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Results for "

interleukin-1

" in MedChemExpress (MCE) Product Catalog:

47

Inhibitors & Agonists

1

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7

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3

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5

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118

Recombinant Proteins

1

Isotope-Labeled Compounds

12

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Cat. No. Compare Product Name Species Source
  • HY-P700212AF
    Animal-Free IL-36RN Protein, Mouse (His)

    IL-36RA; IL-36RA; interleukin-36 Receptor Antagonist Protein; IL-1RP3; interleukin-1; interleukin-1 FamILy Member 5; IL-1F5; interleukin-1-Like Protein 1; IL-1L1; IL36RN; FIL1D; IL1F5; IL1HY1; IL1RP3

    		 Mouse E. coli
    IL-36RN Protein inhibits IL36A, IL36B and IL36G receptors by binding to IL1RL2/IL-36R, blocking their association with IL1RAP and inhibiting downstream signaling. It is an important component of the IL-36 signaling system and participates in the local inflammatory response of the epithelial barrier. Animal-Free IL-36RN Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-36RN protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-36RN Protein, Mouse (His) is 155 a.a., with molecular weight of ~17.81 kDa.
  • HY-P700127AF
    Animal-Free IL-36RN Protein, Human (His)

    IL-36RA; IL-36Ra; interleukin-36 Receptor Antagonist Protein; IL-1RP3; interleukin-1; interleukin-1 Family Member 5; IL-1F5; interleukin-1-Like Protein 1; IL-1L1; IL36RN; FIL1D; IL1F5; IL1HY1; IL1RP3

    		 Human E. coli
    IL-36RN protein tightly regulates immunity by inhibiting the activity of interleukin 36 (IL36A, IL36B, IL36G). It binds to the IL-36 receptor (IL1RL2), preventing binding to IL1RAP and blocking downstream signaling. Animal-Free IL-36RN Protein, Human (His) is the recombinant human-derived animal-FreeIL-36RN protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-36RN Protein, Human (His) is 108 a.a., with molecular weight of ~17.77 kDa.
  • HY-P71965
    IL-36RN Protein, Human

    IL-36RA; IL-36Ra; interleukin-36 Receptor Antagonist Protein; IL-1RP3; interleukin-1; interleukin-1 Family Member 5; IL-1F5; interleukin-1-Like Protein 1; IL-1L1; IL36RN; FIL1D; IL1F5; IL1HY1; IL1RP3

    		 Human E. coli
    IL-36RN Protein, Human, a member of the interleukin 1 cytokine family, is a IL-36 receptor antagonist.
  • HY-P79243
    IL-1 alpha/IL-1F1 Protein, Porcine

    interleukin-1 alpha; IL1A; IL-1 alpha; interleukin 1 alpha

    		 Porcine E. coli
    The IL-1α/IL-1F1 protein is found intracellularly in most non-hematopoietic cells and plays a crucial role in mediating inflammation and linking innate and adaptive immunity. IL1RAP binds to IL1R1 to form a high-affinity receptor complex that activates cascades and pathways. IL-1 alpha/IL-1F1 Protein, Porcine is the recombinant Porcine-derived IL-1 alpha/IL-1F1 protein, expressed by E. coli , with tag free. The total length of IL-1 alpha/IL-1F1 Protein, Porcine is 152 a.a., with molecular weight of ~17.5 kDa.
  • HY-P700242AF
    Animal-Free IL-1 alpha/IL-1F1 Protein, Pig (His)

    interleukin-1 alpha; IL1A; IL-1 alpha; interleukin 1 alpha

    		 Pig E. coli
    The IL-1α/IL-1F1 protein is found intracellularly in most non-hematopoietic cells and plays a crucial role in mediating inflammation and linking innate and adaptive immunity. IL1RAP binds to IL1R1 to form a high-affinity receptor complex that activates cascades and pathways. Animal-Free IL-1 alpha/IL-1F1 Protein, Pig (His) is the recombinant pig-derived animal-FreeIL-1 alpha/IL-1F1 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-1 alpha/IL-1F1 Protein, Pig (His) is 158 a.a., with molecular weight of ~19.02 kDa.
  • HY-P702336
    IL1R1 Protein, Human (Cell-Free, His, SUMO, Myc)

    interleukin-1 receptor type 1; CD121 antigen-like family member A; interleukin-1 receptor alpha; IL-1R-alpha; interleukin-1 receptor type I; p80

