PTP4A2 Antibody (YA3193)
(Synonyms: protein tyrosine phosphatase type IVA; member 2; HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b)PTP4A2 Antibody (YA3193) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PTP4A2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IP
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Reactivity :
Human
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:20 |
Product Details
PTP4A2 Antibody (YA3193) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PTP4A2.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 19 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 19 kDa
A synthetic peptide of human PTP4A2/PRL2
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PTP4A2 is a Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB
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Subcellular Localization
Cell membrane; Early endosome; Cytoplasm
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Expression
Tissue_specificity:Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue -
Isoforms & Post-Translational Modification
Q12974 has 4 isomers: Q12974-1: 19127 Da (predicted); Q12974-2: 9241 Da (predicted); Q12974-3: 15669 Da (predicted); Q12974-4: 16367 Da (predicted).
Farnesylated. Farnesylation is required for membrane targeting and for interaction with RABGGTB. Unfarnesylated forms are redirected to the nucleus and cytosol -
Subunit
In contrast to PTP4A1 and PTP4A3, does not interact with tubulin. Interacts with RABGGTB
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SwissProt ID
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Synonyms
protein tyrosine phosphatase type IVA; member 2; HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b
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Research Field
Cell Biology
Documentation
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