2. Apoptosis
  3. Apoptosis Caspase
  4. Ganoderic acid T1

Ganoderic acid T1 is a deacetylated derivative of Ganoderic acid T. Ganoderic acid T1 attenuates antioxidant defense system and induces apoptosis of cancer cells. Ganoderic acid T1 decreases mitochondrial membrane potential and activates caspase-9 and caspase-3, to trigger apoptosis. Ganoderic acid T1 also increases the generation of intracellular ROS to produce pro-oxidant activities and cytotoxicity.

For research use only. We do not sell to patients.

Ganoderic acid T1 Chemical Structure

Ganoderic acid T1 Chemical Structure

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Ganoderic acid T1 Related Antibodies

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Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase Caspase 11 Caspase-13

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Description

Ganoderic acid T1 is a deacetylated derivative of Ganoderic acid T. Ganoderic acid T1 attenuates antioxidant defense system and induces apoptosis of cancer cells. Ganoderic acid T1 decreases mitochondrial membrane potential and activates caspase-9 and caspase-3, to trigger apoptosis. Ganoderic acid T1 also increases the generation of intracellular ROS to produce pro-oxidant activities and cytotoxicity[1].

IC50 & Target[1]

Caspase 3

 

Caspase-9

 

Molecular Weight

570.76

Formula

C34H50O7
SMILES

C[C@]12C3=CCC4C([C@H](OC(C)=O)CC[C@@]4(C3=CC[C@]1(C)C([C@@H]([C@H](C/C=C(C(O)=O)\C)O)C)C[C@@H]2OC(C)=O)C)(C)C
Structure Classification
Initial Source

Ganoderma lucidum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ganoderic acid T1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ganoderic acid T1Ganoderic acid T 1Ganoderic acid T-1ApoptosisCaspaseInhibitorinhibitorinhibit

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