2-MeSADP (Synonyms: 2-Methylthioadenosine diphosphate; 2-Methylthio-ADP)

Cat. No.: HY-108648A: Data Sheet Handling Instructions
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2-MeSADP is a P2Y receptor agonist, with an EC₅₀ of 5 nM for human P2Y12, EC₅₀ values of 19 nM and 13 nM for human P2Y13, and an EC₅₀ of 6.2 nM for mouse P2Y13. It shows slightly higher selectivity for P2Y12 over human P2Y13. 2-MeSADP triggers increases in intracellular calcium levels, Gi-mediated cAMP inhibition, adenylate cyclase inhibition and downstream signal transduction. 2-MeSADP can be used in research related to glaucoma.

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2-MeSADP Chemical Structure

CAS No. : 34983-48-7

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Other In-stock Forms of 2-MeSADP:

2-MeS-ADP trisodium

Other Forms of 2-MeSADP:

2-MeS-ADP trisodium In-stock

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P2Y1 Receptor P2Y2 Receptor P2Y6 Receptor P2Y11 Receptor P2Y12 Receptor P2Y13 Receptor P2Y14 Receptor

Biological Activity
Purity & Documentation
References
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Description

IC₅₀ & Target

P2Y13 Receptor

19 nM (EC₅₀)

P2Y12 Receptor

5 nM (EC₅₀)

