GGPS1 Protein, Human (HEK293, His)
The GGPS1 protein is responsible for catalyzing the trans-addition of three molecules of isopentenyl pyrophosphate (IPP) to dimethylallyl pyrophosphate (DMAPP) to synthesize geranylgeranyl pyrophosphate. This compound is an important precursor for the biosynthesis of carotenoids and geranylated proteins. GGPS1 Protein, Human (HEK293, His) is the recombinant human-derived GGPS1, expressed by HEK293, with C-His labeled tag. The total length of GGPS1 Protein, Human (HEK293, His) is 300 a.a..
- Species: Human
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The GGPS1 protein is responsible for catalyzing the trans-addition of three molecules of isopentenyl pyrophosphate (IPP) to dimethylallyl pyrophosphate (DMAPP) to synthesize geranylgeranyl pyrophosphate. This compound is an important precursor for the biosynthesis of carotenoids and geranylated proteins. GGPS1 Protein, Human (HEK293, His) is the recombinant human-derived GGPS1, expressed by HEK293, with C-His labeled tag. The total length of GGPS1 Protein, Human (HEK293, His) is 300 a.a..
Background
Geranylgeranyl Pyrophosphate Synthase (GGPS1) is an enzyme that catalyzes the trans-addition of three molecules of isopentenyl pyrophosphate (IPP) onto dimethylallyl pyrophosphate (DMAPP), leading to the formation of geranylgeranyl pyrophosphate (GGPP). GGPP serves as a crucial precursor for the biosynthesis of various important molecules, including carotenoids and geranylated proteins. Carotenoids are essential pigments with antioxidant properties, while geranylated proteins are involved in cellular signaling and regulation. The enzymatic activity of GGPS1 is central to the synthesis of GGPP, providing a key building block for the production of biologically significant compounds. Understanding the functions of GGPS1 offers insights into the regulation of pathways related to pigmentation, antioxidant defense, and cellular signaling.
Technical Parameters
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Species Human
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Source HEK293
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Tag C-His
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Accession
O95749 (M1-E300)
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Gene ID9453
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Protein Length
Full Length
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Synonyms
GGPS1; GGPPS1; Geranylgeranyl Diphosphate Synthase 1; Geranylgeranyl Diphosphate Synthase; Geranylgeranyl Pyrophosphate Synthase; GGPP Synthase; (2E,6E)-Farnesyl Diphosphate Synthase; GGPPSase; Dimethylallyltranstransferase; MUDHLOV; Farnesyl Diphosphate
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AA Sequence
MEKTQETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKEENE
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Predicted Molecular Mass
36.3 kDa
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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