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Potassium diphosphate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Potassium Channel (12) Adenylate Cyclase (2) Adrenergic Receptor (1) Akt (3) Amino Acid Derivatives (1) Antibiotic (4) Apoptosis (17) ATP Synthase (2) ATP-binding cassette (ABC) transporters (2) Autophagy (8) Bacterial (15) Biochemical Assay Reagents (30) Btk (1) c-Kit (2) c-Myc (3) Calcium Channel (6) Caspase (5) CD38 (1) CD73 (5) CHIKV (2) CMV (3) COX (1) DNA/RNA Synthesis (16) Dopamine Receptor (1) Drug Derivative (5) Drug Intermediate (4) Drug Metabolite (5) Endogenous Metabolite (85) Enterovirus (4) Environmental Pollutants (1) Estrogen Receptor/ERR (1) Farnesyl Transferase (9) Fluorescent Dye (1) Fructose-1,6-bisphosphate aldolase (1) Fungal (1) GSK-3 (1) HBV (2) HCV (7) Hepcidin (5) Histamine Receptor (2) HIV (9) HIV Integrase (5) HSP (2) HSV (2) Interleukin Related (2) Isotope-Labeled Compounds (34) MicroRNA (1) Microtubule/Tubulin (1) NTPDase (1) Nuclear Factor of activated T Cells (NFAT) (1) Nucleoside Antimetabolite/Analog (13) OAT (6) Orthopoxvirus (1) Oxidative Phosphorylation (1) P-glycoprotein (1) P2Y Receptor (21) p38 MAPK (2) Parasite (13) PARP (1) Phosphatase (2) Phospholipase (1) Phosphorylase (1) PI3K (1) PKC (1) Platelet-activating Factor Receptor (PAFR) (5) Prostaglandin Receptor (4) PROTAC-Linker Conjugates for PAC (1) Pyruvate Kinase (3) Ras (3) Reactive Oxygen Species (ROS) (8) Reference Standards (20) Reverse Transcriptase (5) SARS-CoV (14) Smo (1) STAT (2) Toll-like Receptor (TLR) (8) Topoisomerase (2) Transketolase (3) TRP Channel (8) VEGFR (2) YAP (1) β-glucuronidase (1)
By Research Areas:	Cancer (64) Cardiovascular Disease (34) Endocrinology (3) Infection (69) Inflammation/Immunology (46) Metabolic Disease (49) Neurological Disease (21)
Click Chemistry:	Azide (1)
Oligonucleotides:	Guanine Nucleotide (1) Inosine Nucleoside (1) Nucleoside Analogs (3) Nucleotide Analogs (22) Uracil Nucleotide (1) Cytidine Nucleotide (3) Adenine Nucleotide (8)

291

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GMP Molecules

Targets Recommended: Potassium Channel UGT Na+/K+ ATPase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010918

Adenosine 5'-diphosphate Maximum Cited Publications 9 Publications Verification Adenosine diphosphate; ADP	Endogenous Metabolite	Others
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-113066A

*Guanosine 5'-diphosphate* disodium salt** 2 Publications Verification GDP disodium salt	Hepcidin Potassium Channel Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-W010832

*Uridine-5'-diphosphate* disodium salt** 2 Publications Verification	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Uridine-5'-diphosphate disodium salt is a potent, selective P2Y₆ receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52 for human P2Y₆ receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-12651

Primaquine diphosphate 5+ Cited Publications Primaquine phosphate; Primaquine bisphosphate	Parasite	Infection Cancer
Primaquine diphosphate is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine diphosphate prevents relapse in vivax and ovale malaria .

HY-113066C

*Guanosine 5'-diphosphate* sodium, 96% (HPLC)** 2 Publications Verification GDP sodium, Type I, 96% (HPLC)	Hepcidin Potassium Channel Endogenous Metabolite Interleukin Related STAT	Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (GDP) sodium, 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, 96% (HPLC) is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate sodium, 96% (HPLC) ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate sodium, 96% (HPLC) can be used in the research of AI .

HY-D0199

*Adenosine 5'-diphosphate* disodium** Maximum Cited Publications 9 Publications Verification Adenosine diphosphate disodium; ADP disodium	Endogenous Metabolite	Cardiovascular Disease
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-B1831A

Oritavancin diphosphate 2 Publications Verification LY333328 diphosphate	Bacterial Antibiotic	Infection Inflammation/Immunology
Oritavancin diphosphate (LY333328 diphosphate), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .

HY-114295A

*Geranyl diphosphate* triammonium** Geranyl pyrophosphate triammonium	Endogenous Metabolite	Metabolic Disease
Geranyl diphosphate triammonium is a key intermediate in the isoprenoid biosynthesis pathway (IBP). Geranyl diphosphate triammonium plays key roles in cellular metabolism and is responsible for the production of both sterol and non-sterol isoprenoids .

HY-136548B

*Tenofovir diphosphate* disodium** TFV-DP disodium	HIV Reverse Transcriptase	Infection Inflammation/Immunology
Tenofovir diphosphate disodium is an antiretroviral agent. Tenofovir diphosphate disodium is an inhibitor of HIV reverse transcriptase DNA (K_i = 1.55 μM) and RNA (K_i = 0.022 μM). Tenofovir diphosphate disodium can be used for the research of AIDS .

HY-16582

Sonidegib diphosphate 10+ Cited Publications Erismodegib diphosphate; LDE225 diphosphate; NVP-LDE225 diphosphate	Smo	Cancer
Sonidegib diphosphate (Erismodegib diphosphate) is a potent and selective Smo antagonist with IC₅₀ of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .

HY-W010791

*Adenosine 5'-diphosphate* sodium salt** Maximum Cited Publications 9 Publications Verification	Endogenous Metabolite	Others
Adenosine 5'-diphosphate sodium salt is a nucleoside diphosphate and the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase through its action on P_2T-purinergic receptors .

HY-113066

Guanosine 5'-diphosphate GDP	Hepcidin Potassium Channel Endogenous Metabolite Interleukin Related STAT	Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate can be used in the research of AI .

HY-10229

Motesanib Diphosphate 4 Publications Verification AMG 706 diphosphate	c-Kit VEGFR	Cancer
Motesanib Diphosphate (AMG 706 Diphosphate) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC₅₀s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is approximately 10-fold more selective for VEGFR than PDGFR and Ret.

HY-112889B

*Oxythiamine diphosphate* ammonium** 1 Publications Verification	Transketolase	Metabolic Disease
Oxythiamin diphosphate ammonium is a potent transketolase (TK) inhibitor .

HY-W013724

*Inosine-5'-diphosphate* disodium** IDP disodium; Inosine-5'-diphosphoric acid disodium	c-Myc Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Inosine-5'-diphosphate disodium (IDP disodium) is a decoy substrate of NM23-H2. Inosine-5'-diphosphate disodium has a superior bond capacity on GDP-binding pocket of NM23-H2 (K_D: 5.0 μM). Inosine-5'-diphosphate disodium abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate disodium has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate disodium can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research .

HY-136548

Tenofovir diphosphate TFV-DP	Reverse Transcriptase HIV	Infection Inflammation/Immunology
Tenofovir diphosphate is an antiretroviral agent. Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase DNA (K_i = 1.55 μM) and RNA (K_i = 0.022 μM). Tenofovir diphosphate can be used for the research of AIDS .

HY-W010820

*Uridine 5'-diphosphate* sodium salt** 2 Publications Verification	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Uridine 5'-diphosphate sodium salt is a potent, selective P2Y₆ receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52) and a potent P2Y₁₄ antagonist (pEC₅₀=7.28). Uridine 5'-diphosphate sodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-W008915

*Cytidine 5'-diphosphate* trisodium salt** CDP	DNA/RNA Synthesis	Metabolic Disease
Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA .

HY-112889

Oxythiamine diphosphate	Transketolase	Metabolic Disease
Oxythiamin diphosphate is a potent transketolase (TK) inhibitor .

