protein kinase-like 7; protein-tyrosine kinase 7; protein-tyrosine kinase 7	Rat	HEK293
	The PTK7 protein is predicted to mediate cell adhesion molecule binding and play critical roles in a variety of cellular processes, including actin cytoskeleton reorganization and regulation of the canonical Wnt signaling pathway. It affects animal organ development, axis elongation, and epithelial morphogenesis. PTK7 Protein, Rat (HEK293, His) is the recombinant rat-derived PTK7 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of PTK7 Protein, Rat (HEK293, His) is 673 a.a., with molecular weight of 95-130 kDa.

HY-P78761

	*PTK7 Protein, Mouse (HEK293, His)* PTK7; CCK4; CCK-4; tyrosine-protein kinase-like 7; protein-tyrosine kinase 7; protein-tyrosine kinase 7	Mouse	HEK293
	Ptk7 Protein is a cell surface receptor that plays a crucial role in regulating cell migration and tissue development. Dysregulation of Ptk7 Protein has been associated with various diseases, including cancer and developmental disorders. Targeting Ptk7 Protein may offer potential therapeutic interventions in these conditions by modulating cell migration, inhibiting tumor growth, and promoting normal tissue development. PTK7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PTK7 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of PTK7 Protein, Mouse (HEK293, His) is 674 a.a., with molecular weight of 83-130 kDa.

HY-P702726

	*Brk/PTK6 Protein, Human (sf9, His, GST)* PTK6; PTK6 protein tyrosine kinase 6; protein-tyrosine kinase 6; BRK; breast tumor kinase; protein-tyrosine kinase BRK; tyrosine-protein kinase BRK; FLJ42088	Human	Sf9 insect cells

HY-P78573

	*PTK7 Protein, Cynomolgus/Rhesus macaque (HEK293, His)* PTK7; CCK4; CCK-4; tyrosine-protein kinase-like 7; protein-tyrosine kinase 7; protein-tyrosine kinase 7	Cynomolgus;Rhesus Macaque	HEK293
	The PTK7 protein is an inactive tyrosine kinase that plays a key role in both non-canonical and canonical Wnt signaling pathways. Effects include cell adhesion, migration, polarity, proliferation, actin cytoskeleton reorganization, and apoptosis. PTK7 Protein, Cynomolgus/Rhesus macaque (HEK293, His) is the recombinant cynomolgus, Rhesus Macaque-derived PTK7 protein, expressed by HEK293 , with C-His labeled tag. The total length of PTK7 Protein, Cynomolgus/Rhesus macaque (HEK293, His) is 674 a.a., with molecular weight of 90-110 kDa.

HY-P71245

	*PTP4A2 Protein, Human (His)* protein tyrosine phosphatase type IVA 2; PTP4A2; HU-PP-1; OV-1; PTP(CAAXII); protein-tyrosine phosphatase 4a2; protein-tyrosine phosphatase of regenerating liver 2; PRL-2	Human	E. coli
	The PTP4A2 protein is an influential tyrosine phosphatase that stimulates G1 to S phase progression and contributes to cell cycle regulation. Notably, it promotes tumorigenesis, revealing its involvement in cancer development. PTP4A2 Protein, Human (His) is the recombinant human-derived PTP4A2 protein, expressed by E. coli , with C-6*His labeled tag. The total length of PTP4A2 Protein, Human (His) is 167 a.a., with molecular weight of ~20 kDa.

HY-P701970

	*PTPRG Protein, Human* PTPRG; Receptor-type tyrosine-protein phosphatase gamma; protein-tyrosine phosphatase gamma; R-PTP-gamma	Human	E. coli
	PTPRG protein, also known as G-type protein tyrosine phosphatase receptor, is characterized by its tyrosine phosphatase activity. As a member of the protein tyrosine phosphatase (PTP) family, PTPRG is involved in the dephosphorylation of tyrosine residues in target proteins. PTPRG Protein, Human is the recombinant human-derived PTPRG protein, expressed by E. coli , with tag free. The total length of PTPRG Protein, Human is 311 a.a., .