    		 Human E. coli Cell-free
    IL1R1 protein is the receptor for IL1A, IL1B and IL1RN and forms a high-affinity complex with IL1RAP upon ligand binding. This complex activates NF-kappa-B, MAPK and other pathways, recruiting adapter molecules such as TOLLIP, MYD88 and IRAK1 or IRAK2. IL1R1 Protein, Human (Cell-Free, His, SUMO, Myc) is the recombinant human-derived IL1R1 protein, expressed by E. coli Cell-free , with N-10*His, C-Myc, N-SUMO labeled tag. The total length of IL1R1 Protein, Human (Cell-Free, His, SUMO, Myc) is 552 a.a., with molecular weight of 83.5 kDa.
  • HY-P79293
    IL-1RA/IL-1F3 Protein, Porcine

    interleukin-1 receptor antagonist protein; IL1RN; IL-1RN; IL-1ra; IRAP; IL1 inhibitor; IRAP1; interleukin 1 Receptor Antagonist

    		 Porcine E. coli
    The IL-1RA/IL-1F3 protein, a robust anti-inflammatory antagonist in the interleukin-1 family, specifically targets proinflammatory cytokines IL1B and IL1A. Countering IL1's inflammatory effects, this protein crucially protects against immune dysregulation and prevents uncontrolled systemic inflammation triggered by various innate stimulatory agents, including pathogens. Serving as a regulatory shield against IL1-mediated responses, IL-1RA/IL-1F3 significantly contributes to maintaining immune balance and curtailing excessive inflammatory reactions. IL-1RA/IL-1F3 Protein, Porcine is the recombinant Porcine-derived IL-1RA/IL-1F3 protein, expressed by E. coli, with tag free. The total length of IL-1RA/IL-1F3 Protein, Porcine is 152 a.a., with molecular weight of ~17.55 kDa.
  • HY-P72117
    Caspase-1/CASP1 Protein, Human (GST)

    CASP-1; CASP1; CASP1_HUMAN; Caspase 1; ICE; IL-1 beta-converting enzyme; IL-1BC; IL1 beta converting enzyme; IL1B convertase; interleukin 1 beta convertase; interleukin 1B converting enzyme; interleukin-1 beta convertase; interleukin-1 beta-converting enzyme; p45

    		 Human E. coli
    Caspase-1/CASP1 is a thiol protease complex involved in inflammation by catalyzing the cleavage of IL1B, IL18, and Gasdermin-D (GSDMD). It activates a pro-inflammatory response, releases mature cytokines IL1B and IL18, and initiates pyroptosis through cleavage of GSDMD. Caspase-1/CASP1 Protein, Human (GST) is the recombinant human-derived Caspase-1/CASP1 protein, expressed by E. coli , with N-GST labeled tag. The total length of Caspase-1/CASP1 Protein, Human (GST) is 150 a.a., with molecular weight of ~43.8 kDa.
  • HY-P70437
    IL-1beta Protein, Mouse

    interleukin-1 Beta; IL-1 Beta; Il1b

    		 Mouse E. coli
    IL-1 beta protein is a potent pro-inflammatory cytokine and major endogenous pyrogen that induces immune cell effects such as prostaglandin synthesis, neutrophil activation, T- and B-cell activation, and fibroblast proliferation . It promotes Th17 differentiation and synergizes with IL12 to promote Th1 IFNG synthesis. IL-1beta Protein, Mouse is the recombinant mouse-derived IL-1beta protein, expressed by E. coli , with tag free. The total length of IL-1beta Protein, Mouse is 152 a.a., with molecular weight of ~16.0 kDa.
  • HY-P72572
    IL-1 alpha Protein, Rat

    interleukin-1 alpha; IL-1 alpha; Il1a

    		 Rat E. coli
    IL-1 alpha is a ubiquitous and pivotal pro-inflammatory cytokine. IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha plays an important role in inflammation and bridges the innate and adaptive immune systems. IL-1 alpha mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways. IL-1 alpha protein, Rat is a recombinant protein consisting of 156 amino acids (S115-S270) and is produced by E. coli.
  • HY-P72571
    IL-1 beta Protein, Cavia porcellus (His)

    interleukin-1 beta; IL-1 beta; IL1B

    		 Others E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions.  IL-1 beta Protein, Cavia porcellus (His) is produced in  E. coli with six C-Terminal His-tags. It consists of 152 amino acids (T115-S266).
  • HY-P77411
    IL-1RAcP/IL-1 R3 Protein, Cynomolgus (HEK293, Fc)

    interleukin-1 Receptor Accessory Protein; IL-1RAcP; interleukin-1 Receptor 3; IL-1R3; IL1RAP; C3orf13

