2. Protein Tyrosine Kinase/RTK Apoptosis
  3. Src Apoptosis
  4. 2-Hydroxy-3-methylanthraquinone

2-Hydroxy-3-methylanthraquinone (compound 1) is a natural compound isolated from a water extract of Hedyotis diffusa WILLD. 2-Hydroxy-3-methylanthraquinone shows inhibitory activity against protein tyrosine kinases v-src and pp60src, and induces growth arrest and apoptosis in the HepG2 cancer cells.

For research use only. We do not sell to patients.

2-Hydroxy-3-methylanthraquinone Chemical Structure

2-Hydroxy-3-methylanthraquinone Chemical Structure

CAS No. : 17241-40-6

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2-Hydroxy-3-methylanthraquinone Related Antibodies

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Description

2-Hydroxy-3-methylanthraquinone (compound 1) is a natural compound isolated from a water extract of Hedyotis diffusa WILLD. 2-Hydroxy-3-methylanthraquinone shows inhibitory activity against protein tyrosine kinases v-src and pp60src, and induces growth arrest and apoptosis in the HepG2 cancer cells[1].

IC50 & Target

55 μM (HepG2 cells)[1]
Molecular Weight

238.24

Formula

C15H10O3
CAS No.
SMILES

O=C1C2=C(C=CC=C2)C(C3=CC(O)=C(C)C=C13)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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2-Hydroxy-3-methylanthraquinone Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Hydroxy-3-methylanthraquinone17241-40-6SrcApoptosisprotein tyrosine kinasesapoptosisHepG2growth arrestInhibitorinhibitorinhibit

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