Cellular Effect

Cell Line	Type	Value	Description	References
COS-7	EC₅₀	1.27 nM Compound: 2-MeSADP	Effective concentration required for the activation of wild-type P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of wild-type P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	1.58 nM Compound: 2-MeSADP	Effective concentration required for the activation of human S317A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human S317A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	100 nM Compound: 2-MeSADP	Effective concentration required for the activation of human H277A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human H277A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	11.2 nM Compound: 2-MeSADP	Effective concentration required for the activation of human T222A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human T222A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	11.7 nM Compound: 2-MeSADP	Effective concentration required for the activation of human S314T mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human S314T mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	12.6 nM Compound: 2-MeSADP	Effective concentration required for the activation of human Y136A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human Y136A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	145 nM Compound: 2-MeSADP	Effective concentration required for the activation of human D204E mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human D204E mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	14800 nM Compound: 2-MeSADP	Effective concentration required for the activation of human R287A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human R287A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	15 nM Compound: 2-MeSADP	Effective concentration to activate human Y306A mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration to activate human Y306A mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	15.9 nM Compound: 2-MeSADP	Effective concentration required for the activation of human H132A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human H132A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	15.9 nM Compound: 2-MeSADP	Effective concentration required for the activation of human T221A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human T221A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	16 nM Compound: 2-MeSADP	Effective concentration to activate human Y203F mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration to activate human Y203F mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	17.5 nM Compound: 2-MeSADP	Effective concentration required for the activation of human K198A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human K198A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	17200 nM Compound: 2-MeSADP	Effective concentration required for the activation of human E209A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human E209A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	1790 nM Compound: 2-MeSADP	Effective concentration required for the activation of human K280A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human K280A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	18.2 nM Compound: 2-MeSADP	Effective concentration required for the activation of human F131A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human F131A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	19 nM Compound: 2-MeSADP	Effective concentration to activate human Y306F mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration to activate human Y306F mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	2.2 nM Compound: 2-MeSADP	Effective concentration required for the activation of wild-type P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate is determined in separate experiment Effective concentration required for the activation of wild-type P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate is determined in separate experiment	[PMID: 15481977]
COS-7	EC₅₀	2.5 nM Compound: 2-MeSADP	Effective concentration required for the activation of human K196A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human K196A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	2.6 nM Compound: 2-MeSADP	Effective concentration required for the activation of human R301A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human R301A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	20.7 nM Compound: 2-MeSADP	Effective concentration required for the activation of human F226A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human F226A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	3 nM Compound: 2-MeSADP	Effective concentration to activate wild-type P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration to activate wild-type P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	3.2 nM Compound: 2-MeSADP	Effective concentration required for the activation of human E209D mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human E209D mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	3.6 nM Compound: 2-MeSADP	Effective concentration required for the activation of human D208A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human D208A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	3.9 nM Compound: 2-MeSADP	Effective concentration required for the activation of human D289A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human D289A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	4.7 nM Compound: 2-MeSADP	Effective concentration required for the activation of human R195A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human R195A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	4.9 nM Compound: 2-MeSADP	Effective concentration required for the activation of human E209R mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human E209R mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	418 nM Compound: 2-MeSADP	Effective concentration required for the activation of human R310K mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human R310K mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	455 nM Compound: 2-MeSADP	Effective concentration required for the activation of human Q307A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human Q307A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	5.9 nM Compound: 2-MeSADP	Effective concentration required for the activation of human K125A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human K125A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	5160 nM Compound: 2-MeSADP	Effective concentration required for the activation of human C296A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human C296A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	5290 nM Compound: 2-MeSADP	Effective concentration required for the activation of human R287Q mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human R287Q mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	595 nM Compound: 2-MeSADP	Effective concentration required for the activation of human D204N mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human D204N mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	6 nM Compound: 2-MeSADP	Effective concentration to activate human Y273F mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration to activate human Y273F mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	66.5 nM Compound: 2-MeSADP	Effective concentration required for the activation of human D204A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human D204A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	7.8 nM Compound: 2-MeSADP	Effective concentration required for the activation of human R212A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human R212A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	74.9 nM Compound: 2-MeSADP	Effective concentration required for the activation of human R287K mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human R287K mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	8.6 nM Compound: 2-MeSADP	Effective concentration required for the activation of human E209Q mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human E209Q mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	9.2 nM Compound: 2-MeSADP	Effective concentration required for the activation of human R285A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human R285A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	9.8 nM Compound: 2-MeSADP	Effective concentration required for the activation of human D300A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human D300A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	> 10000 nM Compound: 2-MeSADP	Effective concentration to activate human Y203A (EL2) mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration to activate human Y203A (EL2) mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	> 10000 nM Compound: 2-MeSADP	Effective concentration to activate human Y273A mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration to activate human Y273A mutant strain P2Y1 receptor expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	> 100000 nM Compound: 2-MeSADP	Effective concentration required for the activation of human C124A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human C124A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	> 100000 nM Compound: 2-MeSADP	Effective concentration required for the activation of human C202A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human C202A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	> 100000 nM Compound: 2-MeSADP	Effective concentration required for the activation of human R128A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human R128A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	> 100000 nM Compound: 2-MeSADP	Effective concentration required for the activation of human R287E mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human R287E mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	> 100000 nM Compound: 2-MeSADP	Effective concentration required for the activation of human R310A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human R310A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	EC₅₀	> 100000 nM Compound: 2-MeSADP	Effective concentration required for the activation of human S314A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate Effective concentration required for the activation of human S314A mutant strain P2Y1 receptors expressed in COS-7 cells for the accumulation of inositol phosphate	[PMID: 15481977]
COS-7	IC₅₀	150 nM Compound: 2-MeSADP	Inhibition concentration required against human Y306A mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]MRS2279 as radioligand Inhibition concentration required against human Y306A mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]MRS2279 as radioligand	[PMID: 15481977]
COS-7	IC₅₀	22 nM Compound: 2-MeSADP	Inhibition concentration required against human Y273A mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]-MRS2279 as radioligand Inhibition concentration required against human Y273A mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]-MRS2279 as radioligand	[PMID: 15481977]
COS-7	IC₅₀	24 nM Compound: 2-MeSADP	Inhibition concentration required against wild type strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]-MRS2279 as radioligand Inhibition concentration required against wild type strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]-MRS2279 as radioligand	[PMID: 15481977]
COS-7	IC₅₀	260 nM Compound: 2-MeSADP	Inhibition concentration required against human Y203F mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]MRS2279 as radioligand Inhibition concentration required against human Y203F mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]MRS2279 as radioligand	[PMID: 15481977]
COS-7	IC₅₀	360 nM Compound: 2-MeSADP	Inhibition concentration required against human Y306F mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]MRS2279 as radioligand Inhibition concentration required against human Y306F mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]MRS2279 as radioligand	[PMID: 15481977]
COS-7	IC₅₀	40 nM Compound: 2-MeSADP	Inhibition concentration required against human Y273F mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]MRS2279 as radioligand Inhibition concentration required against human Y273F mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]MRS2279 as radioligand	[PMID: 15481977]
COS-7	IC₅₀	> 10000 nM Compound: 2-MeSADP	Inhibition concentration required against human Y203A (EL2) mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]MRS2279 as radioligand Inhibition concentration required against human Y203A (EL2) mutant strain P2Y1 receptor expressed in COS-7 cells is determined using [3H]MRS2279 as radioligand	[PMID: 15481977]
HEK293	EC₅₀	0.1 μM Compound: 2-MeS-ADP	Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increase Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increase	[PMID: 16539385]