    		 Cynomolgus HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Cynomolgus (HEK293, Fc) is a recombinant cynomolgus IL-1RAcP protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 359 amino acids (M1-E359).
  • HY-P77412
    IL-1RAcP/IL-1 R3 Protein, Cynomolgus (HEK293, His)

    interleukin-1 Receptor Accessory Protein; IL-1RAcP; interleukin-1 Receptor 3; IL-1R3; IL1RAP; C3orf13

    		 Cynomolgus HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Cynomolgus (HEK293, His) is a recombinant cynomolgus IL-1RAcP protein with a His tag at the C-terminus and is expressed in HEK293 cells. It consists of 359 amino acids (M1-E359).
  • HY-P77413
    IL-1RAcP/IL-1 R3 Protein, Human (HEK293, Fc)

    interleukin-1 Receptor Accessory Protein; IL-1RAcP; interleukin-1 Receptor 3; IL-1R3; IL1RAP; C3orf13

    		 Human HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Human (HEK293, Fc) is a recombinant human IL-1RAcP protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 359 amino acids (M1-E359).
  • HY-P77417
    IL-1RAcP/IL-1 R3 Protein, Mouse (HEK293, Fc)

    interleukin-1 Receptor Accessory Protein; IL-1RAcP; interleukin-1 Receptor 3; IL-1R3; IL1RAP; C3orf13

    		 Mouse HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Mouse (HEK293, Fc) is a recombinant mouse IL-1RAcP protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 350 amino acids (M1-K350).
  • HY-P70586
    IL-1 beta Protein, Human (solution)

    interleukin-1 beta; Catabolin; IL1F2; IL1B.

    		 Human E. coli
    IL-1 beta protein is a potent proinflammatory cytokine that plays multiple roles in immune responses. It induces inflammatory events including prostaglandin synthesis, neutrophil activation, and cytokine production. IL-1 beta Protein, Human (solution) is the recombinant human-derived IL-1 beta protein, expressed by E. coli , with tag free. The total length of IL-1 beta Protein, Human (solution) is 153 a.a., with molecular weight of ~16.61 kDa.
  • HY-P71866
    IL-1 alpha Protein, Rhesus macaque

    IL1A; interleukin-1 alpha; IL-1 alpha; Hematopoietin-1

    		 Rhesus Macaque E. coli
    IL-1 alpha, a cytokine present in non-hematopoietic cells, links innate and adaptive immunity. Binding to its receptor IL1R1, IL-1 alpha forms a receptor complex, activating signaling pathways involving MYD88, IRAK1, and IRAK4. It activates NF-kappa-B and MAPK pathways. Released during cell death, IL-1 alpha induces inflammation, senses DNA damage, and interacts with TMED10, IL1R1, and S100A13 for secretion and plasma membrane translocation. IL-1 alpha Protein, Rhesus macaque is the recombinant Rhesus Macaque-derived IL-1 alpha protein, expressed by E. coli , with tag free. The total length of IL-1 alpha Protein, Rhesus macaque is 159 a.a., with molecular weight of ~18.1 kDa.
  • HY-P70586G
    GMP IL-1 beta Protein, Human

    interleukin-1 beta; Catabolin; IL1F2; IL1B

    		 Human E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions.  GMP IL-1 beta Protein, Human, is a recombinant GMP-grade protein, consists of 153 amino acids (A117-S269) and is expressed in E. coli.
  • HY-P700210AF
    Animal-Free IL-36 alpha/IL-1F6 Protein, Mouse (His)

    Il36a; Fil1e; Il1e; Il1f6; Il1h1interleukin-36 alpha; FIL1 epsilon; interleukin-1 epsilon; IL-1 epsilon; interleukin-1 family member 6; IL-1F6; interleukin-1 homolog 1; IL-1H1

    		 Mouse E. coli
    IL-36 alpha protein binds to the IL1RL2/IL-36R receptor and activates the NF-kappa-B and MAPK signaling pathways. Animal-Free IL-36 alpha/IL-1F6 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-36 alpha/IL-1F6 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-36 alpha/IL-1F6 Protein, Mouse (His) is 160 a.a., with molecular weight of ~18.82 kDa.
  • HY-P70455
    IL-37 Protein, Human
    1 Publications Verification

    interleukin-37; FIL1 Zeta; IL-1X; interleukin-1 Family Member 7; IL-1F7; interleukin-1 Homolog 4; IL-1H; IL-1H4; interleukin-1 Zeta; IL-1 Zeta; interleukin-1-Related Protein; IL-1RP1; interleukin-23; IL-37; IL37; FIL1Z; IL1F7; IL1H4; IL1RP1

