1. Immunology/Inflammation
    Cytoskeleton
    Metabolic Enzyme/Protease
  2. Toll-like Receptor (TLR)
    MyD88
    Dynamin
    Mitochondrial Metabolism
  3. Schaftoside

Schaftoside 

Cat. No.: HY-N0703
Handling Instructions

Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission.

For research use only. We do not sell to patients.

Schaftoside Chemical Structure

Schaftoside Chemical Structure

CAS No. : 51938-32-0

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Description

Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission[1].

In Vitro

Schaftoside inhibits three pro-inflammatory enzymatic activities: secretory phospholipase A2 (sPLA2), lipoxygenase (LOX), and cyclooxygenase 2 (COX-2). Schaftoside also inhibits mRNA and protein expressions of proinflammatory cytokines(IL-1β, TNF-α, and IL-6)[1].

Molecular Weight

564.49

Formula

C₂₆H₂₈O₁₄

CAS No.

51938-32-0

SMILES
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Please store the product under the recommended conditions in the Certificate of Analysis.

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Schaftoside
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HY-N0703
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