IRAK inhibitor 3
Based on 1 publication(s) in Google Scholar
IRAK inhibitor 3 is an interleukin-1 (IL-I) receptor-associated kinase (IRAK) kinase modulator extracted from patent WO2008030579 A2.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.86%
- No. CAS: 1012343-93-9
- Fòrmula: C21H21N5O4S
- Peso molecular:439.49
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) IRAK inhibitor 3
More
Actividad biológica
Descripciòn
IC50 & Target
IRAK[1]
In Vitro
IRAK inhibitor 3 is an IRAK modulator, which can be used for treating an inflammatory condition, cell proliferative disorder, immune disorder[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1012343-93-9
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Appearance Solid
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Peso molecular 439.49
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Fòrmula C21H21N5O4S
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Color Off-white to gray
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SMILES
O=S(C1=CC=C(CNC2=NN3C(C4=CC(OC)=C(C=C4)OC)=CN=C3C=C2)C=C1)(N)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
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Neurotherapeutics
α7-Acetylcholine Receptor Signaling Reduces Neuroinflammation After Subarachnoid Hemorrhage in Mice. [Abstract]2021 Jul;18(3):1891-1904. PMID: 33970466
Solvente y solubilidad
In Vitro:
DMSO : 13 mg/mL (29.58 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2754 mL | 11.3768 mL | 22.7536 mL | 56.8841 mL |
| 5 mM | 0.4551 mL | 2.2754 mL | 4.5507 mL | 11.3768 mL | |
| 10 mM | 0.2275 mL | 1.1377 mL | 2.2754 mL | 5.6884 mL | |
| 15 mM | 0.1517 mL | 0.7585 mL | 1.5169 mL | 3.7923 mL | |
| 20 mM | 0.1138 mL | 0.5688 mL | 1.1377 mL | 2.8442 mL | |
| 25 mM | 0.0910 mL | 0.4551 mL | 0.9101 mL | 2.2754 mL |
IRAK inhibitor 3 Related Classifications
HY-13277 Related Classifications
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