HY-137243

*Adenosine 3',5'-diphosphate* disodium**	Endogenous Metabolite Nucleoside Antimetabolite/Analog	Others
Adenosine 3',5'-diphosphate disodium is an endogenous purine nucleotide. Adenosine 3',5'-diphosphate disodium acts as an inhibitor of bovine adrenal estrogen sulfotransferase (EST) with a K_i value of 7.0 μM. It also serves as an indispensable specific cofactor for the pregnenolone-binding protein (PBP) steroid-binding complex, with an EC₅₀ value of 1.5 μM in guinea pigs .

HY-131606B

*Cidofovir diphosphate* tritriethylamine**	Drug Metabolite DNA/RNA Synthesis	Infection
Cidofovir diphosphate tri triethylamine is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate tri triethylamine is a selective inhibitor of viral DNA polymerases with K_i values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively .

HY-106254A

Vapendavir diphosphate 4 Publications Verification BTA798 diphosphate	Enterovirus	Infection Inflammation/Immunology
Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC₅₀ values of 0.5-1.4 μM in different EV71 strains .

HY-131576A

*Thymidine 5′-diphosphate* sodium** dTDP sodium	Endogenous Metabolite	Metabolic Disease
Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-113359

Uridine 5'-diphosphate UDP	P2Y Receptor Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Uridine 5'-diphosphate (UDP) is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor .

HY-149101

Inosine-5'-diphosphate IDP; Inosine-5'-diphosphoric acid	c-Myc Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Inosine-5'-diphosphate (IDP) is a decoy substrate of NM23-H2. Inosine-5'-diphosphate has a superior bond capacity on GDP-binding pocket of NM23-H2 (K_D: 5.0 μM). Inosine-5'-diphosphate abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research .

HY-147358

Yimitasvir diphosphate Emitasvir diphosphate; DAG-181 diphosphate	HCV	Infection
Yimitasvir diphosphate (Emitasvir diphosphate; DAG-181 diphosphate) is an orally active inhibitor of hepatitis C virus (HCV) nonstructural protein 5A (NS5A). Yimitasvir diphosphate is applicable to research related to HCV infection .

HY-W010918S2

*Adenosine 5'-diphosphate-15N5 dilithium* Adenosine diphosphate-15N5 dilithium; ADP-15N5 dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Adenosine 5'-diphosphate- ¹⁵N₅ (Adenosine diphosphate- ¹⁵N₅ dilithium) dilithium is ¹⁵N labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-115581A

*Thymidine 3',5'-diphosphate* tetrasodium** Deoxythymidine 3′,5′-diphosphate tetrasodium; pdTp tetrasodium	Apoptosis MicroRNA	Cancer
Thymidine 3',5'-diphosphate (Deoxythymidine 3′,5′-diphosphate) tetrasodium is a selective inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the MicroRNA regulatory complex RISC subunit) and [3,5- ²H₂] tyrosyl nuclease. Thymidine 3',5'-diphosphate tetrasodium has anti-tumor activity and can also be used as a catalyst in biochemical reactions .

HY-W010861

*2'-Deoxycytidine-5'-diphosphate* trisodium** 1 Publications Verification dCDP trisodium	Endogenous Metabolite	Metabolic Disease
2'-Deoxycytidine-5'-diphosphate (dCDP) trisodium is an endogenous metabolite.

HY-114327

D-Ribose 1,5-diphosphate R15P	Endogenous Metabolite Drug Intermediate Biochemical Assay Reagents	Others
D-Ribose 1,5-diphosphate (R15P) is a metabolic intermediate and enzyme substrate. Purified Tk-E2b2 converts D-Ribose 1,5-diphosphate into Ribulose-1,5-bisphosphate, with a specific activity of 32.3 μmol min ^-1 mg ^-1[1] .

HY-W010918R

*Adenosine 5'-diphosphate* (Standard)** Adenosine diphosphate (Standard); ADP (Standard)	Reference Standards Endogenous Metabolite	Others
Adenosine 5'-diphosphate (Standard) is the analytical standard of Adenosine 5'-diphosphate. This product is intended for research and analytical applications. Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors. In Vitro: Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.

HY-D0199R

*Adenosine 5'-diphosphate* disodium (Standard)** Adenosine diphosphate disodium (Standard); ADP disodium (Standard)	Endogenous Metabolite Reference Standards	Cardiovascular Disease
Adenosine 5'-diphosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-diphosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-131576

Thymidine 5′-diphosphate dTDP	Endogenous Metabolite	Metabolic Disease
Thymidine 5′-diphosphate (dTDP) is a key product for pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is generated via the phosphorylation of thymidine 5'-monophosphate (dTMP) catalyzed by thymidylate kinase (TMPK), a process requiring ATP and Mg ²⁺. Thymidine 5′-diphosphate is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels enables the assessment of TMPK activity .

HY-W010918S3

*Adenosine 5'-diphosphate-13C5* Adenosine diphosphate-¹³C₅; ADP-¹³C₅	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine 5'-diphosphate- ¹³C₅ (Adenosine diphosphate- ¹³C₅) is the ¹³C-labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.

HY-113066S1

*Guanosine 5'-diphosphate-13C10 dilithium* GDP-13C10 dilithium	Isotope-Labeled Compounds Endogenous Metabolite Potassium Channel	Inflammation/Immunology
Guanosine 5'-diphosphate- ¹³C₁₀ (GDP- ¹³C₁₀) dilithium is ¹³C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-Y1918

Potassium diphosphate tetra-Potassium pyrophosphate	Environmental Pollutants Biochemical Assay Reagents	Others
Potassium diphosphate (tetra-Potassium pyrophosphate) is a kind of biological materials or organic compounds that are widely used in life science research .

HY-P2881

*Nucleoside diphosphate* kinase** Nucleoside 5′-diphosphate kinase	Biochemical Assay Reagents	Cancer
Nucleoside diphosphate kinase (Nucleoside 5′-diphosphate kinase) belongs to the family of structurally and functionally conserved NDPK (Nucleotide diphosphate kinase) enzymes. Nucleoside diphosphate kinase catalyzes the reversible transfer of γ-phosphates between nucleoside di-(NDP) and triphosphates (NTP) through ping-pong bi-bi reaction kinetics. Nucleoside diphosphate kinase is the essential housekeeping proteins that produces CTP (cytidine triphosphate) for lipid syntheses, UTP (Uridine triphosphate) for polysaccharide syntheses, and GTP (guanosine triphosphate) for protein syntheses, signal transduction, and microtubules polymerization .

HY-135811A

Desethyl chloroquine diphosphate 2 Publications Verification	Parasite Toll-like Receptor (TLR) Autophagy	Infection
Desethyl chloroquine diphosphate is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine diphosphate possesses antiplasmodic activity .

HY-W008915R

*Cytidine 5'-diphosphate* trisodium salt (Standard)** CDP (Standard)	Reference Standards DNA/RNA Synthesis	Metabolic Disease
Cytidine 5'-diphosphate (trisodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (trisodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2].

HY-128606

*Thiamine diphosphate* analog 1**	Endogenous Metabolite Transketolase	Neurological Disease Metabolic Disease
Thiamine diphosphate analog 1 is an analog of thiamine diphosphate. Thiamine diphosphate is the active metabolite of vitamin B₁ in organisms. Thiamine diphosphate targets ThDP-dependent enzymes such as transketolase and pyruvate dehydrogenase complex, acting as an essential coenzyme to exert an activating effect. Thiamine diphosphate assists in catalytic reactions in free form and initiates the catalytic cycles of various glucose-metabolizing enzymes. Thiamine diphosphate serves as a diagnostic biomarker and protective factor for Alzheimer's disease. Thiamine diphosphate can be used in research related to metabolism and Alzheimer's disease .

HY-113066AR

*Guanosine 5'-diphosphate* disodium salt (Standard)** GDP disodium salt (Standard)	Hepcidin Endogenous Metabolite Potassium Channel Reference Standards	Neurological Disease Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-131606

Cidofovir diphosphate	HSV CMV DNA/RNA Synthesis	Infection
Cidofovir diphosphate is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate is a selective inhibitor of viral DNA polymerases with K_i values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively .

