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antioxidant Potential

" in MedChemExpress (MCE) Product Catalog:

183

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1

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8

Biochemical Assay Reagents

4

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98

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12

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W015229
    3-Indolepropionic acid
    5+ Cited Publications

    Indole-3-propionic acid; 3-IPA

    Endogenous Metabolite Reactive Oxygen Species (ROS) Neurological Disease Metabolic Disease
    3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease.
    3-Indolepropionic acid
  • HY-N0411
    β-Carotene
    2 Publications Verification

    Provitamin A; beta-Carotene

    Environmental Pollutants Endogenous Metabolite Reactive Oxygen Species (ROS) Apoptosis Metabolic Disease Cancer
    β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .
    β-Carotene
  • HY-N0321

    trans-Caftaric acid

    Others Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Caftaric acid (trans-Caftaric acid) is a polyphenolic antidiuretic, antioxidant and anti-apoptotic agent that can be hydrolyzed by intestinal microbial esterases. Caftaric acid exerts its antioxidant and potential anti-inflammatory effects mainly through intestinal microbial metabolism. Caftaric acid can reduce renal damage, restore electrolyte balance, renal function indicators and antioxidant enzyme activities in a rat albinism model, and further exert anti-oxidative stress and anti-inflammatory activities .
    Caftaric acid
  • HY-113556
    Sappanone A
    5+ Cited Publications

    Phosphodiesterase (PDE) NF-κB Keap1-Nrf2 Reactive Oxygen Species (ROS) TNF Receptor Nuclear Factor of activated T Cells (NFAT) Akt ERK p38 MAPK NO Synthase Interleukin Related COX JNK Cardiovascular Disease Inflammation/Immunology
    Sappanone A is an orally active homoisoflavone found in sappan L. Sappanone A is a PDE4 and NF-κB inhibitor with anti-inflammatory and antioxidant effect. Sappanone A induces HO-1 expression through activation of Nrf2 pathway. Sappanone A also inhibits RANKL-induced osteoclastogenesis. Sappanone A has great potential in the research of inflammation-related and cardiovascular .
    Sappanone A
  • HY-N2410

    N-feruloyltyramine; Moupinamide

    Reactive Oxygen Species (ROS) Apoptosis Inflammation/Immunology
    N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid, is a potent antioxidant. N-trans-Feruloyltyramine improves H2O2-induced intracellular ROS generation and decreases apoptosis. N-trans-Feruloyltyramine has the potential for oxidative stress-related neurodegenerative conditions and cancer research .
    N-trans-Feruloyltyramine
  • HY-30270

    p-Hydroxyanisole

    HSP Estrogen Receptor/ERR Endocrinology
    Mequinol (4-Methoxyphenol)yes MercurialisOne of the bioactive ingredients, mainly used for skin discoloration . MequinolIs an antioxidant that has additive/synergistic effects on carcinogenesis when combined with other phenolic antioxidants. Mequinolalso promote hERαDependent chaperone production with potential estrogenic activity .
    Mequinol
  • HY-B0373
    Tiopronin
    1 Publications Verification

    Others Metabolic Disease
    Tiopronin is a diffusible antioxidant, an antidote to heavy metal poisoning and a radioprotective agent. Tiopronin can control the rate of cystine precipitation and excretion and has the potential for cystinuria, rheumatoid arthritis and hepatic disorders .
    Tiopronin
  • HY-N2393
    Kukoamine B
    1 Publications Verification

    Apoptosis MMP MAPKAPK2 (MK2) p38 MAPK PI3K Akt Reactive Oxygen Species (ROS) DNA/RNA Synthesis Neurological Disease Metabolic Disease Inflammation/Immunology
    Kukoamine B, a spermine alkaloid, is a potent dual LPS and CpG DNA inhibitor with Kd values of 1.23 µM and 0.66 µM, respectively. Kukoamine B exerts anti-inflammatory, anti-diabetic, anti-oxidant, anti-osteoporotic and neuroprotective effects. Kukoamine B has the potential for the study of sepsis .
    Kukoamine B
  • HY-B0729
    Polaprezinc
    1 Publications Verification

