1. Immunology/Inflammation
  2. COX
  3. Plantanone B

Plantanone B (Synonyms: Kaempferol 3-O-rhamnosylgentiobioside)

Cat. No.: HY-N8167
Handling Instructions

Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research.

For research use only. We do not sell to patients.

Plantanone B Chemical Structure

Plantanone B Chemical Structure

CAS No. : 55780-30-8

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Description

Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research[1].

IC50 & Target[1]

Ovine COX-1

21.78±0.2 μM (IC50)

Ovine COX-2

44.01±0.42 μM (IC50)

In Vitro

The antioxidant activity of Plantanone B is measured by the DPPH method. Plantanone B exhibits a moderate antioxidant activity, with an IC50 value of 169.8±5.2 μM[1].
Plantanone B inhibits COX-1 preferentially over COX-2 with selectivity index (SI) value of 0.49. It shows significant inhibitory activities against ovine COX-1 and COX-2 at concentration of 50 μM, with the inhibition of 76.18% and 21.78%, respectively[1].
.Plantanone B shows significant COX-1 and moderate COX-2 inhibitory activities with IC50 values of 21.78±0.20 μM for COX-1, as well as 44.01±0.42 μM for COX-2, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

756.66

Formula

C₃₃H₄₀O₂₀

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Plantanone B
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HY-N8167
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