2. Others Neuronal Signaling GPCR/G Protein
  3. Drug Derivative Dopamine Receptor
  4. SKF-83566-PEG1-pomalidomide

SKF-83566-PEG1-pomalidomide is an anti-tumor agent and is formed by the covalent connection of SKF-83566 (HY-103430A) (dopamine D1 receptor antagonist) and Pomalidomide (HY-10984) (immunomodulatory agent). SKF-83566-PEG1-pomalidomide can inhibit cancer cells invasion, migration and colony formation. SKF-83566-PEG1-pomalidomide can inhibit tumor growth and angiogenesis in MDA-MB-231 cell chicken embryo chorioallantoic membrane (CAM) xenograft model. SKF-83566-PEG1-pomalidomide can be used for research of breast cancer.

For research use only. We do not sell to patients.

SKF-83566-PEG1-pomalidomide

SKF-83566-PEG1-pomalidomide Chemical Structure

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SKF-83566-PEG1-pomalidomide Related Antibodies

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Description

SKF-83566-PEG1-pomalidomide is an anti-tumor agent and is formed by the covalent connection of SKF-83566 (HY-103430A) (dopamine D1 receptor antagonist) and Pomalidomide (HY-10984) (immunomodulatory agent). SKF-83566-PEG1-pomalidomide can inhibit cancer cells invasion, migration and colony formation. SKF-83566-PEG1-pomalidomide can inhibit tumor growth and angiogenesis in MDA-MB-231 cell chicken embryo chorioallantoic membrane (CAM) xenograft model. SKF-83566-PEG1-pomalidomide can be used for research of breast cancer[1].

IC50 & Target[1]

D1 Receptor

 

In Vitro

SKF-83566-PEG1-pomalidomide (Compound 8a) shows IC50 values of 5.5 and 10.13 μM against MDA-MB-231 and HeLa cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SKF-83566-PEG1-pomalidomide Related Antibodies
Molecular Weight

631.52

Formula

C32H31BrN4O5
SMILES

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C(NCCOC4=C(Br)C=C5CCN(C)CC(C6=CC=CC=C6)C5=C4)=CC=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SKF-83566-PEG1-pomalidomide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SKF-83566-PEG1-pomalidomideDrug DerivativeDopamine ReceptorDrug derivativeInhibitorinhibitorinhibit

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SKF-83566-PEG1-pomalidomide
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