Thymidine 5′-diphosphate disodium
Thymidine 5′-diphosphate (dTDP) disodium is a key product for pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is generated via the phosphorylation of thymidine 5'-monophosphate (dTMP) catalyzed by thymidylate kinase (TMPK), a process requiring ATP and Mg2+. Thymidine 5′-diphosphate disodium is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels enables the assessment of TMPK activity.
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- CAS. Nr.: 28120-41-4
- Formel: C10H14N2Na2O11P2
- Molecular Weight:446.15
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
In Vitro
Thymidine 5′-diphosphate is produced by thymidylate kinase (TMPK)-catalyzed phosphorylation of thymidine 5'-monophosphate (dTMP), a process requiring ATP and Mg2+, and is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels allows the measurement of TMPK activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 28120-41-4
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Molecular Weight 446.15
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Formel C10H14N2Na2O11P2
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SMILES
O[C@H]1C[C@H](N(C=C(C(N2)=O)C)C2=O)O[C@@H]1COP(OP(O[Na])(O[Na])=O)(O)=O
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Synonyms
dTDP disodium
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)