IX 207-887
Based on 1 Customer Validation
IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).
For research use only. We do not sell to patients.
- Purity: 98.96%
- CAS No.: 98320-39-9
- Formula: C16H12O3S
- Molecular Weight:284.33
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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IL-2 |
IL-1 |
IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 98320-39-9
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Appearance Solid
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Molecular Weight 284.33
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Formula C16H12O3S
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Color Light yellow to yellow
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SMILES
OC(/C=C1C2=C(SC=C2)C(OC)=CC3=C\1C=CC=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (351.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.5170 mL | 17.5852 mL | 35.1704 mL | 87.9260 mL |
| 5 mM | 0.7034 mL | 3.5170 mL | 7.0341 mL | 17.5852 mL | |
| 10 mM | 0.3517 mL | 1.7585 mL | 3.5170 mL | 8.7926 mL | |
| 15 mM | 0.2345 mL | 1.1723 mL | 2.3447 mL | 5.8617 mL | |
| 20 mM | 0.1759 mL | 0.8793 mL | 1.7585 mL | 4.3963 mL | |
| 25 mM | 0.1407 mL | 0.7034 mL | 1.4068 mL | 3.5170 mL | |
| 30 mM | 0.1172 mL | 0.5862 mL | 1.1723 mL | 2.9309 mL | |
| 40 mM | 0.0879 mL | 0.4396 mL | 0.8793 mL | 2.1982 mL | |
| 50 mM | 0.0703 mL | 0.3517 mL | 0.7034 mL | 1.7585 mL | |
| 60 mM | 0.0586 mL | 0.2931 mL | 0.5862 mL | 1.4654 mL | |
| 80 mM | 0.0440 mL | 0.2198 mL | 0.4396 mL | 1.0991 mL | |
| 100 mM | 0.0352 mL | 0.1759 mL | 0.3517 mL | 0.8793 mL |
IX 207-887 Related Classifications
HY-106087 Related Classifications
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