(Rac)-Salvianic acid A sodium (Standard)
(Rac)-Salvianic acid A (sodium) (Standard) is the analytical standard of (Rac)-Salvianic acid A (sodium). This product is intended for research and analytical applications. (Rac)-Salvianic acid A sodium is the racemic form of Salvianic acid A (HY-N1913). Salvianic acid A is an orally active phenolic compound that induces Nrf2/HO-1 activation and inhibits the NF-κB pathway, and it also activates the mitochondrial antioxidant defense system (Mitochondrial Metabolism). Salvianic acid A exhibits anti-inflammatory, antioxidant, and anti-apoptotic properties (Apoptosis), demonstrating potential for research into inflammation and cardiovascular diseases.
For research use only. We do not sell to patients.
- Purity: 95%
- CAS No.: 67920-52-9
- Formula: C9H9NaO5
- Molecular Weight:220.15
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 67920-52-9
-
Molecular Weight 220.15
-
Formula C9H9NaO5
-
SMILES
OC1=C(O)C=CC(CC(C(O[Na])=O)O)=C1
-
Synonyms
(Rac)-Danshensu sodium (Standard); (Rac)-Tanshinol sodium (Standard)
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wei Wang, et al. Danshensu alleviates pseudo-typed SARS-CoV-2 induced mouse acute lung inflammation. Acta Pharmacol Sin. 2022 Apr;43(4):771-780. [Content Brief]
[2]. V Bharath Kumar, et al. Sodium Danshensu Inhibits Oral Cancer Cell Migration and Invasion by Modulating p38 Signaling Pathway. Front Endocrinol (Lausanne). 2020 Sep 30:11:568436. [Content Brief]
[3]. Chen Yu, et al. Danshensu attenuates cisplatin-induced nephrotoxicity through activation of Nrf2 pathway and inhibition of NF-κB. Biomed Pharmacother. 2021 Oct:142:111995. [Content Brief]
[4]. Wu Y, et al. The Effect of Salvianolic Acid on Vascular Protection and Possible Mechanisms. Oxid Med Cell Longev. 2020 Sep 25;2020:5472096. doi: 10.1155/2020/5472096. [Content Brief]
[5]. Zhao QT, et al. Salvianic acid A inhibits lipopolysaccharide-induced apoptosis through regulating glutathione peroxidase activity and malondialdehyde level in vascular endothelial cells. Chin J Nat Med. 2012 Jan;10(1):53-7. [Content Brief]
[6]. Jia D, et al. Salvianic acid A sodium protects HUVEC cells against tert-butyl hydroperoxide induced oxidative injury via mitochondria-dependent pathway. Chem Biol Interact. 2018 Jan 5;279:234-242. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- (Rac)-Salvianic acid A sodium (Standard)
- 67920-52-9
- (Rac)-Danshensu sodium (Standard)
- (Rac)-Tanshinol sodium (Standard)
- Reference Standards
- Keap1-Nrf2
- NF-κB
- Mitochondrial Metabolism
- Apoptosis
- Orally
- HO-1
- antioxidant defense mechanism
- anti-oxidation
- anti-apoptosis
- lung inflammatory
- COVID-19
- cardiovascular
- cerebrovascular
- Inhibitor
- inhibitor
- inhibit