IL-1 beta Antibody

Cat. No.: HY-P80720: FAQs
Data Sheet SDS COA User Guide for Antibodies

IL-1 beta Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 31 kDa, targeting to IL-1 beta. It can be used for WB,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size	Price	Stock	Quantity
Free Sample		Apply now
10 μL	$77	In-stock	Estimated Time of Arrival: December 31
50 μL	$200	In-stock	Estimated Time of Arrival: December 31
100 μL	$325	In-stock	Estimated Time of Arrival: December 31
250 μL		Get quote

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Biological Activity
Technical Parameters
Properties
Documentation

Description	IL-1 beta Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 31 kDa, targeting to IL-1 beta. It can be used for WB,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.
Background	IL-1 beta: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. Similarly, IL-1B has been implicated in human osteoarthritis pathogenesis. Patients with severe Coronavirus Disease 2019 (COVID-19) present elevated levels of pro-inflammatory cytokines such as IL-1B in bronchial alveolar lavage fluid samples. The lung damage induced by the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is to a large extent, a result of the inflammatory response promoted by cytokines such as IL-1B. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2020]
Tag	Free
Gene ID	3553
Synonyms	IL1B; IL1F2; Interleukin-1 beta; IL-1 beta; Catabolin
Molecular Weight	Predicted band size: 31 kDa
Purity	affinity purified
Conjugation	Non-conjugated
Research Field	Immunology
Product Categories	Primary Antibody; Rabbit Polyclonal Antibody
Host	Rabbit
Reactivity	Human, Mouse, Rat
SwissProt ID	P01584
Dilution Ratio	WB: 1:500-1:1,000 ;IHC: 1:50-1:100 ;IF: 1:50-1:200
Application	WB, IHC-P, ICC/IF
Appearance	Liquid
Formulation	Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Immunogen	Synthetic peptide corresponding to Human IL1B AA range 181-230.
Documentation	Select Batch: Data Sheet (235 KB) SDS (0 KB) COA (191 KB) User Guide for Antibodies (1077 KB)

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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IL-1 beta Antibody

Biological Activity

Technical Parameters

Properties

Documentation

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