Oxythiamine diphosphate
Based on 1 publication(s) in Google Scholar
Oxythiamin diphosphate is a potent transketolase (TK) inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 10497-04-8
- Formula: C12H17N3O8P2S
- Molecular Weight:425.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Oxythiamine diphosphate
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Biological Activity
Ki: 30 nM (thiamine pyrophosphate)[1].
Rat liver TK is inhibited at 50% by oxythiamine diphosphate in concentrations of 0.02–0.2 μM. I50 value of Oxythiamine diphosphate for yeast transketolase is approximately 0.03 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 10497-04-8
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Molecular Weight 425.29
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Formula C12H17N3O8P2S
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SMILES
CC1=C(CCOP(OP(O)(O)=O)([O-])=O)SC=[N+]1CC2=CN=C(C)NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Chem Biol
Pharmacological perturbation of thiamine metabolism sensitizes Pseudomonas aeruginosa to multiple antibacterial agents. [Abstract]2022 Aug 18;29(8):1317-1324.e5. PMID: 35901793
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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