Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
187 Results for "
tumor cell membrane
" in MedChemExpress (MCE) Product Catalog:
Products (187)
187 Results for "tumor cell membrane" in MCE Product Catalog:
21
21 Publications Verification
Cat. No.: HY-D0085
CAS No.: 53213-94-8
21
Target:
21
21 Publications Verification
Synonyms: Hyaluronan; Hyaluronate
Category:
Zea mays L. Moisture Plants Endogenous metabolite Human Gut Microbiota Metabolites Polysaccharides Gramineae Cosmetic Research Disease Research Fields Saccharides Cancer
Target:
7
7 Cited Publications
Cat. No.: HY-D1063
CAS No.: 207399-07-3
6
4
4 Cited Publications
Synonyms: Monoaminoethyl phosphate; NSC 254167; O-Phosphoethanolamine
Category:
Natural Products Immune System Disorder Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
3
3 Cited Publications
Cat. No.: HY-N12257
CAS No.: 27220-57-1
Category:
3
3 Cited Publications
Cat. No.: HY-B0984
CAS No.: 13636-18-5
Target:
Research Areas:
Fendiline hydrochloride, a diphenylalkylamine type of antianginal agent, is an L-type calcium channel blocker (IC50 of 17 µM). Fendiline hydrochloride is also a selective K-Ras inhibitor, and has no effect on H-Ras and N-Ras. Fendiline hydrochloride inhibits K-Ras plasma membrane localization (IC50 of 9.64 μM), inhibits K-Ras signal output and blocks the proliferation of pancreatic, colon, lung, and endometrial cancer cell lines expressing oncogenic mutant K-Ras. Fendiline hydrochloride is a STING agonist and is able to inhibit the growth of multiple refractory cold tumors (MC38, CT26 and B16F10) .
3
3 Cited Publications
Cat. No.: HY-B0984A
CAS No.: 13042-18-7
Target:
Research Areas:
Fendiline, a diphenylalkylamine type of antianginal agent, is an L-type calcium channel blocker (IC50 of 17 µM). Fendiline is also a selective K-Ras inhibitor, and has no effect on H-Ras and N-Ras. Fendiline inhibits K-Ras plasma membrane localization (IC50 of 9.64 μM), inhibits K-Ras signal output and blocks the proliferation of pancreatic, colon, lung, and endometrial cancer cell lines expressing oncogenic mutant K-Ras. Fendiline is a STING agonist and is able to inhibit the growth of multiple refractory cold tumors (MC38, CT26 and B16F10) .
3
Category:
Quinones other families Other Diseases Plants Disease Research Fields Naphthalene Quinones Pteris livida Mett.
Target:
3
3
3 Cited Publications
Cat. No.: HY-N1431A
CAS No.: 29479-00-3
2
2 Cited Publications
Cat. No.: HY-P70457
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TACSTD2; Epithelial Glycoprotein-1; Prev. M1S1; membrane Component, Chromosome 1, Surface Marker 1; GA733-1; Gastrointestinal tumor-Associated Antigen GA7331; TROP2; Pancreatic Carcinoma Marker Protein GA7331; tumor-Associated Calcium Signal Transducer 2; cell Surface Glycoprotein TROP2; EGP-1; Truncated TACSTD2; membrane Component Chromosome 1 Surface Marker 1; GA7331; Pancreatic Carcinoma Marker Protein GA733-1; EGP1; Trophoblast cell Surface Antigen 2; GP50; cell Surface Glycoprotein Trop-2; tumor Associated Calcium Signal Transducer 2; 40kD Glycoprotein, Identified By Monoclonal Antibody GA733
Species:
Human
Source:
HEK293
2
2 Cited Publications
Synonyms: (-)-Cephaeline; NSC 32944 free base
1
1 Cited Publications
Cat. No.: HY-16160
CAS No.: 851636-83-4
Research Areas:
Cysmethynil is an Icmt inhibitor(IC50 = 2.4 μM). Cysmethynil inhibites RAS membrane binding and EGF signal transduction. Cysmethynil prevents the cells in the G1 phase and induces autophagy. Cysmethynil inhibits PC3 cells proliferation, has synergistic effect with Paclitaxel (HY-B0015) and Doxorubicin (HY-15142A). Cysmethynil has anti-tumor effects and can be used for solid tumor (such as prostate cancer et al.) research .
1
1 Cited Publications
Cat. No.: HY-P10218
CAS No.: 479482-23-0
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P10218A
Research Areas:
1
Research Areas:
Sodium metavanadate, 99% (Sodium vanadate (V), 99%) is an orally active phosphate structural analog and protein tyrosine phosphatase (PTPases) inhibitor. Sodium metavanadate, 99% mimics phosphate to interfere with phosphoprotein reactions, inhibits GAPDH, Na +/K +-ATPase and microbial membrane ATPase, and acts as a terminal electron acceptor for anaerobic respiration. Sodium metavanadate, 99% induces ROS production, G2/M phase arrest, mitochondrial membrane potential loss and apoptosis in breast cancer cells, and reduces tumor volume in tumor-bearing mice. Sodium metavanadate, 99% also exhibits oral insulin-sensitizing and metabolic regulatory activities, and reduces plasmodium parasitemia levels. Sodium metavanadate, 99% can be used in studies related to cadmium exposure-induced metabolic syndrome, plasmodium infection, breast cancer and type 1 diabetes .
1
1 Cited Publications
Cat. No.: HY-156675A
Purity: 99.34%
Target:
Microtubule/Tubulin Eukaryotic Initiation Factor (eIF) HSP Caspase Reactive Oxygen Species (ROS) Apoptosis
Research Areas:
Plecstatin-1 hydrochloride is a metal complex that drives the aggregation and collapse of the plectin network, and disrupts the cytoskeletal structures of α‑tubulin and F‑actin. Plecstatin-1 hydrochloride triggers oxidative stress, mediates the phosphorylation of eIF2α, and induces molecular features associated with immunogenic cell death, including calreticulin membrane exposure, membrane localization of HSP70/HSP90, ATP secretion, and HMGB‑1 release. Plecstatin-1 hydrochloride induces apoptosis via the intrinsic mitochondrial pathway and exerts anti-invasive activity. Plecstatin-1 hydrochloride inhibits sphere proliferation and reduces clonogenicity in the 3D tumor spheroid model of colon cancer cells. Plecstatin-1 hydrochloride is applicable to relevant research on colorectal cancer .
1
Category:
Infection Triterpenes Animals Terpenoids Marine natural products Other marine organisms Disease Research Fields Cancer
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
