SKF-83566-PEG1-pomalidomide
SKF-83566-PEG1-pomalidomide is an anti-tumor agent and is formed by the covalent connection of SKF-83566 (HY-103430A) (dopamine D1 receptor antagonist) and Pomalidomide (HY-10984) (immunomodulatory agent). SKF-83566-PEG1-pomalidomide can inhibit cancer cells invasion, migration and colony formation. SKF-83566-PEG1-pomalidomide can inhibit tumor growth and angiogenesis in MDA-MB-231 cell chicken embryo chorioallantoic membrane (CAM) xenograft model. SKF-83566-PEG1-pomalidomide can be used for research of breast cancer.
For research use only. We do not sell to patients.
- Formula: C32H31BrN4O5
- Molecular Weight:631.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Dopamine Receptor Isoforms
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Biological Activity
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D1 Receptor |
SKF-83566-PEG1-pomalidomide (Compound 8a) shows IC50 values of 5.5 and 10.13 μM against MDA-MB-231 and HeLa cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 631.52
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Formula C32H31BrN4O5
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SMILES
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C(NCCOC4=C(Br)C=C5CCN(C)CC(C6=CC=CC=C6)C5=C4)=CC=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SKF-83566-PEG1-pomalidomide Related Classifications
HY-180814 Related Classifications
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