AChE/BChE/MAO-B-IN-4
AChE/BChE/MAO-B-IN-4, an indan-1-one derivative, is a potent MAO-B inhibitor with an IC50 of 0.0393 μM for human MAO-B. AChE/BChE/MAO-B-IN-4 is a potent AChE and BChE enzyme inhibitor, with IC50s of 0.0458 μM and 0.075 μM for human AChE and BChE enzyme, respectively. AChE/BChE/MAO-B-IN-4 shows significant antioxidant activity and prevent β-amyloid plaque aggregation. AChE/BChE/MAO-B-IN-4 has the potential for Alzheimer's disease (AD) research.
For research use only. We do not sell to patients.
- Formula: C26H33N3O4
- Molecular Weight:451.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
AChE/BChE/MAO-B-IN-4 (compound D39) has the IC50 value of 12.3498 μM on the NIH/3T3 fibroblast cell line[1].
AChE/BChE/MAO-B-IN-4 (1 mM) demonstrates strong human AChE and BChE enzyme inhibition profiles by generating at 92% activity, respectively[1].
AChE/BChE/MAO-B-IN-4 has an IC50 value of 0.1966 μM on β-amyloid plaque aggregation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 451.56
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Formula C26H33N3O4
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SMILES
O=C(NC1=CC=C(/C=C(CC2=C3C=C(OC)C(OC)=C2)\C3=O)C=C1)CN(C)CCCN(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE/BChE/MAO-B-IN-4 Related Classifications
HY-152114 Related Classifications
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