AChE-IN-111
AChE-IN-111 is an acetylcholinesterase inhibitor with a IC50 of 0.37 μM. AChE-IN-111 scavenges various reactive oxygen and nitrogen species. AChE-IN-111 exhibits significant antioxidant potential and iron regulatory protein levels. AChE-IN-111 can be used for the research of Alzheimer's disease.
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- Formule: C26H26N4O7S
- Masse moléculaire:538.57
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
In Vitro
AChE-IN-111 (Compound 4q) (62.5 μg/mL) exhibits weak inhibitory activity against butyrylcholinesterase, with an inhibition rate of 33.6%[1].
AChE-IN-111 (10 μg/mL) exhibits potent in vitro antioxidant potential, with a total antioxidant capacity of 83.05 mg gallic acid/g and an IRP level of 123.4 μM[1].
AChE-IN-111 (10 μg/mL) exhibits in vitro antioxidant and free radical scavenging activities against DPPH, ABTS, NO, OH and H2O2 free radicals, with IC50 values of 11.38, 9.88, 14.45, 18.68 and 21.15 μM, respectively[1].
AChE-IN-111 exhibits CYP450 inhibitory activity, with inhibitory effects on CYP2C19, CYP2C9, and CYP3A4[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 538.57
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Formule C26H26N4O7S
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SMILES
CCS(=O)(OC1=CC(/C=N/NC(COC2=CC=C(C3=NC4=CC=CC=C4N3)C=C2OC)=O)=CC=C1OC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE-IN-111 Related Classifications
HY-182332 Related Classifications
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