Plantanone B
Based on 1 Customer Validation
Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research.
For research use only. We do not sell to patients.
- Purity: 99.16%
- CAS No.: 55780-30-8
- Formula: C33H40O20
- Molecular Weight:756.66
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Ovine COX-1 21.78±0.2 μM (IC50) |
Ovine COX-2 44.01±0.42 μM (IC50) |
The antioxidant activity of Plantanone B is measured by the DPPH method. Plantanone B exhibits a moderate antioxidant activity, with an IC50 value of 169.8±5.2 μM[1].Plantanone B?inhibits COX-1 preferentially over COX-2 with selectivity index (SI) value of 0.49. It shows significant inhibitory activities against ovine COX-1 and COX-2 at concentration of 50 μM, with the inhibition of 76.18% and 21.78%, respectively[1]..Plantanone B?shows significant COX-1 and moderate COX-2 inhibitory activities with IC50?values of 21.78±0.20 μM for COX-1, as well as 44.01±0.42 μM for COX-2, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 55780-30-8
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Appearance Solid
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Molecular Weight 756.66
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Formula C33H40O20
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Color Off-white to light yellow
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SMILES
O=C1C(O[C@H](O[C@@H]2CO[C@@H]([C@@H]([C@H]3O)O)O[C@@H]([C@H]3O)CO)[C@@H]([C@H]([C@@H]2O)O)O[C@H](O[C@H]4C)[C@@H]([C@@H]([C@H]4O)O)O)=C(C(C=C5)=CC=C5O)OC6=CC(O)=CC(O)=C16
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Synonyms
Kaempferol 3-O-rhamnosylgentiobioside
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 7.6 mg/mL (10.04 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3216 mL | 6.6080 mL | 13.2160 mL | 33.0399 mL |
| 5 mM | 0.2643 mL | 1.3216 mL | 2.6432 mL | 6.6080 mL | |
| 10 mM | 0.1322 mL | 0.6608 mL | 1.3216 mL | 3.3040 mL |
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