1. Metabolic Enzyme/Protease
  2. Transketolase
  3. Oxythiamine diphosphate ammonium

Oxythiamin diphosphate ammonium is a potent transketolase (TK) inhibitor.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Oxythiamine diphosphate) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Oxythiamine diphosphate ammonium Chemical Structure

Oxythiamine diphosphate ammonium Chemical Structure

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Other Forms of Oxythiamine diphosphate ammonium:

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Description

Oxythiamin diphosphate ammonium is a potent transketolase (TK) inhibitor[1].

In Vitro

Rat liver TK was inhibited at 50% by oxythiamine diphosphate ammonium in concentrations of 0.02-0.2 μM. I50 value of Oxythiamine diphosphate ammonium for yeast transketolase is approximately 0.03 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Color

White to off-white

SMILES

CC1=C(CCOP(OP(O)(O)=O)([O-])=O)SC=[N+]1CC2=CN=C(C)NC2=O.N.[x]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 12.5 mg/mL (Need ultrasonic)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Oxythiamine diphosphate ammonium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Oxythiamine diphosphate ammonium
Cat. No.:
HY-112889B
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