    Zinc L-carnosine

    Biochemical Assay Reagents Inflammation/Immunology Cancer
    Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities.
    Polaprezinc
  • HY-W015229S

    Isotope-Labeled Compounds Endogenous Metabolite Reactive Oxygen Species (ROS) Neurological Disease Metabolic Disease
    3-Indolepropionic acid-d2 is the deuterium labeled 3-Indolepropionic acid. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease.
    3-Indolepropionic acid-d2
  • HY-121192
    Capillarisin
    1 Publications Verification

    Reactive Oxygen Species (ROS) Neurological Disease Inflammation/Immunology
    Capillarisin, as a constituent from Artemisiae Capillaris herba, is found to exert anti-inflammatory and antioxidant properties. Capillarisin can be used for the research of asthma-mediated complications and can be a potential neuroprotectant against bupivacaine-induced neurotoxicity .
    Capillarisin
  • HY-N2534
    Karanjin
    2 Publications Verification

    AMPK Apoptosis Cytochrome P450 Phosphatase NF-κB Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology Cancer
    Karanjin is an orally active furanoflavonoid which can be isolated from several Leguminosae. Karanjin exhibits evident anti-diabetic, anti-cancer, anti-inflammatory, antioxidant, anticolitis, anti-ulcer, anti-Alzheimer properties and multiple insect repellent/insecticidal, acaricide properties, suggesting the potential of Karanjin to be applied to relevant research .
    Karanjin
  • HY-W002620A

    2-Ethyl-3-hydroxy-6-methylpyridine succinate

    Reactive Oxygen Species (ROS) Infection Inflammation/Immunology
    Emoxypine succinate is an antioxidant. Emoxypine succinate can be used for the research of post-traumatic .
    Emoxypine succinate
  • HY-N2555
    Tilianin
    2 Publications Verification

    Others Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Tilianin is an active flavonoid glycoside found in many medical plants, with potential anti-hypertensive, myocardial-protective, anti-diabetic, anti-hyperlipidemic, anti-inflammatory and antioxidant effects .
    Tilianin
  • HY-N1082

    Others Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles .
    Visnagin
  • HY-N0106

    (Rac)-Danshensu sodium; (Rac)-Tanshinol sodium

    Keap1-Nrf2 NF-κB Mitochondrial Metabolism Apoptosis Infection Cardiovascular Disease Inflammation/Immunology
    (Rac)-Salvianic acid A sodium is the racemic form of Salvianic acid A (HY-N1913). Salvianic acid A is an orally active phenolic compound that induces Nrf2/HO-1 activation and inhibits the NF-κB pathway, and it also activates the mitochondrial antioxidant defense system (Mitochondrial Metabolism). Salvianic acid A exhibits anti-inflammatory, antioxidant, and anti-apoptotic properties (Apoptosis), demonstrating potential for research into inflammation and cardiovascular diseases .
    (Rac)-Salvianic acid A sodium
  • HY-Y0946

    Environmental Pollutants Inflammation/Immunology Cancer
    Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide derivatives may has antioxidant activity and potential anti-inflammatory activity. Acetamide holds promise for research in the fields of anti-inflammatory and cancer studies .
    Acetamide
  • HY-W047187

    Xanthine Oxidase NO Synthase TNF Receptor Others
    Lavandoside is an ABTS ?+ free radical scavenger and a moderate inhibitor of xanthine oxidase (XO), with an IC50 of 71.6 μM for inhibiting NO production in LPS-induced macrophages. Lavandoside exerts its antioxidant and potential anti-inflammatory effects by directly scavenging free radicals and inhibiting XO activity, a mechanism related to the hydroxyl groups in its molecular structure. Lavandoside can be isolated from lavender and can be used in the development of natural antioxidants and in research on oxidative stress-related diseases and inflammation-related diseases .
    Lavandoside
  • HY-W020182

