7-Methylguanosine 5'-diphosphate sodium
Based on 1 Customer Validation
7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues.
For research use only. We do not sell to patients.
- Purity: 97.1%
- CAS No.: 104809-16-7
- Formula: C11H16N5NaO11P2
- Molecular Weight:479.21
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
7-Methylguanosine 5'-diphosphate sodium inhibits binding of eukaryotic initiation factors to reovirus capped mRNA and complex formation involving uncapped mRNA or 18 S rRNA[1].
T. brucei mRNA decapping enzyme (TbDcp2) that cleaves 7-Methylguanosine 5'-diphosphate sodium from capped RNA to generate pRNA, a substrate for TbCe1[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 104809-16-7
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Appearance Solid
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Molecular Weight 479.21
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Formula C11H16N5NaO11P2
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Color White to off-white
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SMILES
O[C@H]1[C@@H](O)[C@H](N2C(NC(N)=NC3=O)=C3[N+](C)=C2)O[C@@H]1COP([O-])(OP(O)(O[Na])=O)=O
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Synonyms
7-Methyl-GDP sodium; m7GDP sodium
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 50 mg/mL (104.34 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.0868 mL | 10.4338 mL | 20.8677 mL | 52.1692 mL |
| 5 mM | 0.4174 mL | 2.0868 mL | 4.1735 mL | 10.4338 mL | |
| 10 mM | 0.2087 mL | 1.0434 mL | 2.0868 mL | 5.2169 mL | |
| 15 mM | 0.1391 mL | 0.6956 mL | 1.3912 mL | 3.4779 mL | |
| 20 mM | 0.1043 mL | 0.5217 mL | 1.0434 mL | 2.6085 mL | |
| 25 mM | 0.0835 mL | 0.4174 mL | 0.8347 mL | 2.0868 mL | |
| 30 mM | 0.0696 mL | 0.3478 mL | 0.6956 mL | 1.7390 mL | |
| 40 mM | 0.0522 mL | 0.2608 mL | 0.5217 mL | 1.3042 mL | |
| 50 mM | 0.0417 mL | 0.2087 mL | 0.4174 mL | 1.0434 mL | |
| 60 mM | 0.0348 mL | 0.1739 mL | 0.3478 mL | 0.8695 mL | |
| 80 mM | 0.0261 mL | 0.1304 mL | 0.2608 mL | 0.6521 mL | |
| 100 mM | 0.0209 mL | 0.1043 mL | 0.2087 mL | 0.5217 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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