2313524-95-5
Chemical Structure
BuChE-IN-TM-10
Synonym(s): TM-10
- CAS No.: 2313524-95-5
- Formula:C32H38N2O3
- Molecular Weight:498.66
IUPAC Name: (E)-3-(4-(4-(benzyl(ethyl)amino)butoxy)-3-methoxyphenyl)-1-(3,4-dihydroisoquinolin-2(1H)-yl)prop-2-en-1-one
InChIKey: CGZGXSZYVAXOGJ-FBMGVBCBSA-N
SMILES: O=C(N1CC2=C(C=CC=C2)CC1)/C=C/C3=CC=C(OCCCCN(CC4=CC=CC=C4)CC)C(OC)=C3
Biological Activity: BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer’s disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BuChE-IN-TM-10 | BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer’s disease. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