HY-12651R

*Primaquine diphosphate* (Standard)** Primaquine phosphate (Standard); Primaquine bisphosphate (Standard)	Reference Standards Parasite	Infection Cancer
Primaquine (diphosphate) (Standard) is the analytical standard of Primaquine (diphosphate). This product is intended for research and analytical applications. Primaquine diphosphate is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine diphosphate prevents relapse in vivax and ovale malaria .

HY-113066S

*Guanosine 5'-diphosphate-15N5 dilithium* GDP-15N5 dilithium	Isotope-Labeled Compounds Endogenous Metabolite Potassium Channel	Inflammation/Immunology
Guanosine 5'-diphosphate- ¹⁵N₅ (GDP- ¹⁵N₅) dilithium is ¹⁵N labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-154828

Uridine 3′,5′-diphosphate 3′,5′-UDP	DNA/RNA Synthesis	Others
Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) is a competitive RNase inhibitor .

HY-129887

*Fluorescein diphosphate* tetraammonium**	Fluorescent Dye	Others
Fluorescein diphosphate tetraammonium is a fluorescent dye, it can be used as a fluorogenic substrate and generats fluorescein as a fluorescent product .

HY-158359

5′-XDP sodium Xanthosine 5′-diphosphate sodium	Endogenous Metabolite	Others
5’-XDP sodium (Xanthosine 5' -diphosphate sodium) is an ADP analog involved in the synthesis of ribosomes .

HY-113400

Cytidine 5'-diphosphate Cytidine diphosphate	Endogenous Metabolite	Others
Cytidine 5'-diphosphate (Cytidine diphosphate) is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-W749117

*Inosine 5′-diphosphate* sodium**	Endogenous Metabolite	Metabolic Disease
Inosine 5’-diphosphate sodium is a purine ribonucleoside 5’-diphosphate with inosine as the nucleobase, which can participate in intracellular energy metabolism and signal transduction processes .

HY-N7740

*Adenosine 2',5'-diphosphate* sodium**	P2Y Receptor Endogenous Metabolite	Others
Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors .

Cat. No.	Product Name	Type

HY-B0445GL

NAD+ (GMP Like) β-DPN (GMP Like); β-NAD (GMP Like); β-Nicotinamide Adenine Dinucleotide (GMP Like)	Fluorescent Dyes
NAD+ (GMP Like) is NAD+ (HY-B0445) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

HY-129887

*Fluorescein diphosphate* tetraammonium**	Fluorescent Dyes
Fluorescein diphosphate tetraammonium is a fluorescent dye, it can be used as a fluorogenic substrate and generats fluorescein as a fluorescent product .

HY-D3302

PtdIns-(4,5)-P2-biotin sodium DOPI-4,5-P2-biotin sodium; Phosphatidylinositol-4,5-diphosphate C-8-biotin sodium; PI(4,5)P2-biotin sodium	Fluorescent Dyes
PtdIns-(4,5)-P2-biotin (DOPI-4,5-P2-biotin) sodium is a biotin-labeled phosphatidylinositol 4,5-bisphosphate (PIP2) derivative. PtdIns-(4,5)-P2-biotin sodium uses a biotin tag to capture and purify natural PIP2 molecules and their interacting proteins.

Cat. No.	Product Name	Type

HY-113066C

Guanosine 5'-diphosphate sodium, 96% (HPLC)

2 Publications Verification

GDP sodium, Type I, 96% (HPLC)

Biochemical Assay Reagents

Guanosine 5'-diphosphate (GDP) sodium, 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, 96% (HPLC) is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate sodium, 96% (HPLC) ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate sodium, 96% (HPLC) can be used in the research of AI .

HY-D0199

*Adenosine 5'-diphosphate* disodium** Maximum Cited Publications 9 Publications Verification Adenosine diphosphate disodium; ADP disodium	Biochemical Assay Reagents
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-B0445GL

NAD+ (GMP Like) β-DPN (GMP Like); β-NAD (GMP Like); β-Nicotinamide Adenine Dinucleotide (GMP Like)	Biochemical Assay Reagents
NAD+ (GMP Like) is NAD+ (HY-B0445) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

HY-125954A

Uridine diphosphate glucuronic acid ammonium

UDP-α-D-glucuronic acid ammonium

Biochemical Assay Reagents

Uridine diphosphate glucuronic acid ammonium (UDP-α-D-glucuronic acid ammonium) is a glucuronic acid donor. Uridine diphosphate glucuronic acid ammonium transfers its glucuronic acid moiety to acceptor molecules, thereby forming "ether" glucuronides, while being converted into uridine 5'-pyrophosphate. Uridine diphosphate glucuronic acid ammonium serves as a substrate for Arabidopsis UDP-GlcA 4-epimerase 1, and undergoes reversible 4-epimerization to generate UDP-α-D-galacturonic acid .

HY-W010854

2'-Deoxyadenosine 5'-di-phos-phate disodium dADP disodium	Biochemical Assay Reagents
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .

HY-D0199R

Adenosine 5'-diphosphate disodium (Standard)

Adenosine diphosphate disodium (Standard); ADP disodium (Standard)

Biochemical Assay Reagents

Adenosine 5'-diphosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-diphosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-Y1918

Potassium diphosphate tetra-Potassium pyrophosphate	Biochemical Assay Reagents
Potassium diphosphate (tetra-Potassium pyrophosphate) is a kind of biological materials or organic compounds that are widely used in life science research .

HY-163967

Clindamycin 2,4-diphosphate	Biochemical Assay Reagents
Clindamycin 2,4-diphosphate is a related impurity of Clindamycin phosphate (HY-B1064), a prodrug of Clindamycin (HY-B1455). Clindamycin phosphate inhibits protein synthesis by targeting the bacterial ribosomal 50S subunit .

HY-163973

α-D-Glucopyranosyl β-D-arabino-2-hexulofuranosidonic acid	Biochemical Assay Reagents
Clindamycin 2,4-diphosphate is a biochemical assay reagent.

HY-W127689

Bistetrabutylammonium dihydrogen pyrophosphate Bistetrabutylammonium dihydrogen diphosphate	Biochemical Assay Reagents
Bis(tetrabutylammonium) Dihydrogen Pyrophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-164112

*1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium* 18:1 CDP DG	Biochemical Assay Reagents
1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium (18:1 CDP DG) is a diacylglycerol derivate .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010918

Adenosine 5'-diphosphate Maximum Cited Publications 9 Publications Verification Adenosine diphosphate; ADP	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-B0445

NAD+ Maximum Cited Publications 45 Publications Verification β-DPN; β-NAD; β-Nicotinamide Adenine Dinucleotide	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

HY-113066A

*Guanosine 5'-diphosphate* disodium salt** 2 Publications Verification GDP disodium salt	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Hepcidin Potassium Channel Endogenous Metabolite
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-B0739

Citicoline 4 Publications Verification Cytidine diphosphate-choline; CDP-Choline; Cytidine 5'-diphosphocholine	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Animals Other Alkaloids Plants Endogenous metabolite Source Classification	Apoptosis Endogenous Metabolite Reactive Oxygen Species (ROS) Caspase
Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study .

HY-W010832

*Uridine-5'-diphosphate* disodium salt** 2 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite
Uridine-5'-diphosphate disodium salt is a potent, selective P2Y₆ receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52 for human P2Y₆ receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-113066C

*Guanosine 5'-diphosphate* sodium, 96% (HPLC)** 2 Publications Verification GDP sodium, Type I, 96% (HPLC)	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Hepcidin Potassium Channel Endogenous Metabolite Interleukin Related STAT
Guanosine 5'-diphosphate (GDP) sodium, 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, 96% (HPLC) is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate sodium, 96% (HPLC) ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate sodium, 96% (HPLC) can be used in the research of AI .