In Vitro

2-MeSADP (Serial dilutions) potently activates human SP174 (P2Y13) in HEK293-EBNA cells cotransfected with Gαq/i3, with an EC₅₀ of 19 nM, making it one of the most potent ligands tested for this receptor^[1].
2-MeSADP (Serial dilutions) potently activates mouse SP174 (P2Y13) in HEK293-EBNA cells cotransfected with Gαq/i3, with an EC₅₀ of 6.2 nM, showing higher potency at the murine receptor than the human ortholog^[1].
2-MeSADP (Serial dilutions; 10 min) potently inhibits forskolin-stimulated cAMP accumulation in HEK293-EBNA cells stably transfected with human SP174 (P2Y₁₃), with an EC₅₀ of 13 nM, confirming coupling of the receptor to Gαi signaling^[1].
2-MeS-ADP (Serial dilutions) potently activates human P2Y12 in HEK293-EBNA cells cotransfected with Gαq/i3, with an EC₅₀ of 5 nM, showing higher potency at P2Y12 than at the related SP174 (P2Y13) receptor^[1].
2-MeSADP (0.2 mg; 3 h) is partially susceptible to hydrolysis by alkaline phosphatase, with 87% degradation observed after a 3-hour incubation at 37 °C^[2].
2-MeSADP (40 mM; up to 24 h) exhibits moderate metabolic stability in human blood serum, with a half-life of 23.5 h at 37 °C^[2].
2-MeSADP (multiple concentrations) potently activates the turkey P2Y1 receptor expressed in human 1321N1 astrocytoma cells, inducing intracellular Ca ²⁺ mobilization with an EC₅₀ of 0.0025 μM^[2].
2-MeSADP (log M values of -7 to -5.5) induces aggregation and shape change in human platelets, and is 3-5 times more potent as an aggregating agent than ADP^[4].
2-MeSADP (log M values of -9 to -7; 2 min) potently inhibits PGE1-stimulated cyclic AMP accumulation in human platelets, with half-maximal inhibition at 6 nM in platelet-rich plasma and 2 nM in washed platelets, and is 150-200 times more potent than ADP for this effect^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

473.29

Formula

C₁₁H₁₇N₅O₁₀P₂S

CAS No.

34983-48-7

SMILES

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(SC)N=C3N)O[C@@H]1COP(OP(O)(O)=O)(O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. HY-108648A-2.pdf [Content Brief]

[2]. HY-108648A-4.pdf [Content Brief]

[3]. Sak K, et al. A retrospective of recombinant P2Y receptor subtypes and their pharmacology. Arch Biochem Biophys. 2002;397(1):131-136. [Content Brief]

[4]. HY-108648A-3.pdf [Content Brief]

2-MeSADP Related Classifications

Neurological Disease

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Keywords:

2-MeSADP34983-48-72-Methylthioadenosine diphosphate 2-Methylthio-ADPP2Y Receptormouse P2Y13human P2Y12human P2Y13HEK293-EBNA cellsP2Y1 receptorintracellular calciumbovine aqueous humorP2Y receptorglaucomahuman plateletsInhibitorinhibitorinhibit

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2-MeSADP (Synonyms: 2-Methylthioadenosine diphosphate; 2-Methylthio-ADP)

Other Forms of 2-MeSADP:

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