    Terpilene

    Environmental Pollutants Fungal Parasite Infection
    α-Terpinene (Terpilene) is a monoterpene found in the essential oils of a large variety of foods and aromatic plants such as Mentha piperita. α-Terpinene is active against Trypanosoma evansi and has the potential for trypanosomosis treatment. α-Terpinene has antioxidant and antifungal properties .
    α-Terpinene
  • HY-N0411R

    Provitamin A (Standard); beta-Carotene (Standard)

    Reference Standards Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) Metabolic Disease Cancer
    β-Carotene (Standard) is the analytical standard of β-Carotene. This product is intended for research and analytical applications. β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .
    β-Carotene (Standard)
  • HY-108296

    Catalin K

    Reactive Oxygen Species (ROS) Metabolic Disease
    Pirenoxine (Catalin K) is a potent antioxidant. Pirenoxine shows anti-presbyopic activity. Pirenoxine has the potential for the research of cataracts .
    Pirenoxine
  • HY-N2565
    Rosamultin
    1 Publications Verification

    HIV Protease Apoptosis Infection
    Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina?L. Rosamultin has inhibitory effects against HIV-1 protease . Rosamultin has the potential for treating H2O2-induced oxidative stress injury through its antioxidant and antiapoptosis effects .
    Rosamultin
  • HY-N2188
    Beta-Acetoxyisovalerylshikonin
    1 Publications Verification

    HIV Infection
    Beta-Acetoxyisovalerylshikonin is a naturally occurring naphthoquinone-type shikonin derivative that is widely distributed in the roots and cell suspension cultures of *Arnebia euchroma*, *Arnebia guttata*, *Onosma hispidum* and *Lithospermum erythrorhizon*. Beta-Acetoxyisovalerylshikonin exhibits favorable antibacterial, anti-inflammatory, wound-healing promoting and antioxidant activities, and also possesses potential anti-tumor and anti-HIV properties .
    Beta-Acetoxyisovalerylshikonin
  • HY-W160560

    Reactive Oxygen Species (ROS) NF-κB Inflammation/Immunology Cancer
    4-Vinylsyringol is a phenolic compound with potential antioxidant and anti-inflammatory activities, which can be isolated from rapeseed oil .
    4-Vinylsyringol
  • HY-W015782

    Tyrosinase PKA Metabolic Disease Inflammation/Immunology
    4-Ethylresorcinol is a derivative of resorcinol and can serve as a substrate for tyrosinase. 4-Ethylresorcinol has anti-hyperpigmentation and antioxidant effects and can inhibit melanin synthesis. 4-Ethylresorcinol has potential whitening value .
    4-Ethylresorcinol
  • HY-W013494R

    Reference Standards Endogenous Metabolite Metabolic Disease Cancer
    L-Carnosine (Standard) is the analytical standard of L-Carnosine. This product is intended for research and analytical applications. L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging. In Vitro: L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging .
    L-Carnosine also exhibits some antioxidant effects. The antioxidant mechanism of L-Carnosine is attributed to its chelating effect against metal ions, superoxide dismutase (SOD)-like activity, and ROS and free radicals scavenging ability .
    L-Carnosine (Standard)
  • HY-113269
    alpha-CEHC
    1 Publications Verification

    Drug Metabolite Others
    alpha-CEHC is a water-soluble metabolite of alpha-tocopherol (α-TOH) with potential antioxidant activity. alpha-CEHC slightly inhibits macrophage-induced low-density lipoprotein (LDL) oxidation, and its inhibitory potency is concentration-dependent .
    alpha-CEHC
  • HY-N8167

    Kaempferol 3-O-rhamnosylgentiobioside

    COX Inflammation/Immunology
    Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research .
    Plantanone B
  • HY-117762
    U-83836E
    1 Publications Verification

    PNU-83836E

    Reactive Oxygen Species (ROS) Inflammation/Immunology
    U-83836E (PNU-83836E) is a compound with anti-inflammatory and antioxidant activities that reduces lung inflammation inhibiting oxidative stress and ROS production. U-83836E has shown potential for studying asthma and lung inflammation in animal models .
    U-83836E
  • HY-W236261

