Triptoquinone A
Triptoquinone A, an interleukin 1 inhibitor, inhibits endomycin (LPS) or interleukin (IL-1β)-promoted induction of nitric oxide synthase (NOS) in vascular smooth muscle, thereby inhibiting Arg-induced vascular relaxation.
For research use only. We do not sell to patients.
- CAS No.: 142950-86-5
- Formula: C20H24O4
- Molecular Weight:328.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IL-1β, NOS[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>100 μM
Compound: 10
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 27133593] |
| Bcap37 | IC50 |
>100 μM
Compound: 10
|
Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
|
[PMID: 27133593] |
| Hep 3B2 | IC50 |
>100 μM
Compound: 10
|
Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
|
[PMID: 27133593] |
| HepG2 | IC50 |
>100 μM
Compound: 10
|
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 27133593] |
| MCF7 | IC50 |
>100 μM
Compound: 10
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 27133593] |
| U-251 | IC50 |
>100 μM
Compound: 10
|
Cytotoxicity against human U251 cells after 48 hrs by MTT assay
Cytotoxicity against human U251 cells after 48 hrs by MTT assay
|
[PMID: 27133593] |
Chemical Information
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CAS No. 142950-86-5
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Molecular Weight 328.40
-
Formula C20H24O4
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SMILES
O=C(C1=C(C)[C@]2([H])CCC3=C(C(C=C(C(C)C)C3=O)=O)[C@@]2(C)CC1)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)