BuChE-IN-TM-10
BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer’s disease.
For research use only. We do not sell to patients.
- CAS No.: 2313524-95-5
- Formula: C32H38N2O3
- Molecular Weight:498.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 8.9 nM (BuChE)[1].
Chemical Information
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CAS No. 2313524-95-5
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Molecular Weight 498.66
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Formula C32H38N2O3
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SMILES
O=C(N1CC2=C(C=CC=C2)CC1)/C=C/C3=CC=C(OCCCCN(CC4=CC=CC=C4)CC)C(OC)=C3
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Synonyms
TM-10
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)