2. Membrane Transporter/Ion Channel Metabolic Enzyme/Protease
  3. Hepcidin Potassium Channel Endogenous Metabolite
  4. Guanosine 5'-diphosphate ditromethamine

Guanosine 5'-diphosphate ditromethamine  (Synonyms: GDP ditromethamine)

Cat. No.: HY-113066B
Handling Instructions Technical Support

Guanosine 5'-diphosphate ditromethamine is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate ditromethamine is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate ditromethamine can be used in the research of inflammation, such as anemia of inflammation (AI).

For research use only. We do not sell to patients.

CAS No. : 103192-39-8

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of Guanosine 5'-diphosphate ditromethamine:

Guanosine 5'-diphosphate ditromethamine Related Antibodies

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Guanosine 5'-diphosphate ditromethamine

Bio/Physico-chemical Assay

    Guanosine 5'-diphosphate ditromethamine purchased from MedChemExpress. Usage Cited in: Endocrinology. 2023 Aug 1;164(9):bqad114.  [Abstract]

    The mitochondrial respiration of BAT (left) and scWAT (right) was significantly increased at both basal and substrate-induced states in MiR-143 KO mice, and this increase was diminished by guanosine diphosphate (2 mM).

    Guanosine 5'-diphosphate ditromethamine purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2022 Oct 27;23(21):13058.  [Abstract]

    Guanosine diphosphate (2 mM) inhibited the oxygen consumption of mitochondria isolated from BAT of WT and miR-143 KO mice fed HFD for 1 week.

    View All Endogenous Metabolite Isoform Specific Products:

    View All Isoforms
    Human Endogenous Metabolite Microbial Metabolite

    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    Guanosine 5'-diphosphate ditromethamine is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate ditromethamine is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate ditromethamine can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].

    IC50 & Target[2]

    Human Endogenous Metabolite

     

    Clinical Trial
    Molecular Weight

    685.47

    Formula

    C18H37N7O17P2
    CAS No.
    SMILES

    O=P(O)(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=C(N)NC3=O)O1)(O)=O)O.OCC(CO)(N)CO.OCC(CO)(N)CO
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
    • No file chosen (Maximum size is: 1024 Kb)
    • If you have published this work, please enter the PubMed ID.
    • Your name will appear on the site.

    Guanosine 5'-diphosphate ditromethamine Related Classifications

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass   Concentration   Volume   Molecular Weight *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Guanosine 5'-diphosphate ditromethamine103192-39-8GDP ditromethamineHepcidinPotassium ChannelEndogenous MetaboliteKcsAK+ channelIL-6/stat-3 pathwayhepcidininflammationanemiaAICaco-2HepG2Inhibitorinhibitorinhibit

    Your Recently Viewed Products:

    Inquiry Online

    Your information is safe with us. * Required Fields.

    Product Name

    		  

    Requested Quantity *

    Applicant Name *

    		 

    Salutation

    Email Address *

    		 

    Phone Number *

    Department

    		 

    Organization Name *

    City

    State

    Country or Region *

    		      

    Remarks

    Bulk Inquiry

    Inquiry Information

    Product Name:
    Guanosine 5'-diphosphate ditromethamine
    Cat. No.:
    HY-113066B
    Quantity:
    MCE Japan Authorized Agent:

    Customer Review

    Thank You for Your Feedback!

    Request for HNMR Report

    Please fill out this form to request the QC report. We will send it to your Email address shortly.

    Your information is safe with us. * Required Fields.

    Product Name

    		  

    Lot #

    Applicant Name *

    		 

    Email Address *

    Phone Number

    		 

    Department *

    Organization Name *

    		 

    Country or Region *

    Remarks

    SAFETY DATA SHEET (SDS)

    Request for HNMR Report

    We have received your request and will respond to you as soon as possible.