HY-P701971

	*PTPRG Protein, Human (His)* PTPRG; Receptor-type tyrosine-protein phosphatase gamma; protein-tyrosine phosphatase gamma; R-PTP-gamma	Human	E. coli
	PTPRG protein, also known as G-type protein tyrosine phosphatase receptor, is characterized by its tyrosine phosphatase activity. As a member of the protein tyrosine phosphatase (PTP) family, PTPRG is involved in the dephosphorylation of tyrosine residues in target proteins. PTPRG Protein, Human (His) is the recombinant human-derived PTPRG protein, expressed by E. coli , with N-6*His labeled tag. The total length of PTPRG Protein, Human (His) is 311 a.a., .

HY-P75470

	*Brk Protein, Human (sf9, GST)* protein-tyrosine kinase 6; SRC-related intestinal kinase; Ptk6; Sik	Human	Sf9 insect cells
	Brk is a nonreceptor tyrosine protein kinase that regulates signaling pathways critical for epithelial tissue differentiation, normal maintenance, and tumor growth. Context-dependent functions involve a variety of substrates, including RNA-binding proteins, transcription factors, and signaling molecules. Brk Protein, Human (sf9, GST) is the recombinant human-derived Brk protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of Brk Protein, Human (sf9, GST) is 451 a.a., with molecular weight of ~70 kDa.

HY-P72856

	*Brk Protein, Mouse (sf9, His-GST)* protein-tyrosine kinase 6; SRC-related intestinal kinase; Ptk6; Sik	Mouse	Sf9 insect cells
	Brk protein is a non-receptor tyrosine protein kinase that regulates signaling pathways critical for epithelial differentiation and tumor growth. Its context-dependent functions involve phosphorylating substrates such as RNA-binding proteins, transcription factors, and signaling molecules. Brk Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived Brk protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of Brk Protein, Mouse (sf9, His-GST) is 451 a.a., with molecular weight of ~66 kDa.

HY-P77255

TPST1 Protein, Human (HEK293, His)

protein-tyrosine sulfotransferase 1; Tyrosylprotein sulfotransferase 1; TPST-1
Human HEK293

HY-P701655

	*TXK Protein, Human (Sf9, GST)* TXK; tyrosine-protein kinase TXK; protein-tyrosine kinase 4; Resting lymphocyte kinase	Human	Sf9 insect cells
	TXK protein is a non-receptor tyrosine kinase that cooperates with ITK to regulate adaptive immune responses. TXK is activated by the T cell receptor (TCR) and is phosphorylated at Tyr-420 after being recruited to the cell membrane, affecting the development, function and differentiation of T cells. TXK Protein, Human (Sf9, GST) is the recombinant human-derived TXK protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of TXK Protein, Human (Sf9, GST) is 526 a.a., .

HY-P701688

	*FRK Protein, Human (Sf9, GST)* FRK; tyrosine-protein kinase FRK; FYN-related kinase; Nuclear tyrosine protein kinase RAK; protein-tyrosine kinase 5	Human	Sf9 insect cells
	FRK protein is a non-receptor tyrosine protein kinase that acts as a negative regulator of cell proliferation by positively regulating PTEN protein stability. Through phosphorylation of PTEN on “Tyr-336”, FRK may prevent PTEN ubiquitination and degradation by reducing its binding to NEDD4. FRK Protein, Human (Sf9, GST) is the recombinant human-derived FRK protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of FRK Protein, Human (Sf9, GST) is 504 a.a., .

HY-P700618

	*SHP-2 Protein, Human (T253M, Q257L, His)* protein tyrosine phosphatase, non-receptor type 11; Noonan syndrome 1 , NS1; tyrosine-protein phosphatase non-receptor type 11; BPTP3; PTP2C; SH PTP2; SHP 2; SHP2; PTP-2C; protein tyrosine phosphatase-2; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; CFC; NS1; PTP-1D; SH-PTP2; SH-PTP3; MGC14433	Human	E. coli
	The SHP-2 protein is a key player downstream of the receptor and cytoplasmic protein tyrosine kinases, facilitating signal transduction from the cell surface to the nucleus. It actively regulates the MAPK pathway and dephosphorylates key substrates, including GAB1, ARHGAP35, EGFR, ROCK2 ("Tyr-722"), and CDC73. SHP-2 Protein, Human (T253M, Q257L, His) is the recombinant human-derived SHP-2 protein, expressed by E. coli , with N-6*His labeled tag and T253M, Q257L, , , mutation. The total length of SHP-2 Protein, Human (T253M, Q257L, His) is 592 a.a., with molecular weight of 70-75 kDa.