    		 Human E. coli
    IL-37 protein is an important immunoregulatory cytokine that suppresses innate inflammation and immune responses and reduces excessive inflammation. It signals intracellularly through nuclear translocation of SMAD3 and extracellularly through binding to its receptors, consisting of IL18R1 and IL18RAP. IL-37 Protein, Human is the recombinant human-derived IL-37 protein, expressed by E. coli , with tag free. The total length of IL-37 Protein, Human is 166 a.a., with molecular weight of ~18-20 kDa.
  • HY-P700213AF
    Animal-Free IL-1F10/IL-38 Protein, Mouse (His)

    interleukin 1 family; member 10; IL1F10

    		 Mouse E. coli
    IL-1F10/IL-38 proteins regulate immune responses. Animal-Free IL-1F10/IL-38 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-1F10/IL-38 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-1F10/IL-38 Protein, Mouse (His) is 152 a.a., with molecular weight of ~17.89 kDa.
  • HY-P72565
    IL-1RAcP/IL-1 R3 Protein, Human (339a.a, HEK293, His)

    interleukin-1 Receptor Accessory Protein; IL-1RAcP; interleukin-1 Receptor 3; IL-1R3; IL1RAP; C3orf13

    		 Human HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Human (339a.a, HEK293, His) is a recombinant human IL-1RAcP protein with a His tag at the C-terminus and is expressed in HEK293 cells. It consists of 339 amino acids (S21-E359).
  • HY-P77418
    IL-1RAcP/IL-1 R3 Protein, Mouse (350a.a, HEK293, His)

    interleukin-1 Receptor Accessory Protein; IL-1RAcP; interleukin-1 Receptor 3; IL-1R3; IL1RAP; C3orf13

    		 Mouse HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Mouse (350a.a, HEK293, His) is a recombinant mouse IL-1RAcP protein with a His tag at the C-terminus and is expressed in HEK293 cells. It consists of 350 amino acids (M1-K350).
  • HY-P700128AF
    Animal-Free IL-37 Protein, Human (His)

    interleukin-37; FIL1 Zeta; IL-1X; interleukin-1 Family Member 7; IL-1F7; interleukin-1 Homolog 4; IL-1H; IL-1H4; interleukin-1 Zeta; IL-1 Zeta; interleukin-1-Related Protein; IL-1RP1; interleukin-23; IL-37; IL37; FIL1Z; IL1F7; IL1H4; IL1RP1

    		 Human E. coli
    IL-37 protein is an important immunoregulatory cytokine that suppresses innate inflammation and immune responses and reduces excessive inflammation. It signals intracellularly through nuclear translocation of SMAD3 and extracellularly through binding to its receptors, consisting of IL18R1 and IL18RAP. Animal-Free IL-37 Protein, Human (His) is the recombinant human-derived animal-FreeIL-37 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-37 Protein, Human (His) is 166 a.a., with molecular weight of ~19.49 kDa.
  • HY-P72569
    IL-1R1 Protein, Human (315a.a, HEK293, His)

    interleukin-1 receptor type 1; IL-1R-1; IL-1RT-1; interleukin-1 receptor alpha; IL-1R-alpha; p80; CD121a    

    		 Human HEK293
    IL-1R1 (CD121a) belongs to IL-1 receptor, and binds to IL-1α, IL-1β, IL-1Ra and IL-38 with comparable affinities (Kd: 0.1-1 nM). IL-1R1 regulates the transcription of multiple proinflammatory cytokines and mediates immune and inflammatory responses, including the activation of NF-κB and MAPK pathway. IL-1R1 Protein, Human (315a.a, HEK293, His) is a recombinant human extracellular region of IL-1R1 (L18-T332) with a C-Terminal 6*His tag, which is produced in HEK293 cells.
  • HY-P701789
    IRAK1 Protein, Human (Sf9, GST)