HY-A0129

Histamine phosphate 15+ Cited Publications Histamine diphosphate	Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Endogenous metabolite Disease Research Fields Endocrinology Source Classification Cancer	Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine phosphate can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-D0199

*Adenosine 5'-diphosphate* disodium** Maximum Cited Publications 9 Publications Verification Adenosine diphosphate disodium; ADP disodium	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-114295A

*Geranyl diphosphate* triammonium** Geranyl pyrophosphate triammonium	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Geranyl diphosphate triammonium is a key intermediate in the isoprenoid biosynthesis pathway (IBP). Geranyl diphosphate triammonium plays key roles in cellular metabolism and is responsible for the production of both sterol and non-sterol isoprenoids .

HY-113037C

Farnesyl pyrophosphate ammonium Farnesyl diphosphate ammonium	Natural Products Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	TRP Channel Endogenous Metabolite Calcium Channel
Farnesyl pyrophosphate (Farnesyl diphosphate) ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases .

HY-B0739A

Citicoline sodium 4 Publications Verification Cytidine diphosphate-choline sodium; CDP-Choline sodium; Cytidine 5'-diphosphocholine sodium	Alkaloids Structural Classification Microorganisms other families Animals Other Alkaloids Plants Endogenous metabolite Source Classification	Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) Caspase
Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study .

HY-N9474

Mevalonic acid 5-pyrophosphate tetralithium 5-Diphosphomevalonic acid tetralithium; Mevalonic acid 5-diphosphate tetralithium	Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Mevalonic acid 5-pyrophosphate (5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite of the mevalonate pathway .

HY-113066

Guanosine 5'-diphosphate GDP	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Inflammation/Immunology Disease Research Fields Cardiovascular System Disorder Source Classification	Hepcidin Potassium Channel Endogenous Metabolite Interleukin Related STAT
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate can be used in the research of AI .

HY-W010820

*Uridine 5'-diphosphate* sodium salt** 2 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology Source Classification	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite
Uridine 5'-diphosphate sodium salt is a potent, selective P2Y₆ receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52) and a potent P2Y₁₄ antagonist (pEC₅₀=7.28). Uridine 5'-diphosphate sodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-W008915

*Cytidine 5'-diphosphate* trisodium salt** CDP	Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	DNA/RNA Synthesis
Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA .

HY-125954

*Uridine diphosphate* glucuronic acid** UDP-α-D-glucuronic acid	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite
Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a glucuronic acid donor. Uridine diphosphate glucuronic acid transfers its glucuronic acid moiety to acceptor molecules, thereby forming "ether" glucuronides, while being converted into uridine 5'-pyrophosphate. Uridine diphosphate glucuronic acid serves as a substrate for Arabidopsis UDP-GlcA 4-epimerase 1, and undergoes reversible 4-epimerization to generate UDP-α-D-galacturonic acid .

HY-114295

Geranyl diphosphate Geranyl pyrophosphate	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Geranyl diphosphate is a key intermediate in the isoprenoid biosynthesis pathway (IBP). HY-114295 plays key roles in cellular metabolism and is responsible for the production of both sterol and non-sterol isoprenoids .

HY-113037

(E/Z)-Farnesyl pyrophosphate (E/Z)-Farnesyl diphosphate	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	TRP Channel Endogenous Metabolite
(E/Z)-Farnesyl pyrophosphate ((E/Z)-Farnesyl diphosphate), a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. (E/Z)-Farnesyl pyrophosphate is a TRPM2 (TRP Channel) agonist, activates TRPM2 opening for ion influx. (E/Z)-Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis .

HY-130573

DMAPP Dimethylallyl diphosphate	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Plants Maclurodendron oligophlebium (Merrill) T. G. Hartley Endogenous metabolite Disease Research Fields Source Classification Salicaceae	Others
DMAPP (Dimethylallyl pyrophosphate) is an isoprenoid precursor. DMAPP, as an isomer of isopentenyl pyrophosphate (IPP), exists in virtually all life forms .

HY-134891

HMBPP lithium (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium	Natural Products Microorganisms Source Classification	Nuclear Factor of activated T Cells (NFAT)
HMBPP lithium is an intermediate in isoprenoid biosynthesis that can be produced by bacteria and protozoa that use the non-mevalonate pathway for isoprenoid biosynthesis. HMBPP lithium is a ligand of the internal domain of BTN3A1 and is an activator for human Vγ9/Vδ2 T cells. HMBPP lithium exhibits phagostimulant property in mosquitos .

HY-131576A

*Thymidine 5′-diphosphate* sodium** dTDP sodium	Infection Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-113359

Uridine 5'-diphosphate UDP	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	P2Y Receptor Endogenous Metabolite
Uridine 5'-diphosphate (UDP) is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor .

HY-149101

Inosine-5'-diphosphate IDP; Inosine-5'-diphosphoric acid	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	c-Myc Apoptosis
Inosine-5'-diphosphate (IDP) is a decoy substrate of NM23-H2. Inosine-5'-diphosphate has a superior bond capacity on GDP-binding pocket of NM23-H2 (K_D: 5.0 μM). Inosine-5'-diphosphate abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research .

HY-141472

*7-Methylguanosine 5'-diphosphate* sodium** 7-Methyl-GDP sodium; m7GDP sodium	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues .

HY-114327

D-Ribose 1,5-diphosphate R15P	Microorganisms Source Classification	Endogenous Metabolite Drug Intermediate Biochemical Assay Reagents
D-Ribose 1,5-diphosphate (R15P) is a metabolic intermediate and enzyme substrate. Purified Tk-E2b2 converts D-Ribose 1,5-diphosphate into Ribulose-1,5-bisphosphate, with a specific activity of 32.3 μmol min ^-1 mg ^-1[1] .

HY-125954A

*Uridine diphosphate* glucuronic acid ammonium** UDP-α-D-glucuronic acid ammonium	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Uridine diphosphate glucuronic acid ammonium (UDP-α-D-glucuronic acid ammonium) is a glucuronic acid donor. Uridine diphosphate glucuronic acid ammonium transfers its glucuronic acid moiety to acceptor molecules, thereby forming "ether" glucuronides, while being converted into uridine 5'-pyrophosphate. Uridine diphosphate glucuronic acid ammonium serves as a substrate for Arabidopsis UDP-GlcA 4-epimerase 1, and undergoes reversible 4-epimerization to generate UDP-α-D-galacturonic acid .

HY-N0097R

Guanosine (Standard) DL-Guanosine (Standard); Vernine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Disease markers Endocrine diseases Endogenous metabolite Source Classification	Reference Standards HSV Endogenous Metabolite
Guanosine (Standard) is the analytical standard of Guanosine. This product is intended for research and analytical applications. Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity. In Vitro: Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction, and intracellular signal transduction (cGMP).

HY-W010918R

*Adenosine 5'-diphosphate* (Standard)** Adenosine diphosphate (Standard); ADP (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder Source Classification	Reference Standards Endogenous Metabolite
Adenosine 5'-diphosphate (Standard) is the analytical standard of Adenosine 5'-diphosphate. This product is intended for research and analytical applications. Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors. In Vitro: Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.

HY-D0199R

*Adenosine 5'-diphosphate* disodium (Standard)** Adenosine diphosphate disodium (Standard); ADP disodium (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
Adenosine 5'-diphosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-diphosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-131576

Thymidine 5′-diphosphate dTDP	Infection Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Thymidine 5′-diphosphate (dTDP) is a key product for pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is generated via the phosphorylation of thymidine 5'-monophosphate (dTMP) catalyzed by thymidylate kinase (TMPK), a process requiring ATP and Mg ²⁺. Thymidine 5′-diphosphate is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels enables the assessment of TMPK activity .

HY-W008915R

*Cytidine 5'-diphosphate* trisodium salt (Standard)** CDP (Standard)	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards DNA/RNA Synthesis
Cytidine 5'-diphosphate (trisodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (trisodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2].

HY-113066AR

*Guanosine 5'-diphosphate* disodium salt (Standard)** GDP disodium salt (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Hepcidin Endogenous Metabolite Potassium Channel Reference Standards
Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-B0739AR

Citicoline sodium (Standard) Cytidine diphosphate-choline sodium (Standard); CDP-Choline sodium (Standard); Cytidine 5'-diphosphocholine sodium (Standard)	Alkaloids Structural Classification Microorganisms other families Animals Other Alkaloids Plants Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) Caspase
Citicoline sodium (Standard) is the analytical standard of Citicoline sodium. This product is intended for research and analytical applications. Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study.