HY-P70552

	*VEGFR-2 Protein, Human (HEK293, His)* 1 Publications Verification Vascular endothelial growth factor receptor 2; KDR; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; protein-tyrosine kinase receptor flk-1; VEGFR2; VEGF R2	Human	HEK293
	VEGFR-2 is a tyrosine-protein kinase of the cell surface receptors of VEGFA, VEGFC, and VEGFD that mediates activation of the MAPK1/ERK2, MAPK3/ERK1, and MAP kinase signaling pathways, as well as the AKT1 signaling pathway. VEGFR-2 can promote the proliferation, survival, migration and differentiation of endothelial cells. Overexpression of VEGFR-2 is associated with the development of tumors. VEGFR-2 Protein, Human (HEK293, His) is the recombinant human-derived VEGFR-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of VEGFR-2 Protein, Human (HEK293, His) is 745 a.a., with molecular weight of 84-140 kDa.

HY-P71421

	*VEGFR-2 Protein, Human (HEK293, His-Avi)* VEGFR2; VEGF R2; Vascular endothelial growth factor receptor 2; KDR; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; protein-tyrosine kinase receptor flk-1	Human	HEK293
	VEGFR-2 protein is a tyrosine protein kinase receptor for VEGFA, VEGFC and VEGFD and is critical in angiogenesis, blood vessel development and embryonic hematopoiesis. It promotes endothelial cell function and actin cytoskeletal reorganization. VEGFR-2 Protein, Human (HEK293, His-Avi) is the recombinant human-derived VEGFR-2 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of VEGFR-2 Protein, Human (HEK293, His-Avi) is 745 a.a., with molecular weight of 120-150 kDa.

HY-P70635

	*VEGFR-2 Protein, Human (745a.a, HEK293, Fc)* Vascular endothelial growth factor receptor 2; KDR; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; protein-tyrosine kinase receptor flk-1; VEGFR2; VEGF R2	Human	HEK293
	VEGFR-2 protein is a tyrosine protein kinase receptor for VEGFA, VEGFC and VEGFD and is critical in angiogenesis, blood vessel development and embryonic hematopoiesis. It promotes endothelial cell function and actin cytoskeletal reorganization. VEGFR-2 Protein, Human (745a.a, HEK293, Fc) is the recombinant human-derived VEGFR-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of VEGFR-2 Protein, Human (745a.a, HEK293, Fc) is 745 a.a., with molecular weight of 150-160 kDa.

HY-P701682

	*FAK1 Protein, Human (Sf9, GST)* PTK2; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; protein phosphatase 1 regulatory subunit 71; PPP1R71; protein-tyrosine kinase 2; p125FAK; pp125FAK	Human	Sf9 insect cells
	FAK1 is a nonreceptor protein tyrosine kinase that coordinates multiple cellular processes. FAK1 Protein, Human (Sf9, GST) is the recombinant human-derived FAK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of FAK1 Protein, Human (Sf9, GST) is 1052 a.a., .

HY-P702717

	*PTK2B Protein, Human (sf9)* PTK2B; PTK2B protein tyrosine kinase 2 beta; FAK2, protein tyrosine kinase 2 beta; protein-tyrosine kinase 2-beta; CADTK; CAKB; PTK; PYK2; RAFTK; FADK 2; CAK-beta; protein kinase B; focal adhesion kinase 2; cell adhesion kinase beta; proline-rich tyrosine kinase 2; calcium-dependent tyrosine kinase; related adhesion focal tyrosine kinase; calcium-regulated non-receptor proline-rich tyrosine kinase; PKB; FAK2; FADK2	Human	Sf9 insect cells

