2. Metabolic Enzyme/Protease
  3. Transketolase
  4. Oxythiamine diphosphate

Oxythiamin diphosphate is a potent transketolase (TK) inhibitor.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Oxythiamine diphosphate ammonium) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Oxythiamine diphosphate Chemical Structure

Oxythiamine diphosphate Chemical Structure

CAS No. : 10497-04-8

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Oxythiamine diphosphate Related Antibodies

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Description

Oxythiamin diphosphate is a potent transketolase (TK) inhibitor[1].

IC50 & Target

Ki: 30 nM (thiamine pyrophosphate)[1].
In Vitro

Rat liver TK is inhibited at 50% by oxythiamine diphosphate in concentrations of 0.02–0.2 μM. I50 value of Oxythiamine diphosphate for yeast transketolase is approximately 0.03 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Oxythiamine diphosphate Related Antibodies
Molecular Weight

425.29

Formula

C12H17N3O8P2S
CAS No.
SMILES

CC1=C(CCOP(OP(O)(O)=O)([O-])=O)SC=[N+]1CC2=CN=C(C)NC2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Oxythiamine diphosphate Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oxythiamine diphosphate10497-04-8TransketolaseInhibitorinhibitorinhibit

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