HY-113400

Cytidine 5'-diphosphate Cytidine diphosphate	Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Cytidine 5'-diphosphate (Cytidine diphosphate) is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-N7740

*Adenosine 2',5'-diphosphate* sodium**	Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	P2Y Receptor Endogenous Metabolite
Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors .

HY-N11102

*Thymidine-5'-diphosphate-L-rhamnose* dTDP-L-Rhamnose	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Leguminosae Vigna radiata (L.) Wilczek Plants Endogenous metabolite Source Classification	Endogenous Metabolite Bacterial
Thymidine-5'-diphosphate-L-rhamnose (dTDP-L-Rhamnose) is a key activated nucleotide sugar in bacteria, with a K_D value of 13 μM for Listeria monocytogenes RmlT. Thymidine-5'-diphosphate-L-rhamnose acts as a high-energy donor for L-Rhamnose (HY-N1420), and is specifically used for the synthesis of bacterial cell wall polysaccharides, capsules and virulence factors .

HY-100313

YM-53601 free base	Alkaloids Carbazole Alkaloids	Farnesyl Transferase HCV
YM-53601 free base, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo . YM-53601 free base inhibits squalene synthase derived from human hepatoma cells with an IC₅₀ of 79 nM. Lipid-lowering agent . YM-53601 free base is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV propagation .

HY-135867F

*NHC-diphosphate* triammonium** 1 Publications Verification	Infection Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	CHIKV Endogenous Metabolite Enterovirus HCV Topoisomerase SARS-CoV
NHC-diphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a diphosphate form . NHC-diphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA .

HY-135867D

NHC-diphosphate 1 Publications Verification	Infection Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	CHIKV Endogenous Metabolite Enterovirus HCV Topoisomerase SARS-CoV
NHC-diphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a diphosphate form . NHC is a pyrimidine ribonucleoside and behaves as a potent anti-virus agent. NHC effectively inhibits the replication of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV) .

HY-N1717

2-Acetylbenzoic acid	Natural Products Ketones, Aldehydes, Acids Impatiens balsamina Linn. Balsaminaceae Plants Source Classification	Platelet-activating Factor Receptor (PAFR)
2-Acetylbenzoic acid, a Benzoic acid (HY-N0216) derivative, is a weak platelet aggregation inhibitor. 2-Acetylbenzoic acid inhibits Adenosine 5'-diphosphate (ADP, HY-W010918)-induced platelet aggregation .

HY-134556

2'-Hydroxyflavanone	Flavonoids Mimosa pudica Linn. Leguminosae Flavonones Plants Source Classification	Apoptosis
2'-Hydroxyflavanone is a flavanone that can inhibit cancer cell proliferation, induce apoptosis, and reduce inflammation. 2'-Hydroxyflavanone shows inhibitory effect on platelet aggregation caused by two inducers with IC₅₀s 47.8 μM arachidonic acid (AA) and 147.2 μM aenosine diphosphate (ADP) .

HY-131597

8-Oxo-GTP 8-Hydroxyguanosine triphosphate	Source Classification	Reactive Oxygen Species (ROS)
8-Oxo-GTP is an oxidized guanine nucleotide, produced by reactive oxygen species (ROS). 8-Oxo-GTP serves as a substrate for MutT protein, GTP cyclohydrolase II, Mycobacterium tuberculosis MutT1, and Mycobacterium tuberculosis Rv1700, which hydrolyze it to corresponding nucleoside monophosphates or diphosphates. 8-Oxo-GTP causes detrimental effects including mutations and mistranslation when incorporated into nucleic acids. 8-Oxo-GTP can be used for the research of cancer and tuberculosis .

HY-W008940R

*Cytidine 5'-diphosphate* disodium salt (Standard)** Cytidine diphosphate disodium (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
Cytidine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-W010832R

*Uridine-5'-diphosphate* disodium salt (Standard)**	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite
Uridine-5'-diphosphate disodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52 for human P2Y6 receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-B0739R

Citicoline (Standard) Cytidine diphosphate-choline (Standard); CDP-Choline (Standard); Cytidine 5'-diphosphocholine (Standard)	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Animals Other Alkaloids Plants Endogenous metabolite Source Classification	Reference Standards Apoptosis Endogenous Metabolite Caspase Reactive Oxygen Species (ROS)
Citicoline (Cytidine diphosphate-choline) (Standard) is the analytical standard of Citicoline. This product is intended for research and analytical applications. Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study.

HY-A0129R

Histamine phosphate (Standard) Histamine diphosphate (Standard)	Alkaloids Structural Classification Other Alkaloids Endogenous metabolite Source Classification	Reference Standards Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Histamine phosphate (Standard) is the analytical standard of Histamine phosphate (HY-A0129). This product is intended for research and analytical applications. Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine phosphate can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-N14932

Aggreceride A	Natural Products Microorganisms Source Classification	Platelet-activating Factor Receptor (PAFR)
Aggreceride A is a platelet aggregation inhibitor. Aggreceride A shows an inhibitory activity against aggregation induced by Adenosine 5'-diphosphate (ADP) (HY-W010918), Arachidonic acid (HY-109590) and PAF (platelet activating factor), but was less active against aggregation induced by collagen .

HY-N14933

Aggreceride B	Natural Products Microorganisms Source Classification	Platelet-activating Factor Receptor (PAFR)
Aggreceride B is a platelet aggregation inhibitor. Aggreceride B shows an inhibitory activity against aggregation induced by Adenosine 5'-diphosphate (ADP) (HY-W010918), Arachidonic acid (HY-109590) and PAF (platelet activating factor), but was less active against aggregation induced by collagen .

HY-N14934

Aggreceride C	Natural Products Microorganisms Source Classification	Platelet-activating Factor Receptor (PAFR)
Aggreceride C is a platelet aggregation inhibitor. Aggreceride C shows an inhibitory activity against aggregation induced by Adenosine 5'-diphosphate (ADP) (HY-W010918), Arachidonic acid (HY-109590) and PAF (platelet activating factor), but was less active against aggregation induced by collagen .

HY-124723

Gerfelin	Microorganisms Antibiotics Other Antibiotics Source Classification	Farnesyl Transferase
Gerfelin inhibits *geranylgeranyl diphosphate* synthase (GGPP synthase) activity with an IC₅₀** of 3.5 μg/mL .

Species:	Human (10)
Tag:	His (10) GST (1)
Source:	HEK293 (2) P. pastoris (1) Sf9 insect cells (1) E. coli (6)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P70224

	GGPS1 Protein, Human (His) rHuGeranylgeranyl pyrophosphate synthase/GGPS1, His; Geranylgeranyl Pyrophosphate Synthase; GGPP Synthase; GGPPSase; (2E; 6E)-Farnesyl diphosphate Synthase; Dimethylallyltranstransferase; Farnesyl diphosphate Synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate Synthase; Geranyltranstransferase; GGPS1	Human	E. coli
	The GGPS1 protein is responsible for catalyzing the trans-addition of three molecules of isopentenyl pyrophosphate (IPP) to dimethylallyl pyrophosphate (DMAPP) to synthesize geranylgeranyl pyrophosphate. This compound is an important precursor for the biosynthesis of carotenoids and geranylated proteins. GGPS1 Protein, Human (His) is the recombinant human-derived GGPS1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P702577

	GGPS1 Protein, Human (HEK293, His) rHuGeranylgeranyl pyrophosphate synthase/GGPS1, His; Geranylgeranyl Pyrophosphate Synthase; GGPP Synthase; GGPPSase; (2E; 6E)-Farnesyl diphosphate Synthase; Dimethylallyltranstransferase; Farnesyl diphosphate Synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate Synthase; Geranyltranstransferase; GGPS1	Human	HEK293
	The GGPS1 protein is responsible for catalyzing the trans-addition of three molecules of isopentenyl pyrophosphate (IPP) to dimethylallyl pyrophosphate (DMAPP) to synthesize geranylgeranyl pyrophosphate. This compound is an important precursor for the biosynthesis of carotenoids and geranylated proteins. GGPS1 Protein, Human (HEK293, His) is the recombinant human-derived GGPS1, expressed by HEK293, with C-His labeled tag. The total length of GGPS1 Protein, Human (HEK293, His) is 300 a.a..