HY-P702757

	*VEGFR-2 Protein, Human (1355a.a, sf9, GST)* KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); FLK1; CD309; VEGFR; VEGFR2; Vascular endothelial growth factor receptor 2; VEGFR-2; Kinase insert domain receptor; protein-tyrosine kinase receptor Flk-1; EC 2.7.10.1; fetal liver kinase-1; soluble VEGFR2; tyrosine kinase growth factor receptor	Human	Sf9 insect cells

HY-P702710

	*EphB2 Protein, Human (sf9, GST)* EPHB2; EPH receptor B2; DRT, EphB2 , EPHT3, ERK; ephrin type-B receptor 2; Hek5; Tyro5; EPH-like kinase 5; eph tyrosine kinase 3; elk-related tyrosine kinase; protein-tyrosine kinase HEK5; tyrosine-protein kinase TYRO5; renal carcinoma antigen NY-REN-47; tyrosine-protein kinase receptor EPH-3; developmentally-regulated Eph-related tyrosine kinase; DRT; EK5; ERK; CAPB; PCBC; EPHT3; MGC87492	Human	Sf9 insect cells

HY-P77167

	*PTK9 Protein, Human* Twinfilin-1; protein A6; protein tyrosine kinase 9; TWF1	Human	E. coli
	PTK9, an actin-binding protein, regulates motility and morphological processes by inhibiting actin polymerization and capping the barbed ends of filaments. It plays a crucial role in clathrin-mediated endocytosis and the distribution of endocytic organelles. PTK9 interacts with G-actin, capping protein (CP), and possibly TWF2 and phosphoinositides, particularly PI(4,5)P2, which down-regulates its activity. Additionally, it interacts with ACTG1. PTK9 Protein, Human is the recombinant human-derived PTK9 protein, expressed by E. coli , with tag free. The total length of PTK9 Protein, Human is 252 a.a., with molecular weight of ~33 kDa.

HY-P701795

	*LTK Protein, Human (Sf9, GST)* LTK; Leukocyte tyrosine kinase receptor; protein tyrosine kinase 1	Human	Sf9 insect cells
	LTK protein, a tyrosine-protein kinase activated by ALKAL1 or ALKAL2 ligands, transduces signals, initiating the MAPK pathway upon ligand binding. It phosphorylates mainly the first tyrosine in the Y-x-x-x-Y-Y motif, with roles in promoting neurite outgrowth, cell survival, and regulating the secretory pathway, impacting ERESs and ER to Golgi transport. LTK Protein, Human (Sf9, GST) is the recombinant human-derived LTK protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of LTK Protein, Human (Sf9, GST) is 415 a.a., .

HY-P77168

	*PTK9 Protein, Human (His-GST)* Twinfilin-1; protein A6; protein tyrosine kinase 9; TWF1	Human	E. coli
	PTK9, an actin-binding protein, regulates motility and morphological processes by inhibiting actin polymerization and capping the barbed ends of filaments. It plays a crucial role in clathrin-mediated endocytosis and the distribution of endocytic organelles. PTK9 interacts with G-actin, capping protein (CP), and possibly TWF2 and phosphoinositides, particularly PI(4,5)P2, which down-regulates its activity. Additionally, it interacts with ACTG1. PTK9 Protein, Human (His-GST) is the recombinant human-derived PTK9 protein, expressed by E. coli , with N-His, N-GST labeled tag. The total length of PTK9 Protein, Human (His-GST) is 252 a.a., with molecular weight of ~50 kDa.

HY-P77169

	*PTP4A2 Protein, Human (GST)* protein tyrosine phosphatase type IVA 2; HU-PP-1; PRL-2; PTPCAAX2	Human	E. coli
	The PTP4A2 protein is an influential tyrosine phosphatase that stimulates G1 to S phase progression and contributes to cell cycle regulation. Notably, it promotes tumorigenesis, revealing its involvement in cancer development. PTP4A2 Protein, Human (GST) is the recombinant human-derived PTP4A2 protein, expressed by E. coli , with N-GST labeled tag. The total length of PTP4A2 Protein, Human (GST) is 166 a.a., with molecular weight of ~45.9 kDa.

