285 Results for "

Cell-penetrating

" in MedChemExpress (MCE) Product Catalog:
Products (285)

285 Results for "Cell-penetrating" in MCE Product Catalog:

261
261 Publications Verification
Cat. No.: HY-P0175
CAS No.: 1236188-16-1
Synonyms: 740YPDGFR; PDGFR 740Y-P
Target:  

PI3K Autophagy

Research Areas:  

Cancer

740 Y-P (740YPDGFR; PDGFR 740Y-P) is a potent and cell-permeable PI3K activator. 740 Y-P readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .
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45
45 Cited Publications
Cat. No.: HY-P0151
CAS No.: 213546-53-3
Target:  

NF-κB

Research Areas:  

Inflammation/Immunology

SN50 is a cell permeable inhibitor of NF-κB translocation.
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28
28 Cited Publications
Cat. No.: HY-100223
CAS No.: 117591-20-5
Purity:  ≥98.0%
Research Areas:  

Inflammation/Immunology

Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID50 of 40 nM for Calpain I in human platelets . Calpeptin is also an inhibitor of cathepsin K .
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17
17 Cited Publications
Cat. No.: HY-P1026
CAS No.: 249537-73-3
Synonyms: VIVIT peptide
NFAT Inhibitor (VIVIT peptide) is an inhibitor of nuclear factor of activated Tcells (NFAT) that selectively inhibits calcineurin-mediated dephosphorylation of NFAT .
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11
11 Cited Publications
Cat. No.: HY-P0069
CAS No.: 1445179-97-4
Synonyms: AM-111; XG-102
Target:  

JNK

Research Areas:  

Others

D-JNKI-1 (AM-111) is a highly potent and cell-permeable peptide inhibitor of JNK.
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9
9 Cited Publications
Cat. No.: HY-12290
CAS No.: 91037-65-9
Purity:  99.93%
Synonyms: RGDS peptide; Fibronectin tetrapeptide
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1.
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9
9 Cited Publications
Cat. No.: HY-P0278
CAS No.: 99896-85-2
Target:  

Integrin

Research Areas:  

Cancer

RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
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9
9 Cited Publications
Cat. No.: HY-P0278A
CAS No.: 2378808-45-6
Target:  

Integrin

Research Areas:  

Cancer

RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins.
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9
9 Cited Publications
Cat. No.: HY-P1430
CAS No.: 592517-80-1
Synonyms: Cell permeable NFAT inhibitor
11R-VIVIT is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. 11R-VIVIT can be used for the research of podocyte and diabetic nephropathy .
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9
9 Cited Publications
Cat. No.: HY-P1430A
Synonyms: Cell permeable NFAT inhibitor TFA
11R-VIVIT TFA is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. 11R-VIVIT TFA can be used for the research of podocyte and diabetic nephropathy .
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8
8 Cited Publications
Cat. No.: HY-P0117
CAS No.: 500992-11-0
Synonyms: Tat-NR2Bct; NA-1
Target:  

iGluR NO Synthase

Research Areas:  

Neurological Disease

Tat-NR2B9c (Tat-NR2Bct; NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy .
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8
8 Cited Publications
Cat. No.: HY-P0117A
CAS No.: 1834571-04-8
Synonyms: Tat-NR2Bct TFA; NA-1 TFA
Target:  

iGluR NO Synthase

Research Areas:  

Neurological Disease

Tat-NR2B9c TFA (Tat-NR2Bct TFA) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c TFA disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c TFA also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy .
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7
7 Cited Publications
Cat. No.: HY-P0122
CAS No.: 1392278-76-0
Synonyms: c(CRGDKGPDC)
Target:  

Integrin

Research Areas:  

Cancer

iRGD peptide is a 9-amino acid cyclic peptide, triggers tissue penetration of agents by first binding to αv-integrins, then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties.
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5
5 Cited Publications
Cat. No.: HY-P0111
CAS No.: 210345-00-9
Synonyms: Z-WE(OMe)HD(OMe)-FMK
Target:  

Caspase Cathepsin

Research Areas:  

Cancer

Z-WEHD-FMK is a potent, cell-permeable and irreversible caspase-1/5 inhibitor. Z-WEHD-FMK also exhibits a robust inhibitory effect on cathepsin B activity (IC50=6 μM). Z-WEHD-FMK can be used to investigate cells for evidence of apoptosis .
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5
5 Cited Publications
Cat. No.: HY-P3229
CAS No.: 1071173-56-2
Target:  

NF-κB

Research Areas:  

Cancer

SN52 is a potent, competitive, and cell-permeable inhibitor of NF-κB2. SN52 is a variant of the SN50 peptide and inhibits the nuclear translocation of p52-RelB heterodimers. SN52 has a strong radiosensitization effect on prostate cancer cells. SN52 can be used for cancer research .
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4
4 Cited Publications
Cat. No.: HY-P0240
CAS No.: 9063-57-4
Tuftsin is a tetrapeptide. Tuftsin is a macrophage/microglial activator.
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3
3 Cited Publications
Cat. No.: HY-W011400
CAS No.: 566914-00-9
Target:  

MyD88

Research Areas:  

Inflammation/Immunology

TLR1 (compound 4a) is a low molecular weight, cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic. TLR1 inhibits IL-1 receptor-mediated responses .
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3
3 Cited Publications
Cat. No.: HY-P1876
CAS No.: 95088-49-6
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

NLS (PKKKRKV) is a nuclear localization signal (NLS) derived from the SV40 large T antigen, which mediates the binding of karyophilic proteins to importin α. NLS (PKKKRKV) serves as a method to enhance nuclear entry in the field of gene transfer research .
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3
3 Cited Publications
Cat. No.: HY-P1876B
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

NLS (PKKKRKV) hydrochloride is the hydrochloride form of NLS (PKKKRKV) (HY-P1876). NLS (PKKKRKV) is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen), that mediates binding of the karyophilic protein to importin α. NLS (PKKKRKV) can function as a method to enhance nuclear entry in the field of gene transfer research .
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3
3 Cited Publications
Cat. No.: HY-P2341
Target:  

LDLR

Research Areas:  

Cancer

Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer .
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