2'-Deoxy-N-methyl-AMP ammonium
Based on 1 Customer Validation
2'-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative and a glycosyl donor. On one hand, 2'-Deoxy-N-methyl-AMP ammonium acts as a specific substrate for N6-methyl-AMP aminohydrolase, and it is catalytically converted to dIMP to participate in the nucleotide metabolic cycle. On the other hand, 2'-Deoxy-N-methyl-AMP ammonium also serves as a guanosine diphosphate (GDP)-linked fucose derivative donor, driving site-specific glycoconjugation of proteins under the mediation of α-1,3-fucosyltransferase. 2'-Deoxy-N-methyl-AMP ammonium is an important molecular tool for investigating the mechanisms of nucleotide modification and protein glycosylation.
For research use only. We do not sell to patients.
- Formula: C11H19N6O6P
- Molecular Weight:362.28
-
Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
2'-Deoxy-N-methyl-AMP ammonium (Optimized time intervals for conversion; 37 °C) is efficiently converted to dIMP by purified rat liver N6-methyl-AMP aminohydrolase, with a Km of 0.9 ± 0.2 μmol/L, Vmax of 253.7 ± 10.1 nmol min-1 mg-1, and Vmax/Km ratio of 281.9 × 103 L min-1 mg-1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Appearance Solid
-
Molecular Weight 362.28
-
Formula C11H19N6O6P
-
SMILES
O[C@H]1C[C@H](N(C=N2)C3=C2C(NC)=NC=N3)O[C@@H]1COP(O)(O)=O.N
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2'-Deoxy-N-methyl-AMP ammonium Related Classifications
HY-177787A Related Classifications
Powered by Bioz