HY-P72193

	FDFT1 Protein, Human (His) DGPT; ERG9; Farnesyl diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; FDFT_HUMAN; FDFT1; FPP:FPP farnesyltransferase; SQS; Squalene synthase; Squalene synthetase; SS	Human	E. coli
	FDFT1 is a key enzyme in cellular metabolism responsible for coordinating the condensation of two farnesyl pyrophosphate (FPP) molecules, a key step in sterol biosynthesis. The process proceeds in two distinct steps: First, two FPP molecules react to form the stable squalene diphosphate intermediate (PSQPP), releasing protons and inorganic diphosphate. FDFT1 Protein, Human (His) is the recombinant human-derived FDFT1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P74591

	RRM1 Protein, Human (sf9, His-GST) Ribonucleoside-diphosphate reductase large subunit; RRM1; RR1	Human	Sf9 insect cells
	RRM1 Protein, crucial for DNA synthesis, catalyzes the biosynthesis of deoxyribonucleotides from ribonucleotide precursors. Its enzymatic activity is essential, providing building blocks for accurate and efficient DNA replication. RRM1 Protein, Human (sf9, His-GST) is the recombinant human-derived RRM1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P70299

	NME1/NDPKA Protein, Human (His) 1 Publications Verification rHuNucleoside diphosphate kinase A/NDPKA, His; Nucleoside diphosphate Kinase A; NDK A; NDP Kinase A; Granzyme A-Activated DNase; GAAD; Metastasis Inhibition Factor nm23; Tumor Metastatic Process-Associated Protein; nm23-H1; NME1; NDPKA; NM23	Human	E. coli
	The NME1/NDPKA protein plays a crucial role in the synthesis of nucleoside triphosphates and exhibits multiple activities, including nucleoside diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease functions. NME1/NDPKA Protein, Human (His) is the recombinant human-derived NME1/NDPKA protein, expressed by E. coli , with N-6*His labeled tag.

HY-P76534

	p53R2 Protein, Human (His) Ribonucleoside-diphosphate reductase subunit M2 B; p53R2; RRM2B	Human	E. coli
	The p53R2 protein is essential for cell survival and operates in a p53/TP53-dependent manner to support DNA repair. It provides essential deoxyribonucleotides for DNA repair, particularly in G1 or G2 arrested cells, and contains an iron-tyrosyl radical center critical for catalysis. p53R2 Protein, Human (His) is the recombinant human-derived p53R2 protein, expressed by E. coli , with N-His labeled tag.

HY-P71267

	RRM2 Protein, Human (HEK293, His) Ribonucleoside-diphosphate Reductase Subunit M2; Ribonucleotide Reductase Small Chain; Ribonucleotide Reductase Small Subunit; RRM2; RR2	Human	HEK293
	RRM2 Protein, pivotal in DNA synthesis, catalyzes deoxyribonucleotide biosynthesis from ribonucleotide precursors, ensuring vital building blocks for DNA replication. Beyond nucleotide biosynthesis, RRM2 inhibits Wnt signaling, indicating involvement in regulating this crucial cellular pathway. RRM2 Protein, Human (HEK293, His) is the recombinant human-derived RRM2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71737

	GDI2 Protein, Human (P.pastoris, His) GDI-2; GDP dissociation inhibitor 2; Guanosine diphosphate dissociation inhibitor 2; Rab GDI beta; RABGDIB	Human	P. pastoris
	GDI2 protein inhibits the exchange of GDP to GTP in Rab proteins and regulates intracellular membrane transport. GDI2 Protein, Human (P.pastoris, His) is the recombinant human-derived GDI2 protein, expressed by P. pastoris , with N-His labeled tag.

HY-P70903

	IDI2 Protein, Human (His, solution) Isopentenyl-diphosphate Delta-Isomerase 2; Isopentenyl Pyrophosphate Isomerase 2; IPP Isomerase 2; IPPI2; IDI2	Human	E. coli
	IDI2 protein plays a crucial role in catalyzing the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP), leading to the formation of its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). This enzymatic activity is a key step in the biosynthetic pathway, contributing to the generation of essential building blocks for various cellular processes. IDI2 Protein, Human (His, solution) is the recombinant human-derived IDI2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70903A

	IDI2 Protein, Human (C-His) Isopentenyl-diphosphate Delta-Isomerase 2; Isopentenyl Pyrophosphate Isomerase 2; IPP Isomerase 2; IPPI2; IDI2	Human	E. coli
	IDI2 protein plays a crucial role in catalyzing the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP), leading to the formation of its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). This enzymatic activity is a key step in the biosynthetic pathway, contributing to the generation of essential building blocks for various cellular processes. IDI2 Protein, Human (C-His) is the recombinant human-derived IDI2 protein, expressed by E. coli , with C-8*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-W654288

NAD+-d4
NAD+-d₄ is the deuterium-labeled NAD+ (HY-B0445). NAD+-d₄ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

HY-W010918S2

Adenosine 5'-diphosphate-15N5 dilithium

Adenosine 5'-diphosphate- ¹⁵N₅ (Adenosine diphosphate- ¹⁵N₅ dilithium) dilithium is ¹⁵N labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-W010918S3

Adenosine 5'-diphosphate-13C5

Adenosine 5'-diphosphate- ¹³C₅ (Adenosine diphosphate- ¹³C₅) is the ¹³C-labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.

HY-113066S1

Guanosine 5'-diphosphate-13C10 dilithium

Guanosine 5'-diphosphate- ¹³C₁₀ (GDP- ¹³C₁₀) dilithium is ¹³C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-113037CS

Farnesyl pyrophosphate-d2 triammonium

Farnesyl pyrophosphate-d₂ (Farnesyl diphosphate-d₂) triammonium is a deuterium labeled Farnesyl pyrophosphate triammonium (HY-113037C). Farnesyl pyrophosphate ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.

HY-113066S

Guanosine 5'-diphosphate-15N5 dilithium

Guanosine 5'-diphosphate- ¹⁵N₅ (GDP- ¹⁵N₅) dilithium is ¹⁵N labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-113359AS2

*Uridine 5'-diphosphate-13C9,15N2 dilithium*
Uridine 5'-diphosphate- ¹³C₉, ¹⁵N₂ dilithium is ¹³C and ¹⁵N-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor.

HY-B0341S

Nicorandil-d4
Nicorandil-d₄ (SG-75-d₄) is the deuterium labeled Nicorandil. Nicorandil (SG-75) is a potent potassium channel activator and targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (KATP). Nicorandil is a nicotinamide ester with vasodilatory and cardioprotective effects and has the potential for angina and forischemic heart diseases .

HY-17589S

Chloroquine-d5 diphosphate

Chloroquine-d₅ (diphosphate) is the deuterium labeled Chloroquine (phosphate). Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC₅₀=1.13 μM) .

HY-113037AS

Farnesyl pyrophosphate-d6

Farnesyl pyrophosphate-d₆ (Farnesyl diphosphate-d₆) is a deuterium labeled Farnesyl pyrophosphate (HY-113037B). Farnesyl pyrophosphate is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.

HY-125954S

Uridine diphosphate glucuronic acid-13C,15N2

Uridine diphosphate glucuronic acid- ¹³C, ¹⁵N₂ (UDP-α-D-glucuronic acid- ¹³C, ¹⁵N₂) is the ¹³C- and ¹⁵N-labeled Uridine diphosphate glucuronic acid (HY-125954). Uridine diphosphate glucuronic acid ammonium (UDP-α-D-glucuronic acid ammonium) is a glucuronic acid donor. Uridine diphosphate glucuronic acid ammonium transfers its glucuronic acid moiety to acceptor molecules, thereby forming "ether" glucuronides, while being converted into uridine 5'-pyrophosphate. Uridine diphosphate glucuronic acid ammonium serves as a substrate for Arabidopsis UDP-GlcA 4-epimerase 1, and undergoes reversible 4-epimerization to generate UDP-α-D-galacturonic acid .

