BChE-IN-33
BChE-IN-33 (compound 4r), an arylaminonaphthol derivative, is a potent butyrylcholinesterase (BChE) inhibitor with an IC50 of 14.78 µM. BChE-IN-33 also inhibits CYP2C19, CYP2C9, CYP2D6. BChE-IN-33 shows potent antioxidant activity with IC50 values of 150.48 μM, 2.56 μM and 4.61 μM by DPPH, ABTS, Ferric-phenanthroline assay, respectively. BChE-IN-33 has the potential for Alzheimer research.
For research use only. We do not sell to patients.
- Formula: C23H17ClN2O3
- Molecular Weight:404.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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BChE 14.78 nM (IC50) |
CYP2C19 |
CYP2C9 |
CYP2D6 |
Chemical Information
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Molecular Weight 404.85
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Formula C23H17ClN2O3
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SMILES
OC1=CC=C2C=CC=CC2=C1C(NC3=CC=C(Cl)C=C3)C4=CC=CC([N+]([O-])=O)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)