1. GPCR/G Protein
  2. Adenosine Receptor

MethADP (Synonyms: Adenosine 5'-(α,β-methylene)diphosphate)

Cat. No.: HY-112502
Handling Instructions

MethADP is a specific CD73 inhibitor.

For research use only. We do not sell to patients.

MethADP Chemical Structure

MethADP Chemical Structure

CAS No. : 3768-14-7

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

MethADP is a specific CD73 inhibitor.

IC50 & Target

CD73[1].

In Vitro

MethADP (AMP-CP: 20 μM) causes a marked inhibition of adenosine formation (0.96±0.96 μM) compared to untreated controls (9.6±1.5 μM) in A498 and RT4 cells, and MethADP (100 μM) completely inhibits the adenosine formation[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3517 mL 11.7583 mL 23.5167 mL
5 mM 0.4703 mL 2.3517 mL 4.7033 mL
10 mM 0.2352 mL 1.1758 mL 2.3517 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

425.23

Formula

C₁₁H₁₇N₅O₉P₂

CAS No.

3768-14-7

SMILES

O[[email protected]@H]([[email protected]]([[email protected]](N1C=NC2=C(N=CN=C21)N)O3)O)[[email protected]]3COP(O)(CP(O)(O)=O)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
MethADP
Cat. No.:
HY-112502
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MethADP

Cat. No.: HY-112502