HY-P7884

	*CD45 Protein, Mouse (HEK293, His)* rMuReceptor-type tyrosine-protein phosphatase C/CD45, His; B220; CD45 antigen; CD45; CD45R; LCA; L-CA; LY5; protein tyrosine phosphatase, receptor type, C; PTPRC; receptor-type tyrosine-protein phosphatase C	Mouse	HEK293
	CD45/PTPRC Protein, Mouse (HEK 293, His) expresses in HEK293 with a His tag at the N-terminus. CD45 is a transmembrane glycoprotein, expressed on almost all haematopoietic cells except for mature erythrocytes. PTPRC is an essential regulator of T and B cell antigen receptor-mediated activation.

HY-P7887

	*CD45 Protein, Human (552a.a, HEK293, His)* rHuReceptor-type tyrosine-protein phosphatase C/CD45, His; B220; CD45 antigen; CD45; CD45R; LCA; L-CA; LY5; protein tyrosine phosphatase, receptor type, C; PTPRC; receptor-type tyrosine-protein phosphatase C	Human	HEK293
	CD45 Protein, Human (HEK 293, His) is a type 1 transmembrane protein tyrosine phosphatase (PTPase) expressed by all the haematopoietic stem cells (HSCs) except that of erythrocytes and platelets.

HY-P7889

	*PTPRC/CD45RA Protein, Human (HEK293, His)* rHuReceptor-type tyrosine-protein phosphatase C/CD45RA, His ; B220; CD45 antigen; CD45; CD45R; LCA; L-CA; LY5; protein tyrosine phosphatase, receptor type, C; PTPRC; receptor-type tyrosine-protein phosphatase C	Human	HEK293
	Receptor-type tyrosine-protein phosphatase C (PTPRC) is a receptor type PTP and an essential positive regulator of T- and B-cell antigen receptor signaling. PTPRC functions through direct interaction with antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. PTPRC also suppresses JAK kinases as a regulator of cytokine receptor signaling. PTPRC/CD45RA Protein, Human (HEK293, His) is the recombinant human-derived PTPRC/CD45RA protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P7887A

	*CD45 Protein, Human (552a.a, HEK293, C-His)* rHuReceptor-type tyrosine-protein phosphatase C/CD45, His; B220; CD45 antigen; CD45; CD45R; LCA; L-CA; LY5; protein tyrosine phosphatase, receptor type, C; PTPRC; receptor-type tyrosine-protein phosphatase C	Human	HEK293
	Receptor-type tyrosine-protein phosphatase C (PTPRC) is a receptor type PTP and an essential positive regulator of T- and B-cell antigen receptor signaling. PTPRC functions through direct interaction with antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. PTPRC also suppresses JAK kinases as a regulator of cytokine receptor signaling. CD45 Protein, Human (552a.a, HEK293, C-His) is the recombinant human-derived CD45 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of CD45 Protein, Human (552a.a, HEK293, C-His) is 552 a.a., with molecular weight (glycosylation form) of 130-180 kDa.

HY-P7888

	*PTPRC/CD45R0 Protein, Human (HEK293, His)* rHuReceptor-type tyrosine-protein phosphatase C/ CD45R0, His; B220; CD45 antigen; CD45; CD45R; LCA; L-CA; LY5; protein tyrosine phosphatase, receptor type, C; PTPRC; receptor-type tyrosine-protein phosphatase C; CD45R0	Human	HEK293
	PTPRC/CD45R0 Protein, Human (HEK 293, His) expresses in HEK293 with a His tag at the N-terminus. CD45R0 (UCHL1), a member of leucocyte common antigen family, is expressed largely on previously activated or memory T cells.