    ATEE

    Biochemical Assay Reagents Others
    N-Acetyl-L-tyrosine ethyl ester (ATEE) is a compound commonly used as a food flavoring and supplement. It is an ester of tyrosine, an amino acid found in many proteins. N-Acetyl-L-tyrosine ethyl ester is sweet, nutty and caramelized and is commonly used to enhance the flavor of baked goods, dairy products and beverages. Potential health benefits of N-Acetyl-L-tyrosine ethyl ester include its antioxidant properties and ability to improve cognitive function.
    N-Acetyl-L-tyrosine ethyl ester
  • HY-N2276

    Others Inflammation/Immunology
    Nodakenetin, isolated from Angelica decursiva, possesses antioxidant anti-inflammatory activities. Nodakenetin has the potential to be an antiarthritic and nerve tonic .
    Nodakenetin
  • HY-W015229R

    Indole-3-propionic acid (Standard); 3-IPA (Standard)

    Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS) Neurological Disease Metabolic Disease
    3-Indolepropionic acid (Standard) is the analytical standard of 3-Indolepropionic acid. This product is intended for research and analytical applications. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease. In Vitro: 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease . 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds . It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function .
    3-Indolepropionic acid (Standard)
  • HY-163830

    DAD9

    Dopamine Receptor Neurological Disease
    Pegasus (DAD9) is a potent dopamine receptor agonist. Pegasus shows antioxidant and anti-inflammatory properties. Pegasus inhibits α-Syn amyloid aggregation. Pegasus has the potential for the research of Parkinson’s disease .
    Pegasus
  • HY-W540232

    4-Methylphenyl ITC

    Cholinesterase (ChE) Neurological Disease
    4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is an antioxidant, with a IC50 value of 1.25 mM for scavenging DPPH radicals. ORAC testing indicates its antioxidant capacity as 11.7 mM TE (indicating that the antioxidant efficacy of this compound is equivalent to 11.7 mmol of Trolox (HY-101445, a standard antioxidant) under the same conditions), and it extends the oxidation process by approximately 9180 seconds in the Briggs–Rauscher reaction. Additionally, 4-Methoxyphenyl isothiocyanate exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% against acetylcholinesterase (AChE) and 17.9% against butyrylcholinesterase (BChE). 4-Methoxyphenyl isothiocyanate holds potential for research in the fields of antioxidation and neurological disorders .
    4-Methoxyphenyl isothiocyanate
  • HY-P1197
    Kisspeptin-10 (mouse, rat)
    2 Publications Verification

    Kisspeptin Receptor Cardiovascular Disease Inflammation/Immunology
    Kisspeptin-10 (mouse, rat) is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10 (mouse, rat) is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound .
    Kisspeptin-10 (mouse, rat)
  • HY-N7921

    Bacterial Others
    Urolithin M6 is a polyhydroxy-rich metabolite with potential antioxidant activity. Urolithin M6 is produced by intestinal microbial metabolism and may act as an analog of tannic acid compounds. The production of Urolithin M6 in humans requires specific bacterial 3-dehydroxylase activity, which provides a new mechanism for its biotransformation. The metabolic profile of Urolithin M6 helps to stratify volunteers and further explore its potential role in health and disease .
    Urolithin M6
  • HY-W127745

    Isovegetable alcohol

    Environmental Pollutants Biochemical Assay Reagents Others
    Isophytol is a diterpene alcohol commonly found in various plant species, especially in chloroplasts, where it plays a role in photosynthesis. Isophytols have unique chemical properties that make them important ingredients in a variety of industrial processes, including the production of perfumes, essences and cosmetics. It also has potential medicinal properties, including antioxidant and anti-inflammatory effects.
    Isophytol
  • HY-115051

    Others Others
    2-Hydroxymethyltetrahydropyran is a volatile compound in Sambucus williamsii (SW) seed oil. SW seed oil has potential antioxidant activity .
    2-Hydroxymethyltetrahydropyran
  • HY-B1351

