AChE/BChE/MAO-B-IN-3
AChE/BChE/MAO-B-IN-3, an indan-1-one derivative, is a potent MAO-B inhibitor with an IC50 of 0.0359 μM for human MAO-B. AChE/BChE/MAO-B-IN-3 is a potent AChE and BChE enzyme inhibitor, with IC50s of 0.0473 μM and 0.0782 μM for human AChE and BChE enzyme, respectively. AChE/BChE/MAO-B-IN-3 shows significant antioxidant activity and has the potential for Alzheimer's disease (AD) research.
For research use only. We do not sell to patients.
- Formula: C25H31N3O3
- Molecular Weight:421.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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hMAO-B 0.0359 μM (IC50) |
hAChE 0.0473 μM (IC50) |
hBCHE 0.0782 μM (IC50) |
AChE/BChE/MAO-B-IN-3 (compound D38) has the IC50 value of 6.8118 μM on the NIH/3T3 fibroblast cell line[1].
AChE/BChE/MAO-B-IN-3 (1 mM) demonstrates strong human AChE and BChE enzyme inhibition profiles by generating at 93% activity, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 421.53
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Formula C25H31N3O3
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SMILES
O=C(NC1=CC=C(/C=C(CC2=C3C=C(OC)C=C2)/C3=O)C=C1)CN(C)CCCN(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE/BChE/MAO-B-IN-3 Related Classifications
HY-152113 Related Classifications
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