2. Immunology/Inflammation
  3. CD73
  4. MethADP triammonium

MethADP triammonium  (Synonyms: Adenosine 5'-(α,β-methylene)diphosphate triammonium)

Cat. No.: HY-112502C Purity: 99.03%
COA Handling Instructions

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MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor. MethADP can be used for the research of ATP-adenosine pathway.

For research use only. We do not sell to patients.

MethADP triammonium Chemical Structure

MethADP triammonium Chemical Structure

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5 mg USD 150 In-stock
10 mg USD 240 In-stock
25 mg USD 490 In-stock
50 mg USD 780 In-stock
100 mg USD 1250 In-stock
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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of MethADP triammonium:

MethADP triammonium Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor. MethADP can be used for the research of ATP-adenosine pathway[1].

In Vitro

MethADP (20 and 100 μmol/L) inhibits 5’-AMP induced adenosine formation in A498 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MethADP triammonium Related Antibodies
Molecular Weight

476.32

Formula

C11H26N8O9P2
Appearance

Solid

Color

Off-white to light yellow

SMILES

O[C@@H]1[C@H](O)[C@@H](COP(O)(CP(O)(O)=O)=O)O[C@H]1N2C=NC3=C2N=CN=C3N.N.N.N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 46.67 mg/mL (97.98 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0994 mL 10.4971 mL 20.9943 mL
5 mM 0.4199 mL 2.0994 mL 4.1989 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.0994 mL 10.4971 mL 20.9943 mL 52.4857 mL
5 mM 0.4199 mL 2.0994 mL 4.1989 mL 10.4971 mL
10 mM 0.2099 mL 1.0497 mL 2.0994 mL 5.2486 mL
15 mM 0.1400 mL 0.6998 mL 1.3996 mL 3.4990 mL
20 mM 0.1050 mL 0.5249 mL 1.0497 mL 2.6243 mL
25 mM 0.0840 mL 0.4199 mL 0.8398 mL 2.0994 mL
30 mM 0.0700 mL 0.3499 mL 0.6998 mL 1.7495 mL
40 mM 0.0525 mL 0.2624 mL 0.5249 mL 1.3121 mL
50 mM 0.0420 mL 0.2099 mL 0.4199 mL 1.0497 mL
60 mM 0.0350 mL 0.1750 mL 0.3499 mL 0.8748 mL
80 mM 0.0262 mL 0.1312 mL 0.2624 mL 0.6561 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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MethADP triammonium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MethADP triammoniumAdenosine 5'-(α,β-methylene)diphosphate triammoniumCD73ecto-5′-nucleotidase, NT5EATP5’-AMPadenosineA498Inhibitorinhibitorinhibit

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