1. Protein Tyrosine Kinase/RTK
    JAK/STAT Signaling
  2. EGFR
  3. EGFR Protein Tyrosine Kinase Substrate

EGFR Protein Tyrosine Kinase Substrate 

Cat. No.: HY-P2503
Handling Instructions

EGFR Protein Tyrosine Kinase Substrate is a EGFR protein tyrosine kinase substrate.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

EGFR Protein Tyrosine Kinase Substrate Chemical Structure

EGFR Protein Tyrosine Kinase Substrate Chemical Structure

CAS No. : 945830-38-6

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Description

EGFR Protein Tyrosine Kinase Substrate is a EGFR protein tyrosine kinase substrate.

Molecular Weight

1076.16

Formula

C₄₈H₇₃N₁₁O₁₇

CAS No.

945830-38-6

Sequence Shortening

ADEYLIPQQ

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

EGFR Protein Tyrosine Kinase SubstrateEGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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Product Name:
EGFR Protein Tyrosine Kinase Substrate
Cat. No.:
HY-P2503
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