28120-41-4
Chemical Structure
Thymidine 5′-diphosphate disodium
Synonym(s): dTDP disodium
- CAS No.: 28120-41-4
- Formula:C10H14N2Na2O11P2
- Molecular Weight:446.15
InChIKey: YFUBCYKGSJTXQX-ZJWYQBPBSA-L
SMILES: O[C@H]1C[C@H](N(C=C(C(N2)=O)C)C2=O)O[C@@H]1COP(OP(O[Na])(O[Na])=O)(O)=O
Biological Activity: Thymidine 5′-diphosphate (dTDP) disodium is a key product for pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is generated via the phosphorylation of thymidine 5'-monophosphate (dTMP) catalyzed by thymidylate kinase (TMPK), a process requiring ATP and Mg2+. Thymidine 5′-diphosphate disodium is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels enables the assessment of TMPK activity[1].
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Thymidine 5′-diphosphate disodium | Thymidine 5′-diphosphate (dTDP) disodium is a key product for pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is generated via the phosphorylation of thymidine 5'-monophosphate (dTMP) catalyzed by thymidylate kinase (TMPK), a process requiring ATP and Mg2+. Thymidine 5′-diphosphate disodium is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels enables the assessment of TMPK activity. | |||||||||||||||||||||
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Keywords
