PTP1B-IN-18
PTP1B-IN-18 is an orally active complete mixed type protein tyrosine phosphatase 1B (PTP1B) inhibitor with a Ki of 35.2 μM. PTP1B-IN-18 can be used for type 2 diabetes research.
For research use only. We do not sell to patients.
- CAS No.: 2848581-84-8
- Formula: C26H19N3O4S
- Molecular Weight:469.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
ki: 35.2 μM (PTP1B)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female Wistar rats weighing 200-250 g (type 2 diabetic rat model)[1]
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Dosage:100 mg/kg
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Administration:Oral administration; single administration
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Result:Showed hypoglycemic effect under physiological conditions.
Chemical Information
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CAS No. 2848581-84-8
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Molecular Weight 469.51
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Formula C26H19N3O4S
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SMILES
O=C(NC1=CC=C(C=C1)C(O)=O)CSC2=NC3=C(N2)C=CC(OC4=CC=C5C=CC=CC5=C4)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)