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Cat. No.: HY-112889B

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Oxythiamine diphosphate ammonium

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

Oxythiamin diphosphate ammonium is a potent transketolase (TK) inhibitor.

For research use only. We do not sell to patients.

Purity: 98.42%

Storage:

-20°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Oxythiamine diphosphate ammonium Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Publications (1)
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Oxythiamin diphosphate ammonium is a potent transketolase (TK) inhibitor^[1].

In Vitro

Rat liver TK was inhibited at 50% by oxythiamine diphosphate ammonium in concentrations of 0.02-0.2 μM. I₅₀ value of Oxythiamine diphosphate ammonium for yeast transketolase is approximately 0.03 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Appearance Solid
Color White to light yellow
SMILES

CC1=C(CCOP(OP(O)(O)=O)([O-])=O)SC=[N+]1CC2=CN=C(C)NC2=O.N.[x]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Publications (1)

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Cell Chem Biol

Pharmacological perturbation of thiamine metabolism sensitizes Pseudomonas aeruginosa to multiple antibacterial agents. [Abstract]

2022 Aug 18;29(8):1317-1324.e5. PMID: 35901793

Solvent & Solubility

In Vitro:

H₂O : 12.5 mg/mL (Need ultrasonic)

View the Complete Stock Solution Preparation Table

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tylicki A, et al. Thiamine and selected thiamine antivitamins - biological activity and methods of synthesis. Biosci Rep. 2018;38(1):BSR20171148. Published 2018 Jan 10. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Oxythiamine diphosphate ammonium

1 Cited Publications

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Biological Activity
- Description
- In Vitro
Chemical Information
Publications (1)
Solvent & Solubility
- In Vitro
Purity & Documentation
References

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Oxythiamine diphosphate ammonium

Publications Citing Use of MedChemExpress (MCE) Oxythiamine diphosphate ammonium

Biological Activity

Chemical Information

Publications (1)

Solvent & Solubility

Purity & Documentation

References

Calculators

Help & FAQs

Oxythiamine diphosphate ammonium Related Classifications

HY-112889B Related Classifications