1. Metabolic Enzyme/Protease
  2. Phosphatase

Isotanshinone IIA 

Cat. No.: HY-N6650
Handling Instructions

Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.

For research use only. We do not sell to patients.

Isotanshinone IIA Chemical Structure

Isotanshinone IIA Chemical Structure

CAS No. : 20958-15-0

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.

IC50 & Target

IC50: 11.4 μM (PTP1B)[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3974 mL 16.9872 mL 33.9743 mL
5 mM 0.6795 mL 3.3974 mL 6.7949 mL
10 mM 0.3397 mL 1.6987 mL 3.3974 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

294.34

Formula

C₁₉H₁₈O₃

CAS No.

20958-15-0

SMILES

O=C1C2=C(C3=C(C=C2)C(C)(C)CCC3)C(C4=C1C(C)=CO4)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Isotanshinone IIA
Cat. No.:
HY-N6650
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Isotanshinone IIA

Cat. No.: HY-N6650