HY-B0631S

Alendronic acid-d6
Alendronic acid-d₆ is the deuterium labeled Alendronic acid. Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Paget’s disease .

HY-131606S

Cidofovir diphosphate-13C3

Cidofovir diphosphate- ¹³C₃ is the ¹³C-labeled Cidofovir diphosphate (HY-131606). Cidofovir diphosphate is the intracellular active metabolite of Cidofovir (HY-17438) and its oral prodrug Brincidofovir (HY-14532). By inhibiting viral DNA polymerase (Ki ≈ 76.3 μM), cidofovir diphosphate is widely used in studies on double-stranded DNA virus infections, including cytomegalovirus (CMV), adenovirus (AdV), and poxviruses (such as monkeypox and molluscum contagiosum virus, MCV) .

HY-B0739AS

Citicoline-d9 sodium

Citicoline-d₉ (Cytidine diphosphate-choline-d₉) sodium is the deuterium labeled Citicoline sodium (HY-B0739A). Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study .

HY-15592AS

Cabotegravir-d3 sodium
Cabotegravir-d₃ (sodium) is the deuterium labeled Cabotegravir sodium. Cabotegravir sodium is a highly potent HIV integrase inhibitor with an IC50 value of 2.5 nM for HIVADA. Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltr

HY-113400S3

*Cytidine diphosphate-d13 dilithium*
Cytidine diphosphate-d₁₃ dilithium is deuterium labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-113400S

*Cytidine diphosphate-15N3 dilithium*
Cytidine diphosphate- ¹⁵N₃ dilithium is ¹⁵N labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-12651S

Primaquine-d3 diphosphate
Primaquine-d₃ (diphosphate) is the deuterium labeled Primaquine diphosphate. Primaquine Diphosphate (Primaquine phosphate), an 8-aminoquinoline, exerts a broad spectrum of activities against various stages of parasitic malaria. Primaquine Diphosphate remains as the only agent that destroys late hepatic stages and latent tissue forms of Plasmodium vivax and Plasmodium ovale .

HY-113400S1

*Cytidine diphosphate-13C9 dilithium*
Cytidine diphosphate- ¹³C₉ dilithium is ¹³C-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-113066S2

Guanosine 5'-diphosphate-d13 dilithium

Guanosine 5'-diphosphate-d₁₃ (GDP-d₁₃) dilithium is deuterium labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-113359AS

*Uridine 5'-diphosphate-d12 dilithium*
Uridine 5'-diphosphate-d₁₂ (UDP-d12) dilithium is the deuterium labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor .

HY-113400S2

*Cytidine diphosphate-13C9,15N3 dilithium*
Cytidine diphosphate- ¹³C₉, ¹⁵N₃ dilithium is ¹³C and ¹⁵N-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-113359AS3

*Uridine 5'-diphosphate-15N2 dilithium*
Uridine 5'-diphosphate- ¹⁵N₂ dilithium is ¹⁵N labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor.

HY-113359AS1

*Uridine 5'-diphosphate-13C9 dilithium*
Uridine 5'-diphosphate- ¹³C₉ (UDP-13C9 ) dilithium is ¹³C-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor .

HY-113066S3

Guanosine 5'-diphosphate-13C10,15N5 dilithium

Guanosine 5'-diphosphate- ¹³C₁₀, ¹⁵N₅ (GDP- ¹³C₁₀, ¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-W013724S

Inosine-5'-diphosphate-15N4 dilithium

Inosine-5'-diphosphate- ¹⁵N₄ dilithium (IDP- ¹⁵N₄ dilithium) is ¹⁵N labeled Inosine-5'-diphosphate dilithium. Inosine-5'-diphosphate (IDP) is a decoy substrate of NM23-H2. Inosine-5'-diphosphate has a superior bond capacity on GDP-binding pocket of NM23-H2 (K_D: 5.0 μM). Inosine-5'-diphosphate abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research .

HY-11101S

Alendronate-d6 sodium hydrate
Alendronate-d₆ sodium hydrate is deuterated labeled Alendronate sodium hydrate (HY-11101). Alendronate sodium hydrate is a farnesyl diphosphate synthase inhibitor with IC₅₀ of 460 nM.

HY-135811S

Desethyl chloroquine-d4
Desethyl chloroquine-d₄ is the deuterium labeled Desethyl chloroquine. Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity .

HY-135811S1

Desethyl chloroquine-d5
Desethyl chloroquine-d₅ is deuterium labeled Desethyl chloroquine. Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity .

HY-B1826S2

Adefovir-d4
Adefovir-d₄ is the deuterium labeled Adefovir. Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC₅₀ of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses .

HY-107867S1

(Rac)-Clopidogrel hydrogen-d9 sulfate

(Rac)-Clopidogrel hydrogen-d₉ sulfate is the deuterium labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects .

HY-107867S2

Clopidogrel-13C,d3 sulfate

Clopidogrel- ¹³C,d₃ sulfate is the deuterium and ¹³C-labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects .

HY-15283AS1

(±)-Clopidogrel-d4

(±)-Clopidogrel-d₄ ((±)-Clopidogrelum-d₄) is the deuterium labeled (±)-Clopidogrel (HY-107867). (±)-Clopidogrel is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel has anti-inflammatory effects .

HY-15592S4

Cabotegravir-d6

Cabotegravir-d₆ (GSK-1265744-d₆) is the deuterium labeled Cabotegravir (HY-15592). Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC₅₀ values of 2.5 nM, 0.41 μM and 0.81 μM for HIV_ADA, OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS .

Host:	Mouse (2) Rabbit (8)
Reactivity:	Human (10) Rat (5) Mouse (3)
Application:	IHC-P (5) ICC/IF (4) IF-Tissue (1) IP (2) IHC-F (3) WB (10) FC (2)
Isotype:	IgG (8) IgG1 (1) IgG2a (1)
Conjugation:	Non-conjugated (10)
Clonality:	Monoclonal (7) Recombinant (5)
Modification:	Unmodified (7)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82976

	DPS1 Antibody (YA2721) Trans-prenyltransferase 1; TPT 1; Solanesyl-diphosphate synthase subunit 1; Decaprenyl-diphosphate synthase subunit 1	WB, IP	Human
	DPS1 Antibody (YA2721) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DPS1.

HY-P82976A

	DPS1 Antibody (YA2721)(PBS only) Trans-prenyltransferase 1; TPT 1; Solanesyl-diphosphate synthase subunit 1; Decaprenyl-diphosphate synthase subunit 1	WB, IP	Human
	DPS1 Antibody (YA2721) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DPS1.

HY-P86994

	NUDT5 Antibody (YA6687) ADP sugar pyrophosphatase antibody; ADP-sugar pyrophosphatase antibody; hYSAH 1 antibody; hYSAH1 antibody; Nucleoside diphosphate linked moiety X motif 5 antibody; Nucleoside diphosphate linked moiety X type motif 5 antibody; Nucleoside diphosphate-linked moiety X motif 5 antibody; Nudix (nucleoside diphosphate linked moiety X) type motif 5 antibody; Nudix motif 5 antibody; Nudix type motif 5 antibody; ADP sugar pyrophosphatase antibody; ADP-sugar pyrophosphatase antibody; hYSAH 1 antibody; hYSAH1 antibody; Nucleoside diphosphate linked moiety X motif 5 antibody; Nucleoside diphosphate linked moiety X type motif 5 antibody; Nucleoside diphosphate-linked moiety X motif 5 antibody; Nudix (nucleoside diphosphate linked moiety X) type motif 5 antibody; Nudix motif 5 antibody; Nudix type motif 5 antibody; NUDT 5 antibody; Nudt5 antibody; NUDT5_HUMAN antibody; YSA1 antibody; YSA1H antibody;	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	NUDT5 Antibody (YA6687) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NUDT5.

