Ciprostene calcium
Ciprostene calcium is a prostacyclin analogue.Ciprostene calcium inhibits adenosine diphosphate-induced platelet aggregation. Ciprostene calcium can be used for research of peripheral vascular disease.
For research use only. We do not sell to patients.
- CAS No.: 81703-55-1
- Formula: C22H35CaO4+
- Molecular Weight:383.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Chemical Information
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CAS No. 81703-55-1
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Molecular Weight 383.56
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Formula C22H35CaO4+
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SMILES
C[C@@]12[C@@](C/C(C2)=C/CCCC([O-])=O)([H])[C@H]([C@@H](C1)O)/C=C/[C@@H](O)CCCCC.[Ca+2]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Cardiovascular Diseases
Cardiovascular disease can be modeled as maladaptive cardiac remodeling, where ischemic injury or pressure overload activates inflammatory signaling, fibroblast activation, extracellular-matrix deposition, cardiomyocyte hypertrophy, vascular remodeling, and progressive ventricular dysfunction. The TGF-β/SMAD axis is a central profibrotic pathway after myocardial injury and pressure overload, while innate immune and cytokine pathways regulate leukocyte recruitment, scar formation, and adverse remodeling. Key unresolved questions include which inflammatory signals are reparative versus harmful, when fibrosis is protective versus maladaptive, and whether pathway inhibition improves function without weakening necessary infarct healing or compensatory remodeling.
Purity & Documentation
References
[1]. Jones DA, et al. Activation of thromboxane and prostacyclin receptors elicits opposing effects on vascular smooth muscle cell growth and mitogen-activated protein kinase signaling cascades. Mol Pharmacol. 1995 Nov;48(5):890-6 [Content Brief]
[2]. Wolf DL, et al. Continuous intravenous dosing with ciprostene using a portable pump in ambulatory patients. J Clin Pharmacol. 1993 Feb;33(2):150-3. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ciprostene calcium Related Classifications
HY-122499 Related Classifications
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