Adenosine 2',5'-diphosphate sodium

Name: Adenosine 2',5'-diphosphate sodium
Brand: MedChemExpress
SKU: HY-N7740
Rating: 4.5 (1 reviews)

Cat. No.: HY-N7740: FAQs
Data Sheet SDS COA Handling Instructions

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Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors.

For research use only. We do not sell to patients.

Adenosine 2',5'-diphosphate sodium Chemical Structure

CAS No. : 154146-84-6

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Description

Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors^[1]^[2].

IC₅₀ & Target^[1] ^[1] ^[1] ^[1]

Human Endogenous Metabolite

In Vitro

Adenosine 2',5'-diphosphate non-selectively antagonizes the platelet P2X1 ion channel^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Formula

C₁₀H₁₅N₅O₁₀P₂.xNa

CAS No.

154146-84-6

Appearance

Solid

Color

White to off-white

SMILES

O=[P](O)(O)O[C@H]([C@@H]1O)[C@@](N2C3=NC=NC(N)=C3N=C2)([H])O[C@@H]1CO[P](O)(O)=O.[x].[Na]

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (Need ultrasonic and warming)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

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Data Sheet (274 KB) SDS (251 KB)

COA (258 KB)

Handling Instructions (2659 KB)

References

[1]. Boyer JL, et al. Identification of competitive antagonists of the P2Y1 receptor. Mol Pharmacol. 1996;50(5):1323-1329. [Content Brief]

[2]. Toth-Zsamboki E, et al. The P2Y1 receptor antagonist adenosine-2',5'-diphosphate non-selectively antagonizes the platelet P2X1 ion channel. Thromb Haemost. 2001;86(5):1338-1339. [Content Brief]