    Cytochrome P450 Metabolic Disease
    Bilberry Extract is a bilberry extract, and its components include: Anthocyanidins. Bilberry Extract has potential antioxidant activity and can regulate specific metabolic enzymes in the liver, such as cytochrome P450 (CYP) 2C11 and CYP2E1 involved in drug metabolism. .
    Bilberry Extract
  • HY-P1197A
    Kisspeptin-10 (mouse, rat) TFA
    2 Publications Verification

    Kisspeptin Receptor Cardiovascular Disease Inflammation/Immunology
    Kisspeptin-10 (mouse, rat) TFA is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10 (mouse, rat) TFA is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 (mouse, rat) TFA reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound .
    Kisspeptin-10 (mouse, rat) TFA
  • HY-W010202

    3,7-Dimethyloct-6-en-3-ol

    Environmental Pollutants Others
    Dihydrolinalool, Dihydrolinalool is commonly used as a flavor ingredient in various products, including food, beverages, and perfumes, and it can also be used as a base material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. In addition, due to Dihydrolinalool's low toxicity and Biodegradability, which has been studied for its potential use as a bio-based solvent, has also been studied for its potential antioxidant and anti-inflammatory properties, which may make it useful in the study of various diseases, including cancer and Alzheimer's disease. Alzheimer's disease.
    Dihydrolinalool
  • HY-N16535

    Apoptosis Caspase Mitochondrial Metabolism Reactive Oxygen Species (ROS) Cancer
    Stigmalactam is an aristolactam-type alkaloid extracted from Orophea enterocarpa with anticancer effects. Stigmalactam induces apoptosis via the mitochondrial pathway, with the activation of caspase-3/9, and a decrease in mitochondrial membrane potential (MTP). Stigmalactam exhibits antioxidant activity by decreasing ROS production. Stigmalactam can be used for liver and breast cancer research .
    Stigmalactam
  • HY-N0411S4

    Provitamin A-13C10; beta-Carotene-13C10

    Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) Metabolic Disease Cancer
    β-Carotene- 13C10 (Provitamin A- 13C10) is the 13C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .
    β-Carotene-13C10
  • HY-145104

    Drug Derivative Others
    Antioxidant agent-1 is a new chalcone derivative as a potential antioxidant agent.
    Antioxidant agent-1
  • HY-N8837

    MMP Metabolic Disease
    Trifloroside is a secoiridoid glycoside with antioxidant effects. Trifloroside induces osteogenic effects through osteoblast differentiation, adhesion, migration, and mineral apposition. Trifloroside has the potential for osteoblast-mediated bone diseases research .
    Trifloroside
  • HY-N8598

    Others Cardiovascular Disease
    Caulophine is a fluoroketone alkaloid isolated from Caulophyllum robustum MAXIM. Caulophine has antioxidant activity and the ability to protect cardiomyocytes from oxidative and ischemic damage, providing potential value for coronary heart disease research .
    Caulophine
  • HY-N16639

    Drug Derivative Inflammation/Immunology
    (+)-Catechin-3’-O-β-D-glucoside is a mono glucoside derivative of (+)-catechin (HY-N0898) after biotransformation. (+)-Catechin-3’-O-β-D-glucoside is a potential antioxidant .
    (+)-Catechin-3′-O-β-D-glucoside
  • HY-149207

    Tyrosinase Metabolic Disease
    Tyrosinase-IN-11 is a potent tyrosinase inhibitor with IC50s of 50 nM and 64 nM for L-tyrosinase and L-dopa, respectively. Tyrosinase-IN-11 has significant antioxidant activity and low cytotoxicity. Tyrosinase-IN-11 has the potential for skin hyperpigmentation research .
    Tyrosinase-IN-11
  • HY-N12726

    p38 MAPK MMP Infection Inflammation/Immunology Cancer
    Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum. Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities .
    Halociline
  • HY-N5057

    Others Cardiovascular Disease
    Przewalskinic acid A is a phenolic acid found in the Salvia przewalskii Maxim herb. Phenolic acids show potent antioxidant activities and potential effects in protecting against brain and heart damage caused by ischemia reperfusion .
    Przewalskinic acid A

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