Adenosine 3',5'-diphosphate disodium
Based on 1 Customer Validation
Adenosine 3',5'-diphosphate disodium is an endogenous purine nucleotide. Adenosine 3',5'-diphosphate disodium acts as an inhibitor of bovine adrenal estrogen sulfotransferase (EST) with a Ki value of 7.0 μM. It also serves as an indispensable specific cofactor for the pregnenolone-binding protein (PBP) steroid-binding complex, with an EC50 value of 1.5 μM in guinea pigs.
For research use only. We do not sell to patients.
- Purity: 99.38%
- CAS No.: 75431-54-8
- Formula: C10H13N5Na2O10P2
- Molecular Weight:471.16
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Adenosine 3',5'-diphosphate (10 μM; ice preincubation for 20 min) disodium significantly enhances the pregnenolone-binding capacity of partially purified native guinea pig adrenocortical pregnenolone-binding protein (PBP)[2].
Adenosine 3',5'-diphosphate (ice preincubation for 20 min) disodium restores the pregnenolone-binding capacity of alkaline phosphatase-inactivated guinea pig adrenal cortex pregnenolone-binding protein (PBP) in a saturable and cooperative manner, with a half-maximal effective concentration of 0.15 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 75431-54-8
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Appearance Solid
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Molecular Weight 471.16
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Formula C10H13N5Na2O10P2
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Color White to off-white
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SMILES
O[C@H]([C@@H]1O[P](O)(O[Na])=O)[C@](O[C@@H]1CO[P](O)(O[Na])=O)([H])N2C3=NC=NC(N)=C3N=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 25 mg/mL (53.06 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (281 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.1224 mL | 10.6121 mL | 21.2242 mL | 53.0605 mL |
| 5 mM | 0.4245 mL | 2.1224 mL | 4.2448 mL | 10.6121 mL | |
| 10 mM | 0.2122 mL | 1.0612 mL | 2.1224 mL | 5.3061 mL | |
| 15 mM | 0.1415 mL | 0.7075 mL | 1.4149 mL | 3.5374 mL | |
| 20 mM | 0.1061 mL | 0.5306 mL | 1.0612 mL | 2.6530 mL | |
| 25 mM | 0.0849 mL | 0.4245 mL | 0.8490 mL | 2.1224 mL | |
| 30 mM | 0.0707 mL | 0.3537 mL | 0.7075 mL | 1.7687 mL | |
| 40 mM | 0.0531 mL | 0.2653 mL | 0.5306 mL | 1.3265 mL | |
| 50 mM | 0.0424 mL | 0.2122 mL | 0.4245 mL | 1.0612 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Adenosine 3',5'-diphosphate disodium Related Classifications
HY-137243 Related Classifications
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- Adenosine 3',5'-diphosphate disodium
- 75431-54-8
- Nucleoside Antimetabolite/Analog
- Endogenous Metabolite
- estrone
- guinea pig adrenal cortex
- DNase
- pregnenolone-binding protein
- calf intestinal alkaline phosphatase
- guinea pig
- protease
- 3'-phosphoadenosine 5'-phosphosulfate
- bovine
- bovine adrenal estrogen sulfotransferase
- Inhibitor
- inhibitor
- inhibit