Biotin-NH-PSMA-617
Based on 1 Customer Validation
Biotin-NH-PSMA-617 is a biotin-tagged PSMA-617. PSMA-617 is a small molecule targeting the prostate-specific membrane antigen (PSMA), which is directly expressed by the tumor cells .
For research use only. We do not sell to patients.
- Purity: 98.77%
- Formula: C65H97N13O19S
- Molecular Weight:1396.61
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
PSMA-617 is a PSMA ligand. PSMA-617 shows a significantly improved binding affinity to PSMA as well as a highly efficient internalization into PCa cells. PSMA-617 can be labeled with 68Ga, 177Lu, 111In, and 90Y and, therefore, be used for PET-imaging as well as for radioligand-based therapy[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Appearance Solid
-
Molecular Weight 1396.61
-
Formula C65H97N13O19S
-
Color White to off-white
-
SMILES
O=C(O)[C@H](CCCCNC([C@@H](CC1=CC=C2C=CC=CC2=C1)NC(C3CCC(CNC([C@@H](NC(CN4CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC4)=O)CCCCNC(CCCC[C@@H]5SC[C@]([C@]5([H])N6)([H])NC6=O)=O)=O)CC3)=O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
-
Data Sheet (267 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
[1]. Kratochwil C, et al. Targeted alpha therapy of mCRPC: Dosimetry estimate of 213Bismuth-PSMA-617. Eur J Nucl Med Mol Imaging. 2018;45(1):31-37. [Content Brief]
[2]. Afshar-Oromieh A, et al. The Theranostic PSMA Ligand PSMA-617 in the Diagnosis of Prostate Cancer by PET/CT: Biodistribution in Humans, Radiation Dosimetry, and First Evaluation of Tumor Lesions. J Nucl Med. 2015;56(11):1697-1705. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Biotin-NH-PSMA-617 Related Classifications
HY-141729 Related Classifications
Powered by Bioz