HY-P702735

	*MAPK1 Protein, Human (Flag, His)* MAPK1; mitogen-activated protein kinase 1; PRKM1, PRKM2; ERK; ERK2; MAPK2; p41mapk; ERK-2; MAPK 2; p42-MAPK; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2; extracellular signal-regulated kinase 2; p38; p40; p41; ERT1; PRKM1; PRKM2; P42MAPK	Human	E. coli

HY-P76556

	*PTPMT1 Protein, Human (His)* Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; PTPMT1; MOSP; PLIP	Human	E. coli
	The PTPMT1 protein is a lipid phosphatase that critically regulates cellular lipid metabolism by dephosphorylating phosphatidylglycerolphosphate (PGP) to form phosphatidylglycerol (PG). This step is critical for the biosynthesis of cardiolipin, a key mitochondrial phospholipid that regulates membrane integrity and mitochondrial activity. PTPMT1 Protein, Human (His) is the recombinant human-derived PTPMT1 protein, expressed by E. coli , with N-His labeled tag. The total length of PTPMT1 Protein, Human (His) is 174 a.a., with molecular weight of ~22 kDa.

HY-P70124

	*CSF1R Protein, Cynomolgus (HEK293, His)* rCynReceptor protein-tyrosine kinase/CSF1R, His; Macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115; CSF1R; FMS	Cynomolgus	HEK293
	CSF1R is colony-stimulating factor receptor, a type I transmembrane protein receptor. Binding of CSF1R to CSF-1 or IL-34 activates a cascade of extracellular pro-cell survival kinases, including PI3K, ERK1/2, and JNK. CSF1R also recruits multiple downstream effector proteins/pathways, including PI3K, Grb2, SFK, Src, PKC, etc. CSF1R is involved in embryonic development and tissue repair and is associated with tumorigenesis and cancer progression. CSF1R Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CSF1R protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CSF1R Protein, Cynomolgus (HEK293, His) is 498 a.a., with molecular weight of 80-120 kDa.

HY-P700511

	*CSF1R Protein, Human (HEK293, His-Flag)* rCynReceptor protein-tyrosine kinase/CSF1R, His; Macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115; CSF1R; FMS	Human	HEK293
	CSF1R protein is ubiquitously found in mononuclear phagocytes, especially macrophages and monocytes, and is involved in a variety of biological processes. It induces the release of proinflammatory chemokines in response to IL34 and CSF1, contributing to innate immunity and inflammation. CSF1R Protein, Human (HEK293, His-Flag) is the recombinant human-derived CSF1R protein, expressed by HEK293 , with C-6*His, C-Flag labeled tag. The total length of CSF1R Protein, Human (HEK293, His-Flag) is 493 a.a., with molecular weight of 57.7 kDa.

HY-P702763

	*NTRK2/TrkB Protein, Human (Biotinylated, sf9, Flag)* NTRK2; neurotrophic tyrosine kinase, receptor, type 2; BDNF/NT-3 growth factors receptor; trk-B; GP145-TrkB/GP95-TrkB; trkB tyrosine kinase; Neural receptor protein-tyrosine kinase (trkB); Tkrb; trkB; TRKB1; RATTRKB1	Human	Sf9 insect cells

HY-P702708

	*EphA7 Protein, Human (sf9)* EPHA7; EPH receptor A7; EphA7; ephrin type-A receptor 7; Hek11; EK11; EHK-3; EPH-like kinase 11; EPH homology kinase 3; Eph homology kinase-3; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3; EHK3; HEK11	Human	Sf9 insect cells

HY-P702720

Janus kinase 2/JAK2 Protein, Human (sf9)

JAK2; Janus kinase 2; tyrosine-protein kinase JAK2; JTK10; JAK-2; Janus kinase 2 (a protein tyrosine kinase); THCYT3
Human Sf9 insect cells

HY-P702702

	TYRO3 Protein, Human (Biotinylated, sf9, Flag) TYRO3; TYRO3 protein tyrosine kinase; RSE; tyrosine-protein kinase receptor TYRO3; Brt; Dtk; Sky; Tif; tyrosine-protein kinase DTK; tyrosine-protein kinase RSE; tyrosine-protein kinase SKY; tyrosine-protein kinase byk; BYK; FLJ16467	Human	Sf9 insect cells