    IRAK1; interleukin-1 receptor-associated kinase 1; IRAK-1

    		 Human Sf9 insect cells
    IRAK1 is a serine/threonine protein kinase that initiates innate immune responses against pathogens through Toll-like receptor (TLR) and IL-1R signaling. After TLR activation, IRAK1 is recruited by MYD88 and undergoes IRAK4 phosphorylation, autophosphorylation, and kinase activation. IRAK1 Protein, Human (Sf9, GST) is the recombinant human-derived IRAK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of IRAK1 Protein, Human (Sf9, GST) is 519 a.a., .
  • HY-P72566
    IL-1RA/IL-1RN Protein, Mouse
    5 Publications Verification

    IL-1RN; IL-1ra; IRAP; interleukin-1 Receptor Antagonist Protein

    		 Mouse E. coli
    IL-1RN protein serves as an anti-inflammatory antagonist, targeting proinflammatory cytokines IL1B and IL1A within the interleukin-1 family. Playing a protective role, it prevents immune dysregulation and systemic inflammation induced by IL1, particularly in response to innate stimulatory agents. IL-1RN's regulatory activity contributes to a balanced immune response, safeguarding the host from the detrimental effects of excessive inflammation. IL-1RA/IL-1RN Protein, Mouse is the recombinant mouse-derived IL-1RA/IL-1RN protein, expressed by E. coli , with tag free. The total length of IL-1RA/IL-1RN Protein, Mouse is 152 a.a., with molecular weight of ~18 kDa.
  • HY-P70454G
    GMP IL-1 alpha Protein, Human

    interleukin-1 Alpha; IL-1 Alpha; Hematopoietin-1; IL1A; IL1F1

    		 Human E. coli
    IL-1 alpha is a ubiquitous and pivotal pro-inflammatory cytokine. IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha plays an important role in inflammation and bridges the innate and adaptive immune systems. IL-1 alpha mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways. GMP IL-1 alpha Protein, Human is a recombinant protein consisting of 153 amino acids (A117-S269) and is produced by E. coli.
  • HY-P73146
    IL-1 beta Protein, Canine

    interleukin-1 beta; IL-1β; IL1F2; IL-1 beta; IL1B

    		 Canine E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions. IL-1 beta Protein, Canine consists of 152 amino acids (A115-S266) and is expressed in E. coli.
  • HY-P73147
    IL-1 beta Protein, Cynomolgus

    interleukin-1 beta; IL-1β; IL1F2; IL-1 beta; IL1B

    		 Cynomolgus E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions. IL-1 beta Protein, Cynomolgus consists of 153 amino acids (A117-S269) and is expressed in E. coli.
  • HY-P73148
    IL-1 beta Protein, Feline

    interleukin-1 beta; IL-1β; IL1F2; IL-1 beta; IL1B

    		 Cat E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions. IL-1 beta Protein, Feline consists of 152 amino acids (A116-S267) and is expressed in E. coli.
  • HY-P73150
    IL-1 beta Protein, Rabbit

    interleukin-1 beta; IL-1β; IL1F2; IL-1 beta; IL1B

    		 Rabbit E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions. IL-1 beta Protein, Rabbit consists of 152 amino acids (A117-S268) and is expressed in E. coli.
  • HY-P78143
    IL-1 beta Protein, Human (Biotinylated, His-Avi)

    interleukin-1 beta; IL-1 beta; IL1F2; IL1B; IL-1BETA; IL1F2; IL-1β; IL-1 beta; IL-1B ; interleukin-1 β; IL-1 β; IL-1β; IL-1 β

    		 Human E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions.  IL-1 beta Protein, Human (Biotinylated, His-Avi), a Biotinylated  IL-1 beta protein, is produced in  E. coli with a C-Terminal His-tag and a C-Terminal Avi-tag. It consists of 153 amino acids (A117-S269).
  • HY-P78459
    IL-1 beta Protein, Human (His-Avi)

    interleukin-1 beta; IL-1 beta; IL1F2; IL1B; IL-1BETA; IL1F2; IL-1β; IL-1 beta; IL-1B ; interleukin-1 β; IL-1 β; IL-1β; IL-1 β

    		 Human E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions.  IL-1 beta Protein, Human (His-Avi) is produced in  E. coli with a C-Terminal His-tag and a C-Terminal Avi-tag. It consists of 153 amino acids (A117-S269).
  • HY-P700096AF
    Animal-Free IL-1 beta Protein, Human (His)

    interleukin-1 beta; IL-1 beta; IL1F2; IL1B; IL-1BETA; IL1F2; IL-1β; IL-1 beta; IL-1B ; interleukin-1 β; IL-1 β; IL-1β; IL-1 β

