MurB-IN-1
MurB-IN-1 is an inhibitor of Pseudomonas aeruginosa UDP-N-acetylmuramic acid enolpyruvyl reductase (MurB) with a Kd value of 3.57 μM. MurB-IN-1 is applicable to the research of Pseudomonas aeruginosa infections (cystic fibrosis-associated).
For research use only. We do not sell to patients.
- CAS No.: 2883232-46-8
- Formula: C12H7Cl2F3N2O2
- Molecular Weight:339.10
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MurB-IN-1 (Compound 44) binds potently to purified Pseudomonas aeruginosa MurB enzyme with a Kd of 3.57 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2883232-46-8
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Molecular Weight 339.10
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Formula C12H7Cl2F3N2O2
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SMILES
CC1=CC(Cl)=C(C=C1N2N=CC(C(O)=O)=C2C(F)(F)F)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Acebrón-García-de-Eulate M, et, al. Discovery of Novel Inhibitors of Uridine Diphosphate- N-Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients. J Med Chem. 2022 Feb 10;65(3):2149-2173. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MurB-IN-1 Related Classifications
HY-144071 Related Classifications
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