HY-P81705

	NUDT19 Antibody (YA1450) nudix (nucleoside diphosphate linked moiety X)-type motif 19; RP2	WB, IHC-F, IHC-P, ICC/IF	Human, Rat
	NUDT19 Antibody (YA1450) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NUDT19.

HY-P81705A

	NUDT19 Antibody (YA1450)(PBS only) nudix (nucleoside diphosphate linked moiety X)-type motif 19; RP2	WB, IHC-F, IHC-P, ICC/IF	Human, Rat
	NUDT19 Antibody (YA1450) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NUDT19.

HY-P83223

	NME2 Antibody (YA2968) NME2; NM23B; Nucleoside diphosphate kinase B; NDK B; NDP kinase B; C-myc purine-binding transcription factor PUF; Histidine protein kinase NDKB; nm23-H2	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	NME2 Antibody (YA2968) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NME2.

HY-P81289

	NM23A Antibody (YA1002) NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1	WB	Human, Mouse, Rat
	NM23A Antibody (YA1002) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NM23A.

HY-P81289A

	NM23A Antibody (YA1003) NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1	WB	Human
	NM23A Antibody (YA1003) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NM23A.

HY-P85299

	NM23A Antibody (YA4991) NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1	WB, IHC-P, IHC-F, IF-Tissue	Human
	NM23A Antibody (YA4991) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to NM23A.

HY-P81289AA

	NM23A Antibody (YA1003)(PBS only) NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1	WB	Human
	NM23A Antibody (YA1003) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NM23A.

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Cat. No.	Product Name		Classification

HY-163785

1"-α-Azido-RDPr		Azide
1"-α-Azido-RDPr (Compound 11) is an analog of adenosine diphosphate ribose, and exhibits inhibitory efficacy against the SARS-CoV-2 nonstructural protein macodomain SARS-CoV-2 NSP3 Mac1 with an IC₅₀ of 30 nM .

Cat. No.	Product Name		Classification

HY-W010918

Adenosine 5'-diphosphate Maximum Cited Publications 9 Publications Verification Adenosine diphosphate; ADP		Nucleotide Analogs Adenine Nucleotide
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-113066A

*Guanosine 5'-diphosphate* disodium salt** 2 Publications Verification GDP disodium salt		Nucleotide Analogs
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-D0199

*Adenosine 5'-diphosphate* disodium** Maximum Cited Publications 9 Publications Verification Adenosine diphosphate disodium; ADP disodium		Nucleotide Analogs Adenine Nucleotide
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-W010791

*Adenosine 5'-diphosphate* sodium salt** Maximum Cited Publications 9 Publications Verification		Nucleotide Analogs Adenine Nucleotide
Adenosine 5'-diphosphate sodium salt is a nucleoside diphosphate and the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase through its action on P_2T-purinergic receptors .

HY-113066

Guanosine 5'-diphosphate GDP		Nucleotide Analogs
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate can be used in the research of AI .

HY-W008915

*Cytidine 5'-diphosphate* trisodium salt** CDP		Nucleotide Analogs
Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA .

HY-137243

*Adenosine 3',5'-diphosphate* disodium**		Nucleotide Analogs Adenine Nucleotide
Adenosine 3',5'-diphosphate disodium is an endogenous purine nucleotide. Adenosine 3',5'-diphosphate disodium acts as an inhibitor of bovine adrenal estrogen sulfotransferase (EST) with a K_i value of 7.0 μM. It also serves as an indispensable specific cofactor for the pregnenolone-binding protein (PBP) steroid-binding complex, with an EC₅₀ value of 1.5 μM in guinea pigs .

HY-W010861

*2'-Deoxycytidine-5'-diphosphate* trisodium** 1 Publications Verification dCDP trisodium		Nucleotide Analogs Cytidine Nucleotide
2'-Deoxycytidine-5'-diphosphate (dCDP) trisodium is an endogenous metabolite.

HY-W010854

2'-Deoxyadenosine 5'-di-phos-phate disodium dADP disodium		Nucleotide Analogs Adenine Nucleotide
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .

HY-154828

Uridine 3′,5′-diphosphate 3′,5′-UDP		Nucleotide Analogs Uracil Nucleotide
Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) is a competitive RNase inhibitor .

HY-113400

Cytidine 5'-diphosphate Cytidine diphosphate		Nucleotide Analogs
Cytidine 5'-diphosphate (Cytidine diphosphate) is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-W749117

*Inosine 5′-diphosphate* sodium**		Nucleotide Analogs Inosine Nucleoside
Inosine 5’-diphosphate sodium is a purine ribonucleoside 5’-diphosphate with inosine as the nucleobase, which can participate in intracellular energy metabolism and signal transduction processes .

HY-W008940

*Cytidine 5'-diphosphate* disodium salt** Cytidine diphosphate disodium		Nucleotide Analogs Cytidine Nucleotide
Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-D0882

*Adenosine 5'-diphosphate* dicyclohexylammonium**		Nucleotide Analogs Adenine Nucleotide
Adenosine 5'-diphosphate dicyclohexylammonium is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate dicyclohexylammonium induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors .

HY-177787A

2'-Deoxy-N-methyl-AMP ammonium		Nucleotide Analogs
2'-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative and a glycosyl donor. On one hand, 2'-Deoxy-N-methyl-AMP ammonium acts as a specific substrate for N6-methyl-AMP aminohydrolase, and it is catalytically converted to dIMP to participate in the nucleotide metabolic cycle. On the other hand, 2'-Deoxy-N-methyl-AMP ammonium also serves as a guanosine diphosphate (GDP)-linked fucose derivative donor, driving site-specific glycoconjugation of proteins under the mediation of α-1,3-fucosyltransferase. 2'-Deoxy-N-methyl-AMP ammonium is an important molecular tool for investigating the mechanisms of nucleotide modification and protein glycosylation .

HY-138227

3′-Deoxyadenosine 5′-diphosphate 3′-dADP		Nucleotide Analogs Adenine Nucleotide
3′-Deoxyadenosine 5′-diphosphate (3′-dADP)It can be used to study various physiological processes such as energy metabolism and information transmission.

HY-138227A

*3′-Deoxyadenosine 5′-diphosphate* disodium** 3′-dADP disodium		Nucleotide Analogs Adenine Nucleotide
3′-Deoxyadenosine 5′-diphosphate (3′-dADP) disodiumIt can be used to study various physiological processes such as energy metabolism and information transmission.

HY-131576B

*Thymidine 5′-diphosphate* disodium** dTDP disodium		Nucleoside Analogs Nucleotide Analogs
Thymidine 5′-diphosphate (dTDP) disodium is a key product for pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is generated via the phosphorylation of thymidine 5'-monophosphate (dTMP) catalyzed by thymidylate kinase (TMPK), a process requiring ATP and Mg ²⁺. Thymidine 5′-diphosphate disodium is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels enables the assessment of TMPK activity .

HY-W749893

dGDP sodium 2'-Deoxyguanosine-5'-diphosphate sodium		Nucleoside Analogs Nucleotide Analogs
dGDP (2'-Deoxyguanosine-5'-diphosphate) sodium is a monomeric raw material that can be used for nucleic acid synthesis.

HY-172507

3'-O-Methylguanosine-5'-diphosphate		Nucleotide Analogs Guanine Nucleotide
3'-O-Methylguanosine-5'-diphosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W393450A

dCDP disodium 2'-Deoxycytidine-5'-diphosphate disodium		Nucleoside Analogs Nucleotide Analogs
dCDP (2'-Deoxycytidine-5'-diphosphate) disodium is a monomeric raw material that can be used for nucleic acid synthesis.

HY-164112

*1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium* 18:1 CDP DG		Nucleotide Analogs Cytidine Nucleotide
1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium (18:1 CDP DG) is a diacylglycerol derivate .

Targets Recommended: Potassium Channel UGT Na+/K+ ATPase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0445GL

NAD+ (GMP Like) β-DPN (GMP Like); β-NAD (GMP Like); β-Nicotinamide Adenine Dinucleotide (GMP Like)	Endogenous Metabolite	Metabolic Disease
NAD+ (GMP Like) is NAD+ (HY-B0445) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

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Potassium diphosphate

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