    		 Human E. coli
    IL-1 beta protein is a potent proinflammatory cytokine that plays multiple roles in immune responses. It induces inflammatory events including prostaglandin synthesis, neutrophil activation, and cytokine production. Animal-Free IL-1 beta Protein, Human (His) is the recombinant human-derived animal-FreeIL-1 beta protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-1 beta Protein, Human (His) is 153 a.a., with molecular weight of ~18.48 kDa.
  • HY-P700254
    IL-1beta Protein, Human (153aa, His)

    interleukin-1 beta; IL-1 beta; IL1F2; IL1B; IL-1BETA; IL1F2; IL-1β; IL-1 beta; IL-1B ; interleukin-1 β; IL-1 β; IL-1β; IL-1 β

    		 Human E. coli
    IL-1 beta protein is a potent proinflammatory cytokine that plays multiple roles in immune responses. It induces inflammatory events including prostaglandin synthesis, neutrophil activation, and cytokine production. IL-1beta Protein, Human (153aa, His) is the recombinant human-derived IL-1beta protein, expressed by E. coli , with N-6*His labeled tag. The total length of IL-1beta Protein, Human (153aa, His) is 153 a.a., with molecular weight of approximately 18 kDa.
  • HY-P700888
    IL-1 beta Protein, Cynomolgus (C-His)

    interleukin-1 beta; IL-1 beta; IL1F2; IL1B; IL-1BETA; IL1F2; IL-1β; IL-1 beta; IL-1B ; interleukin-1 β; IL-1 β; IL-1β; IL-1 β

    		 Cynomolgus E. coli
    IL-1 beta Protein, a potent pro-inflammatory cytokine and endogenous pyrogen, induces diverse responses, including prostaglandin synthesis, neutrophil and T-cell activation, B-cell activation, and fibroblast proliferation. It promotes Th17 differentiation, synergizes with IL12 for Th1 IFNG synthesis, and contributes to angiogenesis by inducing VEGF production with TNF and IL6. Involved in pyroptosis, its mature form is released through the GSDMD pore. Existing as a monomer, IL-1 beta Protein interacts with MEFV. IL-1 beta Protein, Cynomolgus (C-His) is the recombinant cynomolgus-derived IL-1 beta protein, expressed by E. coli, with C-His labeled tag. The total length of IL-1 beta Protein, Cynomolgus (C-His) is 152 a.a., with molecular weight of 18.33 kDa.
  • HY-P78459A
    IL-1 beta Protein, Human (C-His)

    interleukin-1 beta; IL-1 beta; IL1F2; IL1B; IL-1BETA; IL1F2; IL-1β; IL-1 beta; IL-1B ; interleukin-1 β; IL-1 β; IL-1β; IL-1 β

    		 Human E. coli
    IL-1 beta protein is a potent proinflammatory cytokine that plays multiple roles in immune responses. It induces inflammatory events including prostaglandin synthesis, neutrophil activation, and cytokine production. IL-1 beta Protein, Human (C-His) is the recombinant human-derived IL-1 beta protein, expressed by E. coli , with C-6*His labeled tag. The total length of IL-1 beta Protein, Human (C-His) is 153 a.a., with molecular weight of ~19.0 kDa.
  • HY-P73894
    IL-1RA/IL-1RN Protein, Rat (His)

    interleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; Il1rn

    		 Rat E. coli
    The IL-1RA/IL-1RN mutant protein, an enhanced anti-inflammatory antagonist in the interleukin-1 family, specifically targets proinflammatory cytokines IL1B and IL1A. Engineered for increased inhibitory capabilities, this mutant variant critically safeguards the host from immune dysregulation and prevents uncontrolled systemic inflammation triggered by IL1 in response to innate stimulatory agents. Offering optimized defense against IL1-mediated inflammation, the mutant protein significantly contributes to maintaining immune balance and preventing excessive inflammation. IL-1RA/IL-1RN Protein, Rat (His) is the recombinant rat-derived IL-1RA/IL-1RN protein, expressed by E. coli, with C-His labeled tag. The total length of IL-1RA/IL-1RN Protein, Rat (His) is 152 a.a., with molecular weight of ~19.01 kDa.
  • HY-P76998
    IL1RAPL1 Protein, Mouse (HEK293, Fc)

