2. Membrane Transporter/Ion Channel Metabolic Enzyme/Protease
  3. Hepcidin Potassium Channel Endogenous Metabolite
  4. Guanosine 5'-diphosphate ditromethamine

Guanosine 5'-diphosphate ditromethamine  (Synonyms: GDP ditromethamine)

Cat. No.: HY-113066B
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Guanosine 5'-diphosphate ditromethamine is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate ditromethamine is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate ditromethamine can be used in the research of inflammation, such as anemia of inflammation (AI).

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No. CAS : 103192-39-8

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Other In-stock Forms of Guanosine 5'-diphosphate ditromethamine:

Guanosine 5'-diphosphate ditromethamine Related Antibodies

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Guanosine 5'-diphosphate ditromethamine

Bio/Physico-chemical Assay

    Guanosine 5'-diphosphate ditromethamine purchased from MedChemExpress. Usage Cited in: Endocrinology. 2023 Aug 1;164(9):bqad114.  [Abstract]

    The mitochondrial respiration of BAT (left) and scWAT (right) was significantly increased at both basal and substrate-induced states in MiR-143 KO mice, and this increase was diminished by guanosine diphosphate (2 mM).

    Guanosine 5'-diphosphate ditromethamine purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2022 Oct 27;23(21):13058.  [Abstract]

    Guanosine diphosphate (2 mM) inhibited the oxygen consumption of mitochondria isolated from BAT of WT and miR-143 KO mice fed HFD for 1 week.

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    Descripciòn

    Guanosine 5'-diphosphate ditromethamine is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate ditromethamine is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate ditromethamine can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].

    IC50 & Target[2]

    Human Endogenous Metabolite

     

    Ensayo clínico
    Peso molecular

    685.47

    Fòrmula

    C18H37N7O17P2
    No. CAS
    SMILES

    O=P(O)(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=C(N)NC3=O)O1)(O)=O)O.OCC(CO)(N)CO.OCC(CO)(N)CO
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    Guanosine 5'-diphosphate ditromethamine Related Classifications

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      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Guanosine 5'-diphosphate ditromethamine103192-39-8GDP ditromethamineHepcidinPotassium ChannelEndogenous MetaboliteKcsAK+ channelIL-6/stat-3 pathwayhepcidininflammationanemiaAICaco-2HepG2Inhibitorinhibitorinhibit

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    Nombre del producto:
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