1. Immunology/Inflammation
  2. Interleukin Related

IX 207-887 

Cat. No.: HY-106087
Handling Instructions

IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).

For research use only. We do not sell to patients.

IX 207-887 Chemical Structure

IX 207-887 Chemical Structure

CAS No. : 98320-39-9

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  • Biological Activity

  • Technical Information

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  • References

Description

IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).

IC50 & Target

Interleukin-1[1]

In Vitro

IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5170 mL 17.5852 mL 35.1704 mL
5 mM 0.7034 mL 3.5170 mL 7.0341 mL
10 mM 0.3517 mL 1.7585 mL 3.5170 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

284.33

Formula

C₁₆H₁₂O₃S

CAS No.

98320-39-9

SMILES

OC(/C=C1C2=C(SC=C2)C(OC)=CC3=C\1C=CC=C3)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
IX 207-887
Cat. No.:
HY-106087
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IX 207-887

Cat. No.: HY-106087