1. Neuronal Signaling
  2. AChE
  3. BuChE-IN-TM-10

BuChE-IN-TM-10 (Synonyms: TM-10)

Cat. No.: HY-114320
Handling Instructions

BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer’s disease.

For research use only. We do not sell to patients.

BuChE-IN-TM-10 Chemical Structure

BuChE-IN-TM-10 Chemical Structure

CAS No. : 2313524-95-5

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Description

BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer’s disease[1].

IC50 & Target

IC50: 8.9 nM (BuChE)[1].

Molecular Weight

498.66

Formula

C₃₂H₃₈N₂O₃

CAS No.

2313524-95-5

SMILES

O=C(N1CC2=C(C=CC=C2)CC1)/C=C/C3=CC=C(OCCCCN(CC4=CC=CC=C4)CC)C(OC)=C3

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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