2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. PTP1B-IN-17

PTP1B-IN-17 

Cat. No.: HY-144718
Handling Instructions

PTP1B-IN-17 (Compound 45), a potential selective benzimidazole derivative, acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a Ki of 30.2 μM. PTP1B-IN-17 can be used for the research of type 2 diabetes.

For research use only. We do not sell to patients.

PTP1B-IN-17 Chemical Structure

PTP1B-IN-17 Chemical Structure

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Description

PTP1B-IN-17 (Compound 45), a potential selective benzimidazole derivative, acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a Ki of 30.2 μM. PTP1B-IN-17 can be used for the research of type 2 diabetes.

IC50 & Target

Ki: 30.2 μM (PTP1B)[1]
Molecular Weight

469.51

Formula

C26H19N3O4S
SMILES

O=C(NC1=CC=C(C=C1)C(O)=O)CSC2=NC3=C(N2)C=CC(OC4=C5C=CC=CC5=CC=C4)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PTP1B-IN-17PhosphatasePTP1BBenzimidazole derivativesMolecular dynamicsEnzyme inhibitionHypoglycemic effectType 2 diabetesInhibitorinhibitorinhibit

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