    interleukin-1 Receptor Accessory Protein-Like 1; Oligophrenin-4; OPHN4

    		 Mouse HEK293
    IL1RAPL1 protein inhibits N-type calcium channels, regulates secretion, and activates JNK signaling. It promotes neurite growth and bidirectionally induces presynaptic and postsynaptic differentiation by binding to PTPRD during dendritic spine formation. IL1RAPL1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IL1RAPL1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IL1RAPL1 Protein, Mouse (HEK293, Fc) is 333 a.a., with molecular weight of ~85-95 kDa.
  • HY-P700290
    IL-1 alpha Protein, Human (HEK293, Fc)

    interleukin-1 Alpha; IL-1 Alpha; Hematopoietin-1; IL1A; IL1F1

    		 Human HEK293
    IL-1 alpha protein is located in cells and is a key cytokine connecting innate immunity and adaptive immunity. After binding to IL1R1 through IL1RAP, it forms a high-affinity receptor complex, initiates a signaling cascade with adapter molecules such as MYD88, IRAK1 or IRAK4, and activates the NF-kappa-B and MAPK pathways. IL-1 alpha Protein, Human (HEK293, Fc) is the recombinant human-derived IL-1 alpha protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IL-1 alpha Protein, Human (HEK293, Fc) is 159 a.a., with molecular weight of 54 kDa.
  • HY-P73255
    IRAK4 Protein, Human (sf9, His)

    interleukin-1 receptor-associated kinase 4; IPD1; IRAK4; NY-REN-64; REN64

    		 Human Sf9 insect cells
    IRAK4 Protein, a serine/threonine-protein kinase, is pivotal in initiating innate immune responses via Toll-like receptor (TLR) and IL-1R signaling pathways. Upon TLR activation, it rapidly forms the Myddosome with IRAK2. IRAK4 phosphorylates IRAK1, promoting its autophosphorylation, and phosphorylates Pellino proteins to facilitate IRAK1 polyubiquitination. This leads to NF-kappa-B activation and regulates immune responses during microbial infections. Additionally, it phosphorylates TIRAP, influencing its ubiquitination and degradation. IRAK4 Protein, Human (sf9, His) is the recombinant human-derived IRAK4 protein, expressed by Sf9 insect cells , with N-10*His labeled tag. The total length of IRAK4 Protein, Human (sf9, His) is 460 a.a., with molecular weight of ~48 kDa.
  • HY-P75853
    IL-1RA/IL-1RN mutant Protein, Cynomolgus (His)

    interleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; Il1rn

    		 Cynomolgus E. coli
    The IL-1RA/IL-1RN mutant protein, an enhanced anti-inflammatory antagonist in the interleukin-1 family, specifically targets proinflammatory cytokines IL1B and IL1A. Engineered for increased inhibitory capabilities, this mutant variant critically safeguards the host from immune dysregulation and prevents uncontrolled systemic inflammation triggered by IL1 in response to innate stimulatory agents. Offering optimized defense against IL1-mediated inflammation, the mutant protein significantly contributes to maintaining immune balance and preventing excessive inflammation. IL-1RA/IL-1RN mutant Protein, Cynomolgus (His) is the recombinant cynomolgus-derived IL-1RA/IL-1RN mutant protein, expressed by E. coli, with C-10*His labeled tag. The total length of IL-1RA/IL-1RN mutant Protein, Cynomolgus (His) is 152 a.a., with molecular weight of ~18.63 kDa.
  • HY-P700243AF
    Animal-Free IL-1 beta Protein, Pig (His)

    interleukin-1 beta; IL-1β; IL1F2; IL-1 beta; IL1B

    		 Pig E. coli
    IL-1 beta Protein, a potent pro-inflammatory cytokine, initiates various immune responses, including prostaglandin synthesis, neutrophil recruitment, T-cell cytokine production, B-cell activation, fibroblast proliferation, and collagen production. It promotes Th17 differentiation, synergizes with IL12 for IFNG synthesis by Th1 cells, and induces angiogenesis along with TNF and IL6. Involved in pyroptosis, its mature form is released through the GSDMD pore. Additionally, IL-1 beta Protein interacts with ASFV protein L83L during microbial infections. Animal-Free IL-1 beta Protein, Pig (His) is the recombinant pig-derived animal-FreeIL-1 beta protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free IL-1 beta Protein, Pig (His) is 153 a.a., with molecular weight of ~18.51 kDa.
  • HY-P73894A
    IL-1RA/IL-1RN Protein, Rat (C-His)

    interleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; Il1rn

    		 Rat E. coli
    The IL-1RA/IL-1RN mutant protein, an enhanced anti-inflammatory antagonist in the interleukin-1 family, specifically targets proinflammatory cytokines IL1B and IL1A. Engineered for increased inhibitory capabilities, this mutant variant critically safeguards the host from immune dysregulation and prevents uncontrolled systemic inflammation triggered by IL1 in response to innate stimulatory agents. Offering optimized defense against IL1-mediated inflammation, the mutant protein significantly contributes to maintaining immune balance and preventing excessive inflammation. IL-1RA/IL-1RN Protein, Rat (C-His) is the recombinant rat-derived IL-1RA/IL-1RN protein, expressed by E. coli, with C-6*His labeled tag. The total length of IL-1RA/IL-1RN Protein, Rat (C-His) is 152 a.a., with molecular weight of ~19.94 kDa.
  • HY-P70702
    IL-36 alpha/IL-1F6 Protein, Human (153a.a)

    IL-36 alpha; IL-36α; interleukin-36 Alpha; FIL1 Epsilon; interleukin-1 Epsilon; IL-1 Epsilon; interleukin-1 Family Member 6; IL-1F6; IL36A; FIL1E; IL1E; IL1F6

    		 Human E. coli
    IL-36 alpha (IL-1F6), a subform of IL-36 family, belongs to IL-1 superfamily. IL-36 alpha mediates inflammatory response. IL-36 alpha binds to IL-36R and activates NF-κB and MAPK signaling pathways, but the activation requires N-terminal cleavage by neutrophil granule-derived proteases. IL-36 alpha also binds to IL-1Rrp2 and recruit IL-1RAcP. IL-36 alpha activats the MAPK, Erk1/2 and JNK through IL-36R/IL-1RAcP. IL-36 alpha/IL-1F6 Protein, Human (153a.a) is a recombinant human IL-36 alpha (K6-F158) without any tag, which is produced in E. coli.
  • HY-P700126AF
    Animal-Free IL-36 alpha/IL-1F6 Protein, Human (His)

    IL-36 alpha; IL-36α; interleukin-36 Alpha; FIL1 Epsilon; interleukin-1 Epsilon; IL-1 Epsilon; interleukin-1 Family Member 6; IL-1F6; IL36A; FIL1E; IL1E; IL1F6

    		 Human E. coli
    IL-36 α/IL-1F6 protein binds to IL1RL2/IL-36R receptor, activates NF-kappa-B and MAPK pathways, and induces pro-inflammatory responses. IL-36 α/IL-1F6 also upregulates CD83, CD86, and HLA-DR in dendritic cells, promotes dendritic cell maturation, and drives T cell proliferation. Animal-Free IL-36 alpha/IL-1F6 Protein, Human (His) is the recombinant human-derived animal-FreeIL-36 alpha/IL-1F6 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-36 alpha/IL-1F6 Protein, Human (His) is 153 a.a., with molecular weight of ~18.05 kDa.
  • HY-P70642
    IL-18 Protein, Mouse (His)
    1 Publications Verification

    interleukin-18; Il18; Interferon gamma-inducing factor; IFN-gamma-inducing factor; interleukin-1 gamma; IL-1 gamma; Igif

    		 Mouse E. coli
    IL-18 protein is a pro-inflammatory cytokine that plays an important role in epithelial barrier repair and immune response regulation by polarizing T helper 1 (Th1) cells and natural killer (NK) cells. After binding to IL18R1 and IL18RAP receptors, IL-18 forms a signaling ternary complex, activates NF-κ-B, and induces inflammatory mediators. IL-18 Protein, Mouse (His) is the recombinant mouse-derived IL-18 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IL-18 Protein, Mouse (His) is 157 a.a., with molecular weight of ~20.0 kDa.
  • HY-P71601
    IL-1F10/IL-38 Protein, Mouse (His-SUMO)

    Il1f10; interleukin-1 family member 10; IL-1F10

    		 Mouse E. coli
    IL-1F10/IL-38 proteins regulate immune responses. IL-1F10/IL-38 Protein, Mouse (His-SUMO) is the recombinant mouse-derived IL-1F10/IL-38 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of IL-1F10/IL-38 Protein, Mouse (His-SUMO) is 152 a.a., with molecular weight of ~35 kDa.
  • HY-P73149
    IL-1 beta Protein, Human (E6K, His)
    4 Publications Verification

    interleukin-1 beta; IL-1β; IL1F2; IL-1 beta; IL1B

    		 Human E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions.  IL-1 beta Protein, Human (E6K, His) is produced in  E. coli with a N-Terminal His-tag. It consists of 269 amino acids (M1-S269).

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