2. Anti-infection
  3. Parasite
  4. Primaquine diphosphate

Primaquine diphosphate  (Synonyms: Primaquine phosphate; Primaquine bisphosphate)

Cat. No.: HY-12651 Purity: 99.61%
COA Handling Instructions

Primaquine Diphosphate (Primaquine phosphate), an 8-aminoquinoline, exerts a broad spectrum of activities against various stages of parasitic malaria. Primaquine Diphosphate remains as the only agent that destroys late hepatic stages and latent tissue forms of Plasmodium vivax and Plasmodium ovale.

For research use only. We do not sell to patients.

Primaquine diphosphate Chemical Structure

Primaquine diphosphate Chemical Structure

CAS No. : 63-45-6

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Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
1 g USD 80 In-stock
Estimated Time of Arrival: December 31
5 g USD 114 In-stock
Estimated Time of Arrival: December 31
10 g USD 192 In-stock
Estimated Time of Arrival: December 31
50 g   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Primaquine diphosphate:

Top Publications Citing Use of Products

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma

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Description

Primaquine Diphosphate (Primaquine phosphate), an 8-aminoquinoline, exerts a broad spectrum of activities against various stages of parasitic malaria. Primaquine Diphosphate remains as the only agent that destroys late hepatic stages and latent tissue forms of Plasmodium vivax and Plasmodium ovale[1][2].

Clinical Trial
Molecular Weight

455.34

Appearance

Solid

Formula

C15H27N3O9P2
CAS No.
SMILES

CC(NC1=C2N=CC=CC2=CC(OC)=C1)CCCN.O=P(O)(O)O.O=P(O)(O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (549.04 mM; Need ultrasonic)

H2O : 25 mg/mL (54.90 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1962 mL 10.9808 mL 21.9616 mL
5 mM 0.4392 mL 2.1962 mL 4.3923 mL
10 mM 0.2196 mL 1.0981 mL 2.1962 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (109.81 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (4.57 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.57 mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.57 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.61%

COA (252 KB) HNMR (229 KB) LCMS (266 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Primaquine diphosphate63-45-6PrimaquinePrimaquine bisphosphateParasiteparasiticmalarialatehepaticstageslatenttissueInhibitorinhibitorinhibit

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