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Guanosine 5'-diphosphate ditromethamine

(Synonyms: GDP ditromethamine)
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Guanosine 5'-diphosphate ditromethamine is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate ditromethamine is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate ditromethamine can be used in the research of inflammation, such as anemia of inflammation (AI).

For research use only. We do not sell to patients.

  • CAS No.: 103192-39-8
  • Formula: C18H37N7O17P2
  • Molecular Weight:685.47
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Guanosine 5'-diphosphate ditromethamine Chemical Structure
    Guanosine 5'-diphosphate ditromethamine Chemical Structure
  • Experimental Validation Results for Guanosine 5'-diphosphate ditromethamine
  • Experimental Validation Results for Guanosine 5'-diphosphate ditromethamine
CAS No.: 103192-39-8
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  • Guanosine 5'-diphosphate ditromethamine Chemical Structure
    Guanosine 5'-diphosphate ditromethamine Chemical Structure
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    Guanosine 5'-diphosphate ditromethamine purchased from MedChemExpress. Usage Cited in: Endocrinology. 2023 Aug 1;164(9):bqad114. [Abstract]

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     The mitochondrial respiration of BAT (left) and scWAT (right) was significantly increased at both basal and substrate-induced states in MiR-143 KO mice, and this increase was diminished by guanosine diphosphate (2 mM).

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    Guanosine 5'-diphosphate ditromethamine purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2022 Oct 27;23(21):13058. [Abstract]

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     Guanosine diphosphate (2 mM) inhibited the oxygen consumption of mitochondria isolated from BAT of WT and miR-143 KO mice fed HFD for 1 week.

  • Guanosine 5'-diphosphate ditromethamine