Uridine 5'-diphosphate-15N2 dilithium
Uridine 5'-diphosphate-15N2 (UDP-15N2) dilithium is the 15N2-labeled Uridine 5'-diphosphate (HY-113359). Uridine-5'-diphosphate is an important nucleotide made of uracil, ribose, and a pyrophosphate group. Uridine-5'-diphosphate is a potent, selective human P2Y6 receptor native agonist (EC50 = 300 nM; pEC50 = 6.52). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis.
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- Formule: C9H12Li215N2O12P2
- Masse moléculaire:418.01
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 58-98-0
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Masse moléculaire 418.01
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Formule C9H12Li215N2O12P2
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SMILES
O=C(C=C[15N]1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(O[Li])(O[Li])=O)(O)=O)O2)[15NH]C1=O
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Synonyms
UDP-15N2 dilithium
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Ashleigh S Paparella, et al. Clostridioides difficile TcdB Toxin Glucosylates Rho GTPase by an SNi Mechanism and Ion Pair Transition State. ACS Chem Biol. 2022 Sep 16;17(9):2507-2518. [Content Brief]
[3]. Besada P, et al. Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. J Med Chem. 2006 Sep 7;49(18):5532-43. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Uridine 5'-diphosphate-15N2 dilithium Related Classifications
HY-113359AS3 Related Classifications
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