MethADP triammonium (Synonyms: Adenosine 5'-(α,β-methylene)diphosphate triammonium)

Cat. No.: HY-112502C Purity: 99.03%: FAQs
Data Sheet SDS COA Handling Instructions

MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor. MethADP can be used for the research of ATP-adenosine pathway.

For research use only. We do not sell to patients.

MethADP triammonium Chemical Structure

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5 mg		Check price and availability
10 mg		Check price and availability
25 mg		Check price and availability
50 mg		Check price and availability
100 mg		Check price and availability

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Other Forms of MethADP triammonium:

MethADP Get quote
MethADP sodium salt Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor. MethADP can be used for the research of ATP-adenosine pathway^[1].

In Vitro

MethADP (20 and 100 μmol/L) inhibits 5’-AMP induced adenosine formation in A498 cells^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

476.32

Appearance

Solid

Formula

C₁₁H₂₆N₈O₉P₂

SMILES

O[[email protected]@H]1[[email protected]](O)[[email protected]@H](COP(O)(CP(O)(O)=O)=O)O[[email protected]]1N2C=NC3=C2N=CN=C3N.N.N.N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 46.67 mg/mL (97.98 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0994 mL	10.4971 mL	20.9943 mL
5 mM	0.4199 mL	2.0994 mL	4.1989 mL
10 mM	0.2099 mL	1.0497 mL	2.0994 mL

*Please refer to the solubility information to select the appropriate solvent.

Purity & Documentation

Purity: 99.03%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (252 KB) HNMR (301 KB) CNMR (244 KB) RP-HPLC (247 KB) MS (189 KB)

Handling Instructions (2659 KB)

References

[1]. Mohlin C, et al. Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells. Pharmacology. 2009;84(4):196-202. [Content Brief]

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords:

MethADP triammoniumAdenosine 5'-(α,β-methylene)diphosphate triammoniumCD73ecto-5′-nucleotidase, NT5EATP5’-AMPadenosineA498Inhibitorinhibitorinhibit

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