HY-P702721

	*JAK3 Protein, Human (sf9, GST)* JAK3; Janus kinase 3; tyrosine-protein kinase JAK3; JAK 3; JAK3_HUMAN; JAKL; L JAK; leukocyte Janus kinase; LJAK; tyrosine protein kinase JAK3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); JAK-3; L-JAK	Human	Sf9 insect cells

HY-P701102

	*Janus kinase 2/JAK2 Protein, Human (381aa, His)* JAK 2; JAK-2; JAK2; JAK2_HUMAN; Janus Activating Kinase 2; Janus kinase 2 (a protein tyrosine kinase); Janus kinase 2; JTK 10; JTK10; kinase Jak2; OTTHUMP00000043260; THCYT3; tyrosine protein kinase JAK2; tyrosine-protein kinase JAK2	Human	E. coli
	Janus kinase 2/JAK2 Protein, Human is a recombinant human JAK2 expressed in E. coli with a His tag at the N-terminus. JAK2 is a non-receptor tyrosine kinase.

Cat. No.	Product Name	Application	Reactivity

HY-P81307

SHP1 Antibody (YA1044) PTPN6; HCP; PTP1C; tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; protein-tyrosine phosphatase 1C; PTP-1C; protein-tyrosine phosphatase SHP-1; SH-PTP1	WB, IP	Human

HY-P81307A

SHP1 Antibody (YA1045) PTPN6; HCP; PTP1C; tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; protein-tyrosine phosphatase 1C; PTP-1C; protein-tyrosine phosphatase SHP-1; SH-PTP1	WB, IHC-P	Human

HY-P82997

CSK Antibody (YA2742)

CSK; tyrosine-protein kinase CSK; C-Src kinase; protein-tyrosine kinase CYL
WB, IHC-P Human, Mouse, Rat

HY-P81898

SHP2 Antibody (YA1643) PTPN11; PTP2C; SHPTP2; tyrosine-protein phosphatase non-receptor type 11; protein-tyrosine phosphatase 1D; PTP-1D; protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3	WB, IHC-P, IP	Human

HY-P81458

Brk/PTK6 Antibody (YA1203)

PTK6; BRK; protein-tyrosine kinase 6; Breast tumor kinase; tyrosine-protein kinase BRK
IHC-P Human
HY-P82031

PTP1B Antibody (YA1776)

PTPN1; PTP1B; tyrosine-protein phosphatase non-receptor type 1; protein-tyrosine phosphatase 1B; PTP-1B
WB, IHC-F, IHC-P, ICC/IF Human
HY-P81384

RON Antibody (YA1129)

MST1R; PTK8; RON; Macrophage-stimulating protein receptor; MSP receptor; CDw136; protein-tyrosine kinase 8; p185-Ron; CD136
IHC-P Human
HY-P81300

Phospho-PTP1B (Ser352) Antibody (YA1027)

PTPN1; PTP1B; tyrosine-protein phosphatase non-receptor type 1; protein-tyrosine phosphatase 1B; PTP-1B
WB, ICC/IF, IP Human
HY-P81300A

Phospho-PTP1B (Ser378) Antibody (YA1028)

PTPN1; PTP1B; tyrosine-protein phosphatase non-receptor type 1; protein-tyrosine phosphatase 1B; PTP-1B
WB, IHC-P Human

HY-P81643

VEGFR2 Antibody (YA1388) KDR; FLK1; VEGFR2; Vascular endothelial growth factor receptor 2; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; protein-tyrosine kinase receptor flk-1; CD antigen CD309	FC, ELISA	Human

HY-P80645

DUSP1 Antibody DUSP1; CL100; MKP1; PTPN10; VH1; Dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; Mitogen-activated protein kinase phosphatase 1; MAP kinase phosphatase 1; MKP-1; protein-tyrosine phosphatase CL100	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
DUSP1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 39 kDa, targeting to DUSP1. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P80877

PYK2 Antibody (YA682) PTK2B; FAK2; PYK2; RAFTK; protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB, IHC-P	Human
PYK2 Antibody (YA682) is a non-conjugated and Mouse origined monoclonal antibody about 116 kDa, targeting to PYK2 (4B4). It can be used for WB,IHC-P assays with tag free, in the background of Human.

