1. Metabolic Enzyme/Protease
  2. Phosphatase
  3. NSC-87877

NSC-87877 

Cat. No.: HY-18756
Handling Instructions

NSC-87877 is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC50 values of 0.318 μM, 0.355 μM shp2 and shp1, respectively. NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26).

For research use only. We do not sell to patients.

NSC-87877 Chemical Structure

NSC-87877 Chemical Structure

CAS No. : 56990-57-9

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Description

NSC-87877 is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC50 values of 0.318 μM, 0.355 μM shp2 and shp1, respectively[1]. NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26)[2].

IC50 & Target

IC50: 0.318 μM (shp2), 0.355 μM (shp1)[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

459.45

Formula

C₁₉H₁₃N₃O₇S₂

CAS No.

56990-57-9

SMILES

O=S(C1=C2C=CC=NC2=C(O)C(/N=N/C3=CC=C4C=C(S(=O)(O)=O)C=CC4=C3)=C1)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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NSC-87877
Cat. No.:
HY-18756
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NSC-87877

Cat. No.: HY-18756