1. Anti-infection
    Metabolic Enzyme/Protease
  2. Enterovirus
    Phosphatase
  3. Prunin

Prunin (Synonyms: Naringenin 7-0-glucoside)

Cat. No.: HY-N1549
Handling Instructions

Prunin is a potent inhibitor of human enterovirus A71 (HEVA71). Prunin shows strong inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), with an IC50 of 5.5 µM.

For research use only. We do not sell to patients.

Prunin Chemical Structure

Prunin Chemical Structure

CAS No. : 529-55-5

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Description

Prunin is a potent inhibitor of human enterovirus A71 (HEVA71). Prunin shows strong inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), with an IC50 of 5.5 µM[1][2].

In Vitro

Prunin exhibited dose-dependent inhibitory activity against ONOO--mediated tyrosine nitration and stimulated glucose uptake by decreasing PTP1B expression level in insulin-resistant HepG2 cells. Prunin shows significant inhibitory activity against α-glucosidase, with an IC50 of 317 ± 2.12 µM[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

434.39

Formula

C₂₁H₂₂O₁₀

CAS No.

529-55-5

SMILES

O=C1C[[email protected]@H](C2=CC=C(O)C=C2)OC3=CC(O[[email protected]]4[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]@H](CO)O4)O)O)O)=CC(O)=C13

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

PruninNaringenin 7-0-glucosideEnterovirusPhosphataseRhinovirusHRVHRVsHEVHEVsenterovirusphosphataseinfectionRNAsynthesisanti-diabeticInhibitorinhibitorinhibit

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