HY-P80816

Phospho-FAK (Tyr576) Antibody PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; protein phosphatase 1 regulatory subunit 71; PPP1R71; protein-tyrosine kinase 2; p125FAK; pp125FAK	WB	Human, Mouse
Phospho-FAK (Tyr576) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 119 kDa, targeting to Phospho-FAK (Tyr576). It can be used for WB assays with tag free, in the background of Human, Mouse.

HY-P83448

PTP4A2 Antibody (YA3193)

protein tyrosine phosphatase type IVA; member 2; HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b
WB, IP Human

HY-P80785

PGP9.5 Antibody UCHL1 / PGP9.5; UCHL1; B220; CD 45; CD45; cd45 antigen; ec3.1.3.48; GP 180; GP180; Human homolog of severe combined immunodeficiency due to PTPRC deficiency; L CA; L-CA; lca; Leukocyte common antigen; LY 5; LY5; protein tyrosine phosphatase receptor type	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
PGP9.5 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 25 kDa, targeting to PGP9.5. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P81156

phospho-ERK1 + 2 (Thr183/Tyr185) Antibody ERK1 + ERK2 (phospho Thr183/Tyr185); phospho-ERK1/MAPK-1/2(Thr183/Tyr185); ERK 1; ERK 2; ERK-2; ERK1; ERK2; ERT1; ERT2; Extracellular signal regulated kinase 1; Extracellular signal regulated kinase 1; Extracellular signal regulated kinase 2; Extracellular signal regulated kinase 2; Extracellular signal-regulated kinase 2; HS44KDAP; HUMKER1A; Insulin stimulated MAP2 kinase; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAP kinase isoform p44; MAPK 1; MAPK 2; MAPK1; MAPK2; MGC20180; Microtubule associated protein 2 kinase; Mitogen activated protein kinase 1; Mitogen activated protein kinase 1; Mitogen activated protein kinase 2; Mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; MK01_MOUSE; p38; p40; p41; p41mapk; p42 MAPK; p42-MAPK; p42MAPK; p42MAPK; p44 ERK1; p44 MAPK; p44ERK1; p44ERK1; p44MAPK; p44MAPK; PRKM 1; PRKM 1; PRKM 2; PRKM 2; PRKM1; PRKM2; protein kinase mitogen activated 1; protein kinase mitogen activated 1; protein kinase mitogen activated 2; protein kinase mitogen activated 2; protein tyrosine kinas.	WB; ELISA; IHC-P; IHC-F; ICC; IF	Human, Mouse(predicted: Rat, Chicken, Dog, Cow, Horse, Rabbit, Guinea Pig)
phospho-ERK1 + 2 (Thr183/Tyr185) Antibody is an unconjugated, approximately 42/44 kDa, rabbit-derived, anti-phospho-ERK1 + 2 (Thr183/Tyr185) polyclonal antibody. phospho-ERK1 + 2 (Thr183/Tyr185) Antibody can be used for: WB, ELISA, IHC-P, IHC-F, ICC, IF expriments in human, mouse, and predicted: rat, chicken, dog, cow, horse, rabbit, guinea pig background without labeling.

HY-P80743

Lck Antibody (YA712) LCK; tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK	WB	Human
Lck Antibody (YA712) is a non-conjugated and Mouse origined monoclonal antibody about 58 kDa, targeting to Lck (3E5). It can be used for WB assays with tag free, in the background of Human.

HY-P80747

Lyn Antibody (YA707) LYN; JTK8; tyrosine-protein kinase Lyn; Lck/Yes-related novel protein tyrosine kinase; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56Lyn	WB	Human
Lyn Antibody (YA707) is a non-conjugated and Mouse origined monoclonal antibody about 59 kDa, targeting to Lyn (1C8). It can be used for WB assays with tag free, in the background of Human.

HY-P83458

ABL2 Antibody (YA3203) ABL2; ABLL; ARG; Abelson tyrosine-protein kinase 2; Abelson murine leukemia viral oncogene homolog 2; Abelson-related gene protein; tyrosine-protein kinase ARG	WB, FC	Human, Mouse, Rat

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