2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. Isotanshinone IIA

Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.

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Isotanshinone IIA Chemical Structure

Isotanshinone IIA Chemical Structure

CAS No. : 20958-15-0

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Isotanshinone IIA Related Antibodies

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Description

Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.

IC50 & Target

IC50: 11.4 μM (PTP1B)[1].
Molecular Weight

294.34

Formula

C19H18O3
CAS No.
Appearance

Solid

Color

Orange to orange red

SMILES

O=C1C2=C(C3=C(C=C2)C(C)(C)CCC3)C(C4=C1C(C)=CO4)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥98.0%

COA (252 KB)

Handling Instructions (2659 KB)
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Isotanshinone IIA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isotanshinone IIA20958-15-0PhosphataseInhibitorinhibitorinhibit

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