COX-2/LOX-IN-2
COX-2/LOX-IN-2 (compound 6) is a dual inhibitor of COX-2/LOX with IC50s of 7.0 μM and 27.5 μM, respectively. COX-2/LOX-IN-2 has antioxidant activity and has the potential to be used in the development of nonsteroidal anti-inflammatory drugs (tNSAIDs).
For research use only. We do not sell to patients.
- Formula: C28H23ClN2O2
- Molecular Weight:454.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
7.0 μM (COX-2), 27.5 μM (Lipoxygenase, LOX)[1]
Chemical Information
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Molecular Weight 454.95
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Formula C28H23ClN2O2
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SMILES
CN(C)C1=CC=C(C2=CN(C=C2C(C3=CC=C(Cl)C=C3)=O)C(/C=